Navigation Links
Fetal alcohol exposure affects brain structure in children
Date:11/24/2012

CHICAGO Children exposed to alcohol during fetal development exhibit changes in brain structure and metabolism that are visible using various imaging techniques, according to a new study being presented today at the annual meeting of the Radiological Society of North America (RSNA).

Alcohol use by expectant mothers can lead to problems with the mental and physical development of their childrena condition known as fetal alcohol syndrome. Research suggests an incidence of 0.2 to 1.5 per 1,000 live births, according to the Centers for Disease Control and Prevention. Costs for care of individuals affected by fetal alcohol syndrome in the U.S. have been estimated at $4 billion annually.

Advancements in magnetic resonance imaging (MRI) are affording unprecedented insights into the effects of alcohol on the central nervous systems of children whose mothers drank alcohol during their pregnancy. Recently, researchers in Poland used three different MRI techniques to better define these effects.

The study group included 200 children who were exposed to alcohol during their fetal stage and 30 children whose mothers did not drink while pregnant or during lactation. Researchers used MRI to evaluate the size and shape of the corpus callosum, the bundle of nerve fibers that forms the major communication link between the right and left halves of the brain, in the two groups. Prenatal alcohol exposure is the major cause of impaired development or complete absence of the corpus callosum.

The MRI results showed statistically significant thinning of the corpus callosum in the children exposed to alcohol compared with the other group.

"These changes are strongly associated with psychological problems in children," said Andrzej Urbanik, M.D., chair of the Department of Radiology at Jagiellonian University in Krakow, Poland.

Dr. Urbanik and colleagues also used diffusion weighted imaging (DWI) to study six areas of the central nervous system in the children. DWI maps the diffusion process of water and can be a more sensitive means than traditional MRI for detecting tissue abnormalities.

Children in the alcohol group exhibited statistically significant increases in diffusion on DWI compared with the other children.

"The increase of diffusion indicates neurological disorders or damage to the brain tissue," Dr. Urbanik said.

To noninvasively study metabolism in the brains of the children, the researchers used proton (hydrogen) magnetic resonance spectroscopy (HMRS), a common adjunct to structural MRI studies. HMRS results showed a complex collection of metabolic changes.

"In individual cases, we found a high degree of metabolic changes that were specific for particular locations within the brain," Dr. Urbanik said.


'/>"/>

Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America
Source:Eurekalert

Related medicine news :

1. Dangerous experiment in fetal engineering
2. Pregnant Mothers Gut Changes May Support Fetal Growth
3. New Stanford method enables sequencing of fetal genomes using only maternal blood sample
4. 3 types of fetal cells can migrate into maternal organs during pregnancy
5. Presence of fetal cells in women lowers risk of breast cancer but raises risk of colon cancer
6. Frequency of alcohol consumption and cardiovascular risk factors
7. Alcohol provides protective effect, reduces mortality substantial
8. Alcoholic Drinks Add 100 Calories a Day to Average Adults Diet: Study
9. Effects of alcohol on lymphoma, leukemia, and other types of hematological cancers
10. Genetic link between pancreatitis and alcohol consumption, says Pitt team
11. Alcoholism Linked to Poor Sense of Empathy, Irony in Men
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2017)... BOSTON, MA (PRWEB) , ... June 27, 2017 , ... ... U.S. Senate bill to repeal and replace the 2010 Patient Protection and Affordable Care ... as compared with what would be expected under current law. , More than 20 ...
(Date:6/27/2017)... , ... June 27, 2017 , ... ... assistance and personal financial planning services to residents of southern New Hampshire, is ... event that promises to fight hunger and homelessness in the region. , New ...
(Date:6/27/2017)... ... ... Hammer Strength, the world’s leading performance strength training brand, and the National Basketball ... NBSCA Strength & Conditioning Coach of the Year. , In its 11th year, ... the coach who embodies the highest level of excellence and outstanding service to their ...
(Date:6/26/2017)... (PRWEB) , ... June 26, 2017 , ... Torrance dentist, ... aesthetics can be one of the most noticeable aspects of a person’s appearance. A ... not everyone is born with beautiful, balanced teeth, everyone can have the smile of ...
(Date:6/26/2017)... ... June 26, 2017 , ... A new and improved Orgasm-Shot ... look and feel about themselves and their sexual encounters. A unique medical practice ... leakage head on with a ground breaking medical technique aimed to give women ...
Breaking Medicine News(10 mins):
(Date:5/29/2017)... Israel, May 29, 2017  Cellect Biotechnology Ltd. (NASDAQ: ... technology which enables the functional selection of stem cells, ... for the first quarter ended March 31 st , ... our accomplishments in the first quarter of 2017," said ... quarter, we announced the treatment of the first blood ...
(Date:5/24/2017)...  ivWatch LLC today announced the launch of ... enable seamless integration of ivWatch,s groundbreaking IV infiltration ... and other devices. By integrating ivWatch technology into ... health care customers deliver a higher level of ... therapy. "The ivWatch OEM Board provides ...
(Date:5/22/2017)... , May 22, 2017  As the specialty ... whole continue to make the revolutionary shift from ... important for ensuring positive patient outcomes and shaping ... are shifting focus away from clinical trials and ... of long-term specialty drug therapy utilization in precise ...
Breaking Medicine Technology: