Navigation Links
Few women at high-risk for hereditary breast and ovarian cancer receive genetic counseling
Date:5/8/2014

Mutations in the BRCA1 and BRCA2 genes account for nearly 25 percent of hereditary breast cancers and most hereditary ovarian cancers, yet a study by cancer prevention and control researchers at Virginia Commonwealth University Massey Cancer Center suggests an alarmingly small amount of women who qualify for BRCA genetic counseling actually receive the services. Additionally, they found that a significant proportion of women with a family history of breast and ovarian cancer underestimate their own risk.

The study, published in the April edition of the Journal of Community Genetics, collected data from 486 women over the course of two years. Of these women, 22 met the criteria to be referred for BRCA counseling. However, only one of the women reported receiving genetic counseling and only one reported prior genetic testing. And while perceived risk of developing breast and ovarian cancer was higher among high-risk women, 27 percent of high-risk women felt their risk was "low," and 32 percent felt their risk was "lower than average." Despite having a diverse population, the researchers did not find any significant differences associated with factors such as age, race, family size or the patient's knowledge of genetic testing.

"Despite recommendations from the United States Preventive Services Task Force that primary care physicians screen for hereditary cancer risk, it seems that too few women who meet the eligibility criteria are actually following through with BRCA counseling services," says the study's lead investigator John Quillin, Ph.D., M.P.H., member of the Cancer Prevention and Control research program and genetic counselor in the Familial Cancer Clinic at Virginia Commonwealth University Massey Cancer Center and assistant professor in the Department of Human and Molecular Genetics in the VCU School of Medicine. "Unfortunately, this means that a significant number of women who are at high-risk for developing breast and ovarian cancer may not be taking advantage of preventive measures that could ultimately save their lives."

The researchers analyzed data from a pilot study called Kin Fact (Keeping Information about Family Cancer Tune-up) that was conducted at the VCU Women's Health Clinic. Kin Fact works by having a clinical research associate intervene during a woman's annual gynecology appointment to discuss the patient's genetic cancer risks. Participants were asked to complete a self-administered survey that asked questions about their knowledge of genetic counseling and their perceived cancer risk. After completing the survey, the study's recruiters obtained information about the patient's hereditary cancer risks by noting all breast and ovarian cancers among first-and second-degree relatives. The researchers' goals were to assess the amount of women eligible for BRCA counseling in a primary care setting, explore associations between high-risk status and characteristics such as age, race and genetic literacy, and determine whether high-risk patients received genetic counseling and/or testing.

"We need to examine whether patients are fully aware of their family history, and if there are ways to optimize family history collection in clinical settings," says Quillin. "This will help determine if educational interventions are needed for providers, patients or both."


'/>"/>

Contact: John Wallace
wallacej@vcu.edu
804-628-1550
Virginia Commonwealth University
Source:Eurekalert

Related medicine news :

1. Health screening for low-income women under health care reform: Better or worse?
2. Overestimation of radiation exposure may keep women from critical screening
3. Women with unintended pregnancies take the shortest maternity leaves
4. Women and PAD: Excellent treatment outcomes in spite of disease severity
5. Better sleep predicts longer survival time for women with advanced breast cancer
6. Infertile women want more support
7. Surgeons and health care settings influence type of breast cancer surgery women undergo
8. CWRU researchers profile womens employment, caregiving workloads, effort and health
9. False-positive mammogram anxiety has limited impact on womens well-being
10. May 2 women in science symposium honors Anne Fausto-Sterling
11. Too many diet drinks may spell heart trouble for older women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/17/2017)... (PRWEB) , ... January 17, 2017 , ... ... Medical Center joined the Peoples Health network on Dec. 1, 2016. Peoples ... , “JenCare Senior Medical Center is an exciting addition to our provider network, ...
(Date:1/17/2017)... ... January 17, 2017 , ... Wettstein Agencies, a ... and business professionals throughout central Colorado, is joining local nonprofit Aurora Warms The ... Warms The Night organization is committed to breaking the cycle of homelessness and ...
(Date:1/17/2017)... ... January 17, 2017 , ... The Sharie Withers ... has announced the latest beneficiary of their thriving community involvement program. The current ... to fulfilling the dreams of terminally ill patients. Donations to this worthy cause ...
(Date:1/16/2017)... ... January 17, 2017 , ... To ... internationally recognized leader in the fast-casual category, announces a hearty and wholesome Winter ... Egg Breakfast Sandwich, Turkey Mash-Up Sandwich, Cranberry Crunch & Honey Parfait, Slow Cooked ...
(Date:1/16/2017)... ... January 16, 2017 , ... With the Grand Opening Event planned for ... use by sports teams and the general public. Built in five months by Centerpoint, ... be converted into basketball or pickleball courts. The space is also suitable for indoor ...
Breaking Medicine News(10 mins):
(Date:1/17/2017)... , Jan 17, 2017 Research and ... Market by Type (Innovative, Generic), Manufacturer (Captive, Merchant), Synthesis (Synthetic, Biotech), ... - Global Forecast to 2021" report to their offering. ... The global active ... 2021 from USD 157.95 Billion in 2016, growing at a CAGR ...
(Date:1/17/2017)... 17, 2017 Immune Pharmaceuticals (NASDAQ: ... today that it will hold a Satellite Symposium on February ... (ISAL) XVI in Munich, Germany . ... Efficacy of Immunotherapy for the maintenance of remission in ... 20 th , 2017 from 12:45 – 13:45 CET ...
(Date:1/17/2017)... PARSIPPANY, N.J. , Jan. 17, 2017 Interpace ... that provides clinically useful molecular diagnostic tests and pathology ... it has received a letter dated January 13, 2017 ... it has regained compliance with the requirement of the ... price of $1.00 per share. The letter ...
Breaking Medicine Technology: