Navigation Links
Fetal stem cells from placenta may help maternal heart recover from injury
Date:11/14/2011

Researchers from Mount Sinai School of Medicine have discovered the therapeutic benefit of fetal stem cells in helping the maternal heart recover after heart attack or other injury. The research, which marks a significant advancement in cardiac regenerative medicine, was presented today at the American Heart Association's (AHA) Scientific Sessions 2011 in Orlando, Florida, and is also published in the current issue of Circulation Research, a journal of the AHA.

In the first study of its kind, the Mount Sinai researchers found that fetal stem cells from the placenta migrate to the heart of the mother and home to the site where an injury, such as a heart attack, occurred. The stem cells then reprogram themselves as beating heart stem cells to aid in its repair. The scientists also mimicked this reprogramming in vitro, showing that the fetal cells became spontaneously beating heart cells in cell culture, which has broad-reaching implications in treating heart disease.

Previous studies have documented a phenomenon in which half of women with a type of heart failure called peripartum cardiomyopathy saw their condition spontaneously recover in the months following pregnancy. Based on this evidence, the Mount Sinai team wanted to determine whether fetal stem cells played a role in maternal recovery.

They evaluated the hearts of pregnant female mice that underwent mid-gestation heart injury and survived. Using green fluorescent protein in the fetuses to tag the fetal stem cells derived from the placenta, they found that the green fluorescent stem cells homed to the injured hearts of their mothers, grafted onto the damaged tissue, and differentiated into smooth muscle cells, blood vessel cells, or another type of heart cell called cardiomyocytes.

"Our research shows that fetal stem cells play an important role in inducing maternal cardiac repair," said Hina Chaudhry, MD, Director of Cardiovascular Regenerative Medicine at Mount Sina
'/>"/>

Contact: Mount Sinai Press Office
newsmedia@mssm.edu
212-241-9200
The Mount Sinai Hospital / Mount Sinai School of Medicine
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Links to Mental Illness Seen in Fetal Brains: Study
2. Fetal Exposure to Magnetic Fields From Appliances, Power Lines May Up Kids Asthma Risk
3. NICHD renews maternal-fetal medicine, neonatal ties with Women & Infants
4. Fetal Exposure to Common Epilepsy Drugs May Harm Kids IQ: FDA
5. Fetal electrocardiogram helps in early detection of neonatal acidosis
6. Fetal programming of disease risk to next generation depends on parental gender
7. The TET1 enzyme steers us through fetal development and fights cancer
8. Society for Maternal-Fetal Medicine commends FDA on makena announcement
9. Study finds that electronic fetal heart rate monitoring greatly reduces infant mortality
10. Study finds even with fetal lung maturity, babies delivered prior to 39 weeks are at risk
11. Fetal Surgery Could Boost Outcomes in Severe Spina Bifida
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... The Marietta cosmetic dentists at Verde Pointe Dental ... school and college students heading back to school during the ... safe, professional strength system, as the Marietta dentists believe a ... important stages in life. , Many students have gone through ... whitened. "After braces, teeth can be straight without the ...
(Date:7/28/2014)... Treat skin to a true cleansing with the ... and tomorrow only (while supplies last), take 40% off at ... for two specific users: , 1) those with oily skin ... and , 2) aging skin to help reduce lines, exfoliate ... of Sublime Beauty®. , Those with oily skin can use ...
(Date:7/28/2014)... Alexandria, VA (PRWEB) July 29, 2014 ... of the Social Security disability trust fund by reallocating ... to a new poll by The Senior Citizens ... seniors polled said shifting revenues from the Social Security ... best way to fix the disability program’s financing. “TSCL ...
(Date:7/28/2014)... We have long known that they monopolize large amounts ... tumor cells are also characterized by a series of ... an ordered set. Researchers are calling this behavior "mesenchymal," ... Etienne Meylan,s research team was able to demonstrate that ... behavior result from the same mechanism, at least ...
(Date:7/28/2014)... Mirada, CA (PRWEB) July 28, 2014 ... seeking to pilot an airplane, helicopter, gyroplan or airship, ... Those hoping to pilot balloons and gliders are exempt ... of the physical exam is to alert potential pilots ... prevent safe aviation. By detecting these conditions early, the ...
Breaking Medicine News(10 mins):Health News:Back to School Teeth Whitening Extravaganza For High School Students and Collegiates During August 2014 2Health News:Back to School Teeth Whitening Extravaganza For High School Students and Collegiates During August 2014 3Health News:Clear, Clean Skin With the New Salicylic Wash from Sublime Beauty®; Enlivens Skin, Unclogs Pores 2Health News:The Senior Citizens League Finds No Support Among Seniors for Likely Disability Trust Fund Fix 2Health News:The Senior Citizens League Finds No Support Among Seniors for Likely Disability Trust Fund Fix 3Health News:Cancer: Tumors absorb sugar for mobility 2Health News:Healthpointe Invites All Aspiring Pilots to Complete an FAA Certified Exam 2
... ... manages new facility , ... IL (Vocus) May 24, 2010 -- AthletiCo Physical and Occupational Therapy announces the ... The new facility is located in the Hillcrest Center across the street from the ...
... ... Designers , ... WI (PRWEB) May 24, 2010 -- InPro Corporation announced it has joined the American ... American Academy of Healthcare Interior Designers certifies the knowledge, skills and abilities of healthcare ...
... ... IRB held a ribbon cutting ceremony to celebrate its expansion into new office space in ... office space downtown Seattle, maintains an office in Vancouver, B.C., supports a number of employees ... and the U.S.. , ...
... ... needs many things. It,s 501(c)(3) application is filed, it has a bank account, ... site is in development. What it needs now is a logo, and it ... people and organizations including The Spice House, singer Gretchen Wilson, and writer Michael Z. ...
... and men to undergo bone marrow transplantation to treat ... a new analysis published early online in Cancer ... The study,s results indicate that additional research is needed ... marrow transplantation and also that the medical community should ...
... build strength and flexibility, aids relaxation, experts say , ... for pregnant women, as long as they approach the ... "Women who are expecting can benefit greatly from exercise, ... of their limitations," orthopaedic surgeon and mom-to-be Dr. Rachel ...
Cached Medicine News:Health News:AthletiCo's Champaign-Urbana Physical Therapy Center Relocates to 2040 S. Neil in Champaign 2Health News:AthletiCo's Champaign-Urbana Physical Therapy Center Relocates to 2040 S. Neil in Champaign 3Health News:InPro Becomes AAHID Industry Partner 2Health News:Quorum Review IRB Commemorates New Office with Ribbon Cutting Ceremony 2Health News:Art Contest for New Charity With A History 2Health News:Art Contest for New Charity With A History 3Health News:Art Contest for New Charity With A History 4Health News:African-Americans and women are less likely to undergo bone marrow transplantation 2Health News:Yoga's Benefits Outweigh Risks for Pregnant Women 2
(Date:7/28/2014)... 2014  UBM Medica US announces that ... medical imaging professionals, explored the complex situation regarding ... The shift from fee-for-service has left radiology ... reimbursement is determined in the new payment model . ... the field, who recognized the complexity of the radiologist,s ...
(Date:7/28/2014)... , July 28, 2014 Research and Markets ... Drugs Market 2014-2018" report to their offering. ... chronic disease that leads to inflammation and pain in the ... ankles. In addition, it causes inflammation of the tissues that ... The symptoms of RA begin slowly, usually just mild ...
(Date:7/28/2014)...  Houston dentist , Dr. Behzad ... with Invisalign. With access to this increasingly popular ... straightened without feeling self-conscious in the process. Invisalign ... types of braces, but patients who choose Invisalign ... better support for their oral health and comfort ...
Breaking Medicine Technology:Diagnostic Imaging Delves into Measuring the Radiologist's Value 2Global Rheumatoid Arthritis Drugs Market 2014-2018 2Houston Cosmetic Dentist, Dr. Behzad Nazari, Now Offers Orthodontic Treatment with Invisalign 2
... Iceland, December 14 In one of the,largest studies ... from,deCODE genetics (Nasdaq: DCGN ) today report the ... human genome found to influence obesity. The study,analyzed more ... than 30,000 people from Iceland, the Netherlands, and the ...
... data from two early,clinical studies show that RAD001(R) (everolimus) ... metastatic breast,cancer. These results support the initiation of a ... of RAD001 (proposed brand name,Afinitor(R)) in breast cancer. , ... studies were presented today during the CTRC-AACR San Antonio,Breast ...
Cached Medicine Technology:Major deCODE-led Study Underscores Role of the Brain in Obesity 2Major deCODE-led Study Underscores Role of the Brain in Obesity 3Major deCODE-led Study Underscores Role of the Brain in Obesity 4Major deCODE-led Study Underscores Role of the Brain in Obesity 5RAD001 Shows Potential to Reverse Resistance to Herceptin(R)* in Metastatic Breast Cancer Patients, Leading to Phase III Trial 2RAD001 Shows Potential to Reverse Resistance to Herceptin(R)* in Metastatic Breast Cancer Patients, Leading to Phase III Trial 3RAD001 Shows Potential to Reverse Resistance to Herceptin(R)* in Metastatic Breast Cancer Patients, Leading to Phase III Trial 4RAD001 Shows Potential to Reverse Resistance to Herceptin(R)* in Metastatic Breast Cancer Patients, Leading to Phase III Trial 5RAD001 Shows Potential to Reverse Resistance to Herceptin(R)* in Metastatic Breast Cancer Patients, Leading to Phase III Trial 6RAD001 Shows Potential to Reverse Resistance to Herceptin(R)* in Metastatic Breast Cancer Patients, Leading to Phase III Trial 7
Ballard trach care HMES and filters, tv 1500, HME with built-in flex tube...
... helps provide protection to the exposed airway of ... lightweight making it ideal for active young children ... of heat and moisture recovery, it ensures patient ... and filters have ISO standard tapered ends to ...
... protection to the exposed airway of the tracheostomy ... it ideal for active young children as well ... and moisture recovery, it ensures patient comfort and ... have ISO standard tapered ends to assure a ...
For use with: , pulmonary function testing , nebulizer compressors , humidifiers , concentrators , proximal pressure lines ...
Medicine Products: