Navigation Links
Finasteride unlikely to induce high grade prostate cancers
Date:9/11/2007

ite.

In a second study, M. Scott Lucia, M.D., of the University of Colorado Health Sciences Center in Denver and colleagues investigated whether finasteride changes the appearance of tumor tissue so that lower-grade tumors are diagnosed as high-grade. The researchers examined surgically-removed prostates and high-grade prostate cancer biopsies from men treated with finasteride and a placebo for signs that finasteride affected prostate size, tumor size, or disease stage.

Like Cohen and colleagues, they found that men treated with finasteride had smaller prostate glands. High-grade tumors were not larger in men taking finasteride, but when they were present in surgically-removed prostates, the tumors were more likely to be detected because the prostates were usually smaller. They also found no major differences in tumor features between the two groups, indicating that it is unlikely that low-grade tumors were being classified as high-grade.

Although the evidence does not exclude the possibility that finasteride may have induced high-grade prostate cancer in some men, the analysis of prostatectomies from the PCPT does indicate that the relative increase in high-grade tumors in the finasteride group is less than originally believed. This evidence further suggests that increased detection may have contributed to the finasteride-associated increase in high-grade disease, the authors write.

In an accompanying editorial, Gerald Andriole, M.D., of Washington University School of Medicine in St. Louis, Mo., and colleagues find the evidence from these two studies important and convincing. Taken together, the studiesprovide substantial reassurance that the increased proportion of high-grade cancer on biopsy in PCPT is not likely to be clinically relevant, the editorialists write. Nevertheless it is necessary, they say, to continue research on the effects of finasteride and other similar drugs such as dutasteride on prostate cancer inciden
'/>"/>

Contact: Liz Savage
jncimedia@oxfordjournals.org
301-841-1287
Journal of the National Cancer Institute
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Finasteride lowers risk of prostate cancer but increases risk of high-grade tumors
2. Finasteride lowers risk of prostate cancer but increases risk of high-grade tumors
3. Fibroids unlikely to Turn Cancerous
4. Men who takes risk is unlikely to impress women
5. An unlikely contender for speedy surgery recovery: Chewing gum
6. New Gastric Cancer Drug Unlikely to Benefit Kidney Cancer Patients
7. Sharon Unlikely To Regain Consciousness
8. People In Pain Are Unlikely To Seek Medical Help
9. Health Targets To Treat Cancer Patients Unlikely To Be Met
10. Avian Flu Unlikely to Spread Through Water Systems
11. Offenders Unlikely to Seek Help
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... PA (PRWEB) January 22, 2015 Woodloch Pines, ... Mountains, has been selected by TripAdvisor as the number one ... the 6th best in the world for their annual Travelers’ ... online travel community . The website is home to millions ...
(Date:1/22/2015)... 2015 Angelweddingdress is a famous wedding dress ... customers to follow it on Facebook, Twitter, and Pinterest. The ... gift. Angelweddingdress draws a lottery every week. , Moreover, the ... 28, 2015. Click Angelweddingdress homepage for more information. ...
(Date:1/22/2015)... TX (PRWEB) January 22, 2015 A ... issue of experience and person-centeredness in the long-term care ... towards action across the continuum. The paper, “The Power ... Continuum,” engages perspectives and practices of the patient, resident ...
(Date:1/22/2015)... 22, 2015 Joan Lunden, award-winning American ... at the upcoming 32nd Annual Miami Breast Cancer ... Education Resource®, LLC (PER®) , shares that “a fast-growing, ... undetected if she had not followed up her clean ...
(Date:1/22/2015)... Boulder, Colorado (PRWEB) January 22, 2015 Four years ... is Queen – which coincided with the marriage of Avasa & ... album, THE ROAD, which is scheduled for release through White Swan ... heartfelt message that there is a sacred path available to all ...
Breaking Medicine News(10 mins):Health News:TripAdvisor Names Woodloch Pines Best Hotel for Families in America 2Health News:TripAdvisor Names Woodloch Pines Best Hotel for Families in America 3Health News:Angelweddingdress Invites Its Customers To Follow It On Facebook, Twitter, And Pinterest 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 2Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 4Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 5Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 6Health News:THE ROAD by Avasa & Matthew Love -- A New Album 2Health News:THE ROAD by Avasa & Matthew Love -- A New Album 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 4
... patients who are infected with Clostridium difficile -- ... will lengthen their stay by about six days on average, ... to controlling the spread of the bacterial infection known as ... 5 in the journal CMAJ , researchers analyzed information ...
... M.D., M.S., assistant professor of medicine at the Indiana ... winner of the mHealth Alliance and Rockefeller Foundation,s Top ... goal is to recognize individuals who have used mobile ... outcomes particularly in the most remote areas of the ...
... , MONDAY, Dec. 5 (HealthDay News) -- Teenagers ... photosensitivity, or light sensitivity, researchers say. The combination ... such as flapping their hands in front of their ... Although photosensitivity occurs in up to 14 percent ...
... -- Children who suffer head trauma can experience headaches months after ... a new study finds. The researchers also found that the ... brain injury (TBI) than after a moderate or severe one. ... , included children aged 5 to 17 who were hospitalized ...
... By Alan Mozes HealthDay Reporter , SUNDAY, ... appear to face an increased risk for seizures while watching ... results did reveal that about one in five of these ... television, including nausea, headaches and dizziness. "Normal people have ...
... obese volunteers participating in a 12-week dietary weight-loss ... higher resting nerve activity compared to weight-loss resistant ... The Endocrine Society,s Journal of Clinical Endocrinology ... system is widely distributed throughout the body and ...
Cached Medicine News:Health News:Common Hospital Infection Lengthens Patient Stays 2Health News:Regenstrief investigator a winner of Top 11 in 2011 Innovator Challenge 2Health News:Girls More Prone Than Boys to Headaches After Head Injury 2Health News:3-D TV Doesn't Raise Seizure Risk for Kids With Epilepsy: Study 2Health News:3-D TV Doesn't Raise Seizure Risk for Kids With Epilepsy: Study 3Health News:Nervous system activity may predict successful weight loss 2
(Date:1/23/2015)... Africa , Jan. 23, 2015   Leatt Corporation ... personal protective equipment for all forms of sports, including ... Leatt-Brace® neck brace, announced today that the UISP Lega ... now requires all riders to wear a neck brace ...
(Date:1/23/2015)... Jan. 23, 2015 Tianyin Pharmaceutical Inc. (NYSE Amex: ... in the development and sale of patented biopharmaceutical medicine, ... pharmaceutical ingredients (API) today announced the business and development ... 1. Following the September 2014 JCM application ...
(Date:1/22/2015)... 2015 /PRNewswire/ - Pivotal Therapeutics Inc. (OTCQX:PVTTF; CSE:PVO), ("Pivotal" or the ... therapies for cardiovascular disease and overall health is pleased to ... 2014 and its outlook for 2015 from the CEO, Mr. ... We would like to take this opportunity to share ...
Breaking Medicine Technology:Leatt Announces Neck Braces Now Required For Motocross/Minicross Racing In Italy 2Leatt Announces Neck Braces Now Required For Motocross/Minicross Racing In Italy 3TPI's JCM Updates on Import Registration for International Clients 2TPI's JCM Updates on Import Registration for International Clients 3TPI's JCM Updates on Import Registration for International Clients 4Pivotal Therapeutics: Year in Review and CEO Update 2Pivotal Therapeutics: Year in Review and CEO Update 3Pivotal Therapeutics: Year in Review and CEO Update 4Pivotal Therapeutics: Year in Review and CEO Update 5Pivotal Therapeutics: Year in Review and CEO Update 6Pivotal Therapeutics: Year in Review and CEO Update 7
... WIRE)--Jun 18, 2007 - Novelos,Therapeutics, Inc. (OTCBB: ... of therapeutics to treat cancer and,hepatitis, today ... Care (DF/PCC) Phase 2 trial of NOV-002,in ... To date, 10 patients were evaluable for ...
... Calif.--(BUSINESS WIRE)--Jun 19, 2007 - Geron,Corporation (Nasdaq: ... production, survival following engraftment and,positive impact on ... for GRNCM1, the company's human embryonic stem ... International,Society for Stem Cell Research (ISSCR) Annual ...
Cached Medicine Technology:Novelos Therapeutics Announces Encouraging Results in Ongoing Phase,2 Ovarian Cancer Trial at Dana-Farber/Partners Cancer Care 2Novelos Therapeutics Announces Encouraging Results in Ongoing Phase,2 Ovarian Cancer Trial at Dana-Farber/Partners Cancer Care 3Research Documents Scalable Production, Survival Following,Engraftment and Positive Impact on Cardiac Function in Infarcted,Rats for Geron's Human Embryonic Stem Cell-Based Therapeutic for,Heart Failure 2Research Documents Scalable Production, Survival Following,Engraftment and Positive Impact on Cardiac Function in Infarcted,Rats for Geron's Human Embryonic Stem Cell-Based Therapeutic for,Heart Failure 3Research Documents Scalable Production, Survival Following,Engraftment and Positive Impact on Cardiac Function in Infarcted,Rats for Geron's Human Embryonic Stem Cell-Based Therapeutic for,Heart Failure 4Research Documents Scalable Production, Survival Following,Engraftment and Positive Impact on Cardiac Function in Infarcted,Rats for Geron's Human Embryonic Stem Cell-Based Therapeutic for,Heart Failure 5Research Documents Scalable Production, Survival Following,Engraftment and Positive Impact on Cardiac Function in Infarcted,Rats for Geron's Human Embryonic Stem Cell-Based Therapeutic for,Heart Failure 6
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: