Navigation Links
Fertility therapy not associated with long-term cardiovascular disease
Date:7/31/2013

Women who gave birth following fertility treatment had no long-term increased risk of death or major cardiovascular events compared to women who gave birth without fertility therapy, according to new research by the Institute for Clinical Evaluative Sciences (ICES) and Women's College Hospital.

The findings, published today in the Journal of the American College of Cardiology, are the first to show fertility medications, which can cause short-term pregnancy complications, are not associated with an increased risk of cardiovascular disease later in life.

"The speculated association between fertility therapy and subsequent cardiovascular disease is not surprising given that more women are waiting until an older age to have children, when they are at greater risk of developing heart disease," said Dr. Jacob Udell, lead author of the study and cardiologist at Women's College Hospital.

Fertility therapy is used in nearly one percent of all successful pregnancies in North America. But these medications are known to cause short-term complications such as gestational diabetes and hypertension. These short-term risks, however, do not translate into lasting cardiovascular damage according to the researchers.

In the study, researchers assessed the long-term risk of stroke, heart attack and heart failure following fertility therapy among 1.1 million women after delivery over a 17-year follow-up period in Ontario. They found:

  • A five-fold increase in the use of fertility therapy from 1993 to 2010, particularly among older women.
  • The use of fertility therapy was associated with an increase in pregnancy complications including a near 30 per cent increase of diabetes in pregnancy, 16 per cent increase in placental disorders and a 10 per cent increase in pre-eclampsia.
  • Women who delivered following fertility therapy had about half the risk of subsequent death compared to women who did not have fertility therapy.
  • Women who delivered following fertility therapy had nearly half the risk of major cardiovascular events such as stroke, heart attack and heart failure. The researchers do not believe that this is a direct effect of treatment; rather that women undergoing fertility therapy maintain a healthy lifestyle over a long period.
  • Researchers reported no increase in the risk of future breast or ovarian cancer in women who gave birth following fertility therapy.
  • Women who had fertility therapy also experienced fewer mental health events, including one-third the rate of depression and one-sixth the rate of self-harm.

"Our findings provide some reassurance that fertility therapy does not appear to increase long-term risk of cardiovascular events following successful pregnancy," says Dr. Donald Redelmeier, co-author of the study and a senior scientist at ICES. "The existing literature provides mixed messages, with our results yielding a relatively favourable assessment."

One theory is that women who seek fertility therapy maintain healthier behavior after a successful delivery a pattern that extends across age and income groups, the researchers say. "Those with successful outcomes may have a powerful and durable change to their lifestyle," says Dr. Redelmeier. "Unknown protective mechanism may also contribute."

"Our findings are encouraging but further research is necessary to explain the full impact of fertility therapy on women's health," Dr. Udell adds. "With a better understanding of the long-term health effects associated with fertility therapy, we can help inform decision making and reduce potential health risks to women."


'/>"/>

Contact: Julie Saccone
julie.saccone@wchospital.ca
416-323-6400 x4054
Women's College Hospital
Source:Eurekalert

Related medicine news :

1. Women working shifts are at greater risk of miscarriage, menstrual disruption and subfertility
2. Fertility Specialist Calls Atlantic Article Disputing Age-Related Fertility Decline “Irresponsible”
3. Fairhaven Health's Dr. Amos Grunebaum Says Fertility Awareness Leads to Babies
4. Fertility Solutions Welcomes a New Doctor, Dr. Vasiliki Moragianni
5. Fertility Clinics in Australia Industry Market Research Report Now Available from IBISWorld
6. Public Funding Spurs Couples to Seek Fertility Treatment
7. Testosterone Supplements May Hurt Male Fertility, Study Finds
8. Can High-Protein, Low-Carb Diet Boost Fertility Treatment?
9. Economics influence fertility rates more than other factors
10. Orange County Fertility Specialist Dr. Jane L. Frederick Donates $50,000 for Surrogate Bonding Room
11. WINFertility Treatment Program Expands to Central/Southern Texas. Program Makes IVF Treatment More Affordable for Patients Without Infertility Insurance Coverage.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... ... 2017 , ... 82% of adults are unaware of the dangers that infectious bacteria play in ... minimum two times a day that dentists recommend. The ramifications of improper oral upkeep go ... and adults missing 164 million hours of work each year due to dental issues. That ...
(Date:3/23/2017)... GA (PRWEB) , ... March 23, 2017 , ... ... the release of SmartBen NOW, an innovative mobile app and centralized benefits dashboard ... and present critical information securely from multiple locations. For the first time, employees ...
(Date:3/23/2017)... ... 23, 2017 , ... The Wound Certification Prep Course ... Holdings, LLC, today announced that RestorixHealth® has officially endorsed WCPC as ... interested in becoming Certified Wound Specialist Physicians (CWSP®). , This collaborative effort ...
(Date:3/23/2017)... ... March 23, 2017 , ... March 23, 2017 - Crawford ... easily reprint customer invoices, bills, statements and other correspondence when they have been ... to retrieve and print the documents and batch them for efficient handling. ...
(Date:3/23/2017)... , ... March 23, 2017 , ... ?This conference will prominently feature 150+ Hospital and ... and Director, AMN Healthcare: Susan Salka , 43rd President of the United States ... Big Fight My Life In and Out of the Ring: Sugar Ray Leonard , ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... SANTA BARBARA, Calif. and INDIANAPOLIS ... Company (NYSE: LLY ) and the William ... improve the lives of Latino people affected by diabetes ... "The tremendous burden of diabetes and cardiovascular disease bears ... the United States ," said David Kerr ...
(Date:3/23/2017)... 23, 2017   BioSpace , the leading biotechnology ... with Indiana Biosciences Research Institute and over ... educational institutions to bring the state,s life sciences industry ... map, an artistic representation of the region,s booming biotechnology ... Vice President Mike Pence , a long-time advocate ...
(Date:3/23/2017)... -- Research and Markets has announced the addition of ... their offering. ... The global oxygen therapy devices market to grow at a CAGR ... Global Oxygen Therapy Devices Market 2017-2021, has been prepared based on ... covers the market landscape and its growth prospects over the coming ...
Breaking Medicine Technology: