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Few DNA repair genes maintain association with cancer in field synopsis
Date:12/30/2008

lish with high confidence the presence of specific associations."

In an accompanying editorial, Ajay Yesupriya, of the National Office of Public Health Genomics at the Centers for Disease Control and Prevention in Atlanta, and colleagues describe an international collaboration of researchers called the Human Genome Epidemiology Network (HuGENet) that advocates a concerted approach to conducting meta-analyses and systematic reviews of literature on gene-disease association studies. The paper by Ioannidis and colleagues is the first HuGENet Field Synopsis on cancer susceptibility.

"The identification of reliable genetic associations is fundamental to the translation of genomic research findings to clinical and public health applications," the editorialists write. "By synthesizing research findings and assessing cumulative evidence, field synopses can recognize the most credible genetic associations."


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Contact: Caroline McNeil
jncimedia@oxfordjournals.org
301-841-1287
Journal of the National Cancer Institute
Source:Eurekalert

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