Navigation Links
Fetal Exposure to Arsenic Affects Genes
Date:11/23/2007

Contaminated water could boost child's cancer risk, study finds

FRIDAY, Nov. 23 (HealthDay News) -- Children of women exposed to arsenic-contaminated water during pregnancy have gene expression changes that may result in cancer and other diseases later in life, a Massachusetts Institute of Technology study suggests.

The researchers, who said their work is the first documentation of widespread genetic changes caused by prenatal exposure to an environmental contaminant, analyzed umbilical cord blood from the children of 32 mothers in an area of Thailand with heavy mining-related arsenic contamination. Similar levels of arsenic are found in many other parts of the world, including the U.S. Southwest.

Children who were exposed to arsenic in the womb had about 450 genes that were either significantly more active (in most cases) or less active than the same genes in unexposed children.

Most of the gene expression changes detected in the exposed children are associated with inflammation, which can lead to increased cancer risk. It's not clear how long these gene expression changes may last, and the researchers plan to continue testing the children.

The researchers also found that a subset of 11 of these genes could be used as a highly reliable test for determining whether a child had been exposed to arsenic while in the womb.

The study was published in the Nov. 23 issue of the journal PLoS Genetics.

More information

The U.S. Agency for Toxic Substance and Disease Registry has more about arsenic.



-- Robert Preidt



SOURCE: Massachusetts Institute of Technology, news release, Nov. 23, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Mothers Blood Could Offer Insights Into Fetal Health
2. Residual fetal cells in women may provide protection against breast cancer
3. Fetal cell transplant could be a hidden link between childbirth and reduced risk of breast cancer
4. Fetal Surgery Saves Baby After Early Water Break
5. Fetal heart rate yields clues to childrens later development
6. Fetal Heart Rate Points to Later Child Development
7. Acting Surgeon General Announces National Initiatives to Protect Children by Reducing Exposure to Secondhand Smoke
8. Penn School of Medicine receives $2.3 million to study biomarkers of cigarette smoke exposure
9. Teamsters Applaud Passage of Legislation to Protect Workers From Diacetyl Exposure
10. R rating might be unlikely to affect teens exposure to smoking in movies
11. Occupational exposures may be linked to death from autoimmune disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/10/2016)... ... February 09, 2016 , ... ... the cause of injury may be one of many possible sources: sports, car ... Continuing Education Course , Mastering Rehab Solutions for the Complexities of Concussions ...
(Date:2/9/2016)... ... February 09, 2016 , ... ... businesses recover after a disaster, announced today the acquisition of Hawaii DKI. Hawaii ... , “Investing in like-minded companies who excel at service and response ...
(Date:2/9/2016)... ... February 09, 2016 , ... Cirracore Enterprise ... enterprises move workloads to the cloud. Cirracore provides a secure VMware® vCloud ... traversing the Internet. Transformation Solutions (TSL Partners) provides a full range of ...
(Date:2/9/2016)... ... February 09, 2016 , ... On January 12, 2016 Paul McElwee, a CroppMetcalfe ... noticed their furnace not producing any heat. Shortly after entering the home, Paul was ... was leaking dangerous levels of carbon monoxide into the home, at 2,000 parts per ...
(Date:2/9/2016)... ... February 09, 2016 , ... ZipHearing.com is proud ... affordable hearing aids , increase industry transparency, and promote awareness of hearing ... , “For the average consumer, the hearing aid industry is esoteric and difficult ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... India , February 10, 2016 ... The "Personalized Medicine, Targeted Therapeutics and Companion Diagnostic ... Trends, Technologies, Participants, and Environment" research report indicates ... worth over $149 billion by 2020 growing at ... up of companion diagnostics and targeted therapeutics and ...
(Date:2/9/2016)... Feb. 9, 2016  Landauer, Inc. (NYSE: LDR ... measurement and monitoring, outsourced medical physics services and high ... its fiscal 2016 first quarter ended December 31, 2015. ... Fiscal 2016 First Quarter Highlights , Revenue of ... quarter of 2015 , Domestic Radiation Measurement services revenues ...
(Date:2/9/2016)... , Feb. 9, 2016  Jazz Pharmaceuticals plc ... report its 2015 fourth quarter and full year financial ... of the financial markets.  Company management will host a ... p.m. EST/9:30 p.m. GMT to discuss fourth quarter and ... and financial update and guidance for 2016 financial results. ...
Breaking Medicine Technology: