Navigation Links
Fetal Exposure to Arsenic Affects Genes

Contaminated water could boost child's cancer risk, study finds

FRIDAY, Nov. 23 (HealthDay News) -- Children of women exposed to arsenic-contaminated water during pregnancy have gene expression changes that may result in cancer and other diseases later in life, a Massachusetts Institute of Technology study suggests.

The researchers, who said their work is the first documentation of widespread genetic changes caused by prenatal exposure to an environmental contaminant, analyzed umbilical cord blood from the children of 32 mothers in an area of Thailand with heavy mining-related arsenic contamination. Similar levels of arsenic are found in many other parts of the world, including the U.S. Southwest.

Children who were exposed to arsenic in the womb had about 450 genes that were either significantly more active (in most cases) or less active than the same genes in unexposed children.

Most of the gene expression changes detected in the exposed children are associated with inflammation, which can lead to increased cancer risk. It's not clear how long these gene expression changes may last, and the researchers plan to continue testing the children.

The researchers also found that a subset of 11 of these genes could be used as a highly reliable test for determining whether a child had been exposed to arsenic while in the womb.

The study was published in the Nov. 23 issue of the journal PLoS Genetics.

More information

The U.S. Agency for Toxic Substance and Disease Registry has more about arsenic.

-- Robert Preidt

SOURCE: Massachusetts Institute of Technology, news release, Nov. 23, 2007

Copyright©2007 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Mothers Blood Could Offer Insights Into Fetal Health
2. Residual fetal cells in women may provide protection against breast cancer
3. Fetal cell transplant could be a hidden link between childbirth and reduced risk of breast cancer
4. Fetal Surgery Saves Baby After Early Water Break
5. Fetal heart rate yields clues to childrens later development
6. Fetal Heart Rate Points to Later Child Development
7. Acting Surgeon General Announces National Initiatives to Protect Children by Reducing Exposure to Secondhand Smoke
8. Penn School of Medicine receives $2.3 million to study biomarkers of cigarette smoke exposure
9. Teamsters Applaud Passage of Legislation to Protect Workers From Diacetyl Exposure
10. R rating might be unlikely to affect teens exposure to smoking in movies
11. Occupational exposures may be linked to death from autoimmune disease
Post Your Comments:
(Date:11/27/2015)... , ... November 27, 2015 , ... ... the health care in America. As people age, more care is needed, especially ... are rising, and medical professionals are being overworked. The forgotten part of this ...
(Date:11/27/2015)... (PRWEB) , ... November 27, 2015 , ... ... the November 27th edition of USA Today in Atlanta, Dallas, New York, Minneapolis, ... of 750,000. The digital component is distributed nationally, through a vast social media ...
(Date:11/27/2015)... ... 27, 2015 , ... A simply groundbreaking television series, "Voices in America", which ... into an array of issues that are presently affecting Americans. Dedicated to providing the ... show is changing the subjects consumers focus on, one episode at a time. ...
(Date:11/27/2015)... CA (PRWEB) , ... November 27, 2015 , ... ... California Medical Associates, Inc. and Dr. Tucker Bierbaum with Emergency Medicine at ... They observed that both STEMI and Sepsis conditions present in similar ways and require ...
(Date:11/26/2015)... ON (PRWEB) , ... November 26, 2015 , ... ... of a real-time eReferral system for diagnostic imaging in the Waterloo region. Using ... BMD and Nuclear Medicine tests directly from their electronic medical record (EMR) without ...
Breaking Medicine News(10 mins):
(Date:11/27/2015)... 26, 2015 ... the "2016 Global Tumor Marker Testing ... and Sales Segment Forecasts, Innovative Technologies, Instrumentation ... to their offering. --> ... "2016 Global Tumor Marker Testing Market: ...
(Date:11/26/2015)... November 26, 2015 Un nuevo ... Bremachlorin para el cáncer avanzado.   --> ... terapia fotodinámica de Bremachlorin para el cáncer avanzado. ... la inmunoterapia con la terapia fotodinámica de Bremachlorin para ... Research . --> Clinical Cancer Research . ...
(Date:11/26/2015)... 26, 2015 --> ... approach blends immunotherapy with Bremachlorin-photodynamic therapy for advanced cancer. ... blends immunotherapy with Bremachlorin-photodynamic therapy for advanced cancer. ... blends immunotherapy with Bremachlorin-photodynamic therapy for advanced cancer. ... found that immunotherapy can be efficiently combined with photodynamic ...
Breaking Medicine Technology: