Navigation Links
Fewer suicides after antidepressive treatment for schizophrenia
Date:5/8/2012

Antidepressive drugs reduce the mortality rate of schizophrenic patients, while treatment with bensodiazepines greatly increases it, especially as regards suicide. Giving several antipsychotics simultaneously, however, seems to have no effect at all. This according to a new study examining different drug combinations administered to patients with schizophrenia.

"We weren't aware that the beneficial effects of antidepressives were so powerful," says Jari Tiihonen, professor of clinical psychiatry at Karolinska Institutet's Department of Clinical Neuroscience in Stockholm, Sweden.

The study followed 2,588 Finns who had recently developed schizophrenia from the time of their initial admission to hospital for an average of four years. By accessing the Finnish registers, the researchers were then able to ascertain the effects of different drug combinations on the mortality risk within the group.

A total of 160 people died in the study, most commonly from external causes such as drowning, poisoning or violent crime, something that affected 57 people. Thirty-five of these cases were suicide, which made it and cardiovascular disease the two main causes of death.

The researchers found that when taking bensodiazepines, the participants ran a 91 per cent higher risk of early death than at times when these drugs were not used. By far the most common cause of death was suicide, and most deaths occurred with patients who had been taking their bensodiazepines for longer than four weeks.

"The increased suicide risk for patients with long-standing benzodiazepine use may be partly attributable to the possible development of withdrawal symptoms when the drugs run out," says Professor Tiihonen. "These symptoms, which can be severe severe anxiety and insomnia, might have affected some of the patients' decisions to commit suicide. It's therefore extremely important that bensodiazepines are discontinued gradually rather than abruptly over a pe
'/>"/>

Contact: Press Officer Katarina Sternudd
katarina.sternudd@ki.se
46-852-483-895
Karolinska Institutet
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Pneumococcal disease: More cases but fewer deaths
2. Physician Groups Call for Fewer Medical Tests
3. Higher-spending hospitals have fewer deaths for emergency patients
4. Fewer U.S. Med Students Choose Psychiatry: Report
5. Ban on Public Smoking Linked to Fewer Preterm Deliveries
6. Fewer women need repeat breast cancer surgeries with new service at University of Michigan
7. In Tougher Economy, Fewer Americans Get Colonoscopy
8. Hispanic Americans Born Outside Country Have Fewer Strokes
9. Recession and high co-pays tied to fewer colonoscopy screenings among people with health insurance
10. Women with rheumatoid arthritis and lupus give birth to fewer children
11. Fewer Teens Exposed to Tobacco Smoke in Cars: Report
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... Steven Reinberg HealthDay Reporter ... who are obese during pregnancy may be more likely to ... suggests. "We found that, compared with children born from ... obese during pregnancy had up to 20 to 30 percent ... an assistant professor of pediatrics at Children,s Hospital of Pittsburgh. ...
(Date:7/22/2014)... hysterectomy using electric power morcellation, uterine cancers were present ... the procedure, according to a study published by ... in which the uterus is fragmented into smaller pieces, ... Despite the commercial availability of electric power morcellators for ... at the time of electric power morcellation (in this ...
(Date:7/22/2014)... heart disease, Dr. Ross Feldman says women are often in ... a men,s-only disease, however, data has shown that post-menopausal women ... and are less likely to be adequately diagnosed and treated. ... the British Journal of Clinical Pharmacology brings to ... helps to identify which women are more prone to heart ...
(Date:7/22/2014)... July 22, 2014 As reported on July ... caller request to name her favorite beauty products, “ Botox ... to say that “ Botox has changed my life” ... makeup chair preparing for her various, daily appearances. “Suddenly ... Ms. Ripa (see: goo.gl/shmTQM). , “I think that Kelly Ripa’s ...
(Date:7/22/2014)... Rochelle, NY -- New guidelines on cholesterol treatment and ... double the risk of dying from atherosclerotic cardiovascular disease ... do women with a similar risk profile (based on ... The implications of this finding for when and how ... Editorial in Journal of Men,s Health , a ...
Breaking Medicine News(10 mins):Health News:Obesity During Pregnancy Linked to Raised Asthma Risk in Kids 2Health News:Obesity During Pregnancy Linked to Raised Asthma Risk in Kids 3Health News:Study examines presence of uterine cancers at the time of hysterectomy using morcellation 2Health News:Gene variant identified as a heart disease risk factor for women 2Health News:Celebrity Botox: Kelly Ripa Confesses to Getting Botox Injections 2
... TUESDAY, May 29 (HealthDay News) -- People with less than ... problems with their thinking skills later in life, according to ... researchers from Harvard University noted that people with more education ... thinking, or so-called "cognitive," skills, even if they had the ...
... HealthDay Reporter , MONDAY, May 28 (HealthDay News) -- Could ... friends sit around? A small study suggests it,s possible: ... they hung out with active kids, and the reverse was ... affect how active kids are, and it,s not clear whether ...
... for suspected HIV is critical, pre-exposure preventive treatment is ... in high-risk groups, states a review of evidence published ... "Although postexposure prophylaxis has a long history of success, ... in the course of infection ("treatment as prevention") are ...
... May 27 (HealthDay News) -- Boosting students, levels of ... says. Swedish researchers followed more than 200 schoolchildren, ... Some children were assigned to an intervention group that ... training in motor-physical skills such as balance and coordination. ...
... from the U.S. Preventive Services Task Force (USPSTF) advising ... cancer in healthy men are likely to encounter serious ... a survey by Johns Hopkins investigators. In ... found that while doctors agreed with older recommendations to ...
... factor receptor cousins mobilize a specialized protein to activate a ... in the May 25 issue of Cell . ... in breast cancer and activation of glucose metabolism (glycolysis), which ... survive. Their research focused on Skp2 E3 ligase, a ...
Cached Medicine News:Health News:Education May Protect Brain From Exposure to Solvents 2Health News:Key to More Active, Slimmer Kids: Friends 2Health News:Antiretroviral treatment for preventing HIV infection: an evidence review for physicians 2Health News:New prostate cancer screening guidelines face a tough sell, study suggests 2Health News:New prostate cancer screening guidelines face a tough sell, study suggests 3Health News:Skp2 activates cancer-promoting, glucose-processing Akt 2Health News:Skp2 activates cancer-promoting, glucose-processing Akt 3
(Date:7/22/2014)... , July 22, 2014 The National ... operate the Center for Space Radiation Research (CSRR) under ... Boerma is an Associate Professor of Pharmaceutical Sciences within ... of Pharmacy Division of Radiation Health. She is located ... will direct a team of investigators working across four ...
(Date:7/22/2014)... Mass. , July 22, 2014  Decision Resources Group ... Canada will remain relatively stagnant at ... despite the fact that percutaneous coronary intervention (PCI) volumes are ... other developed markets, such as the United States ... will be largely driven by the increase in penetration of ...
(Date:7/22/2014)... , July 22, 2014  Decision Resources ... multiple sclerosis (MS) patients currently treated with ... have ever experienced flushing and/or gastrointestinal events ... patients are currently experiencing these side effects, ... effective medical management of such events. In ...
Breaking Medicine Technology:Boerma Led UAMS Team to Establish NSBRI's Center for Space Radiation Research (CSRR) 2Boerma Led UAMS Team to Establish NSBRI's Center for Space Radiation Research (CSRR) 3The Canadian Interventional Cardiology Device Market Will Remain Relatively Stagnant Through 2022 at Around $80 Million 2The Canadian Interventional Cardiology Device Market Will Remain Relatively Stagnant Through 2022 at Around $80 Million 3Over Half of Audited Multiple Sclerosis Patients Currently Treated with Biogen Idec's Tecfidera Have Experienced Minor Side Effects Although Impact on Use Appears Muted 2Over Half of Audited Multiple Sclerosis Patients Currently Treated with Biogen Idec's Tecfidera Have Experienced Minor Side Effects Although Impact on Use Appears Muted 3
... May 26 Isis Pharmaceuticals, Inc. (Nasdaq: ISIS ), the leader in ... its 2010 Annual Meeting of Stockholders and Open House on June 2 from ... , , , ... , , ...
... May 25 Otix Global, Inc. (Nasdaq: OTIX ), ... begun offering franchising opportunities to audiologists and audiometrists throughout Australia ... annual Audiological Society of Australia (ASA) conference in Darling ... American Academy of Audiology conference which is held in the U.S. ...
Cached Medicine Technology:Isis Pharmaceuticals to Present a General Corporate Update at Its 2010 Annual Meeting of Stockholders and Open House 2Isis Pharmaceuticals to Present a General Corporate Update at Its 2010 Annual Meeting of Stockholders and Open House 3Otix Global to Offer Franchise Opportunities in Australia 2Otix Global to Offer Franchise Opportunities in Australia 3
The flexible endoscope was mainly developed for the pure neuroendoscopy. Due to the working channel it is ideal suitable for therapeutic indications e.g. subdural hematomas, cysts or intraventricular...
Bipolar gingivoplasty loop. Individual sterile packs....
... Performance Instrument System. It is the only ... electric power with the unparalleled high performance ... The advanced design of this instrument system ... cooling system, advanced control circuitry, and the ...
... is a high speed pneumatic ... dissection of bone, biometals, bioplastics ... not only provides speed 80,000 ... the control and precision that ...
Medicine Products: