Navigation Links
Fetal Exposure to Arsenic Affects Genes
Date:11/23/2007

Contaminated water could boost child's cancer risk, study finds

FRIDAY, Nov. 23 (HealthDay News) -- Children of women exposed to arsenic-contaminated water during pregnancy have gene expression changes that may result in cancer and other diseases later in life, a Massachusetts Institute of Technology study suggests.

The researchers, who said their work is the first documentation of widespread genetic changes caused by prenatal exposure to an environmental contaminant, analyzed umbilical cord blood from the children of 32 mothers in an area of Thailand with heavy mining-related arsenic contamination. Similar levels of arsenic are found in many other parts of the world, including the U.S. Southwest.

Children who were exposed to arsenic in the womb had about 450 genes that were either significantly more active (in most cases) or less active than the same genes in unexposed children.

Most of the gene expression changes detected in the exposed children are associated with inflammation, which can lead to increased cancer risk. It's not clear how long these gene expression changes may last, and the researchers plan to continue testing the children.

The researchers also found that a subset of 11 of these genes could be used as a highly reliable test for determining whether a child had been exposed to arsenic while in the womb.

The study was published in the Nov. 23 issue of the journal PLoS Genetics.

More information

The U.S. Agency for Toxic Substance and Disease Registry has more about arsenic.



-- Robert Preidt



SOURCE: Massachusetts Institute of Technology, news release, Nov. 23, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Mothers Blood Could Offer Insights Into Fetal Health
2. Residual fetal cells in women may provide protection against breast cancer
3. Fetal cell transplant could be a hidden link between childbirth and reduced risk of breast cancer
4. Fetal Surgery Saves Baby After Early Water Break
5. Fetal heart rate yields clues to childrens later development
6. Fetal Heart Rate Points to Later Child Development
7. Acting Surgeon General Announces National Initiatives to Protect Children by Reducing Exposure to Secondhand Smoke
8. Penn School of Medicine receives $2.3 million to study biomarkers of cigarette smoke exposure
9. Teamsters Applaud Passage of Legislation to Protect Workers From Diacetyl Exposure
10. R rating might be unlikely to affect teens exposure to smoking in movies
11. Occupational exposures may be linked to death from autoimmune disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/26/2017)... (PRWEB) , ... May 26, 2017 , ... ... gather at Boston CEO 2017 on May 30th and 31st at The Four ... forum for leading executives in the life sciences, offering exclusive access to key ...
(Date:5/26/2017)... ... 26, 2017 , ... Amir Qureshi, MD is the first physician in Arkansas ... stimulation system. The Nuvectra™ Algovita SCS System has been FDA approved as a treatment ... in Arkansas to introduce the most powerful SCS system and the only stretchable lead ...
(Date:5/26/2017)... ... , ... A new analysis of community health data reveals that four out ... Midwest. With the average cost of healthcare rising and the U.S. senior population expected ... and affordability of where they live. An annual 2017 report looked at a variety ...
(Date:5/26/2017)... ... May 26, 2017 , ... ... ever copper, antimicrobial, mesh back 24/7 task chair specifically designed for clinical areas. ... “We are thrilled to partner with Cupron® to provide customers with a game ...
(Date:5/26/2017)... (PRWEB) , ... May 26, 2017 , ... After raising ... Antzy Top gadget will continue to be available at a discounted crowdfunding price on ... with stress wherever they are, I also wanted to bring a fidget toy to ...
Breaking Medicine News(10 mins):
(Date:5/9/2017)... Zimmer Biomet Holdings, Inc. (NYSE and SIX: ... it has earned a spot on Forbes, ... was ranked among 500 U.S. employers as well as ... and Services. The annual Forbes ... survey of over 30,000 employees across 25 industries. The ...
(Date:5/9/2017)... 9, 2017  Semler Scientific, Inc. (OTCQB: SMLR), ... to improve the clinical effectiveness and efficiency of ... first quarter ended March 31, 2017. ... customers to identify when preventive care options are ... like heart attacks or strokes occur," said ...
(Date:5/6/2017)... Texas , May 5, 2017   Provista , ... with more than 200,000 customers, today announced Jim Cunniff ... a wealth of executive and business experience to Provista, including ... compounding pharmacy in California . He assumed ... "Jim is a great fit for Provista," says ...
Breaking Medicine Technology: