Navigation Links
Feola, at University of Kentucky, receives NIH grant to study cystic fibrosis
Date:5/24/2012

LEXINGTON, Ky. (May 24, 2012) David Feola, a University of Kentucky College of Pharmacy faculty member in the Department of Pharmacy Practice and Science, received a five-year, $1.8 million grant from the National Institutes of Health (NIH) to continue his research investigating immune responses in the lungs that will potentially lead to the discovery of medical treatments for patients with cystic fibrosis and other chronic pulmonary inflammatory conditions.

Cystic fibrosis is a life-threatening disease that causes mucus in the lungs to become too thick, which leads to severe pulmonary complications. This disease is one of the most common chronic lung diseases in children and young adults, affecting 30,000 children and adults in the United States and nearly 70,000 people worldwide, according to the Cystic Fibrosis Foundation.

Feola's research lab focuses on the regulatory function of macrophages, an immune cell type that kills invading pathogens and controls inflammation, in patients with chronic pulmonary inflammatory diseases. Cystic fibrosis causes progressive, life-threatening lung damage due in large part to repeated, dysregulated inflammatory responses to bacterial infection. Preliminary research in Feola's lab suggests that inducing specific types of macrophage activation could blunt this dysregulated inflammation. This research will lead to discovery of specific drug targets that could slow or halt this destructive cycle of inflammatory injury and pulmonary function decline in these patients.

"It is our hope that this research funding will provide us a greater understanding on how cystic fibrosis works, discover novel ways of treating the disease, and how we might be able to improve quality of life for these patients," said Feola, who also is a two-time graduate of the UK College of Pharmacy. Feola received his PharmD and PhD from the College.

Feola's grant is an investigator-initiated Research Project (R01) award
'/>"/>

Contact: Allison Elliott
allison.elliott@uky.edu
University of Kentucky
Source:Eurekalert

Page: 1 2

Related medicine news :

1. McMaster University researchers discover drug destroys human cancer stem cells but not healthy ones
2. University studies and career expectations of medical students
3. University of Minnesota startup to treat challenging bacterial infection
4. Columbia University Medical Center and NY-Presbyterian experts at APA meeting
5. University of Houston Graduate College of Social Work announces partnership with MD Anderson
6. Neuropsychologist receives University of Houstons highest faculty honor
7. Louisiana Tech University professor earns NSF Early Career Development grant
8. Rice University student engineers automate limb lengthening for kids
9. Leading experts on congenital muscular dystrophy convene at University of Nevada, Reno
10. University of Cincinnati researchers win $3.7M grant from US Department of Defense
11. Oxford University Press partners with the Physical Society of Japan
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/3/2015)... Mercy Health (formerly Catholic Health Partners) – a Catholic healthcare ... of its monthly Mercy Health: Helping You Be Well videos ... disorders in the United States, affecting an estimated 16 million ... Mercy Health’s YouTube channel , Mercy Health experts explain ... you can help someone with the illness get the help ...
(Date:3/3/2015)... March 03, 2015 The physicians at ... fast weight loss product that is being recommended by ... because it contains ingredients that help people lose weight ... new combination diet product thought to possess innovative solutions ... contains three ingredients, all directed at targeting specific strategic ...
(Date:3/3/2015)... March 03, 2015 The Forbes ... covers some great ideas when planning an Eco-vacation. It ... an environmentally friendly approach. The segment will explore the ... hotel or resort’s sustainability policy, request Earth-friendly choices along ... remind viewers about how to save electricity while away. ...
(Date:3/3/2015)... March 03, 2015 First Choice ... emergency rooms in the United States, named Jeffrey Lynn ... Louetta facility. , “We are pleased to announce ... our Louetta facility,” said Dr. James M. Muzzarelli, Executive ... Dr. Smaistrla received his undergraduate and medical degrees from ...
(Date:3/3/2015)... 2015 When a lifeguard is on duty, it ... is more than just loose clothing. For a lifeguard, comfort ... public too much when the guard prefers to cover up. Comfort ... the evening and wearing the clothing that fits correctly. When ... shift, it is imperative that the guard stays warm and comfortable ...
Breaking Medicine News(10 mins):Health News:New Videos Tackle Widespread Problem of Depression 2Health News:Diet Doc Discloses the Ingredients in their Powerful New Metabolism Boost for Controlled Appetite, Fast Weight Loss and Improved Mood 2Health News:Diet Doc Discloses the Ingredients in their Powerful New Metabolism Boost for Controlled Appetite, Fast Weight Loss and Improved Mood 3Health News:Diet Doc Discloses the Ingredients in their Powerful New Metabolism Boost for Controlled Appetite, Fast Weight Loss and Improved Mood 4Health News:Forbes Living Segment on Planning an Eco-Vacation in the Works 2Health News:First Choice Emergency Room Announces Dr. Jeffrey Smaistrla as New Medical Director of LouettaFacility 2Health News:New Lifeguard Pants Introduced for those Colder Lifeguarding Days 2Health News:New Lifeguard Pants Introduced for those Colder Lifeguarding Days 3Health News:New Lifeguard Pants Introduced for those Colder Lifeguarding Days 4
... , , PRINCETON, N.J., July ... injection) can now use the insulin in their pump for ... Administration (FDA) approval of a labeling change, diabetes care company ... to be stored in the pump reservoir for two days. ...
... vaccine might fight ,tangles, of disease , WEDNESDAY, July ... two different types of brain abnormalities, both of which ... disease. , A drug called Dimebon seems to improve ... research reveals, it actually increases brain levels ...
... China, July 15 /PRNewswire-FirstCall/ - Hard to Treat Diseases ... is now preparing for the tender business of 250,000 ... and details can be viewed by visiting this web ... second completed batch exported to Indonesia this year by ...
... survey finds 3.3 percent of children aged 2 to 19 ... -- The number of underweight children aged 2 to 19 ... to 3.3 percent in 2003-2006, says a U.S. government study. ... health problems. , Researchers at the U.S. Centers for Disease ...
... , , DALLAS, July ... and practice management (PM) systems for medical practices, is now ... , , "Another company had established a ... was in place," noted Michael Nissenbaum, President and CEO of Aprima. "In ...
... cardiomyopathy , WEDNESDAY, July 15 (HealthDay News) -- Gene ... failure in some children and adults with dilated cardiomyopathy ... the most common cause of heart failure in young ... transplant -- is a condition in which the heart ...
Cached Medicine News:Health News:FDA Approves NovoLog(R) Labeling Update 2Health News:FDA Approves NovoLog(R) Labeling Update 3Health News:FDA Approves NovoLog(R) Labeling Update 4Health News:New Treatments for Alzheimer's on the Horizon 2Health News:New Treatments for Alzheimer's on the Horizon 3Health News:Hard To Treat Diseases (HTDS.PK) Tender Order To Indonesia 2Health News:'Aprima Medical Software, Inc.,' Unveiled by iMedica; Premier EHR / PM Company Adopts New Name 2Health News:'Aprima Medical Software, Inc.,' Unveiled by iMedica; Premier EHR / PM Company Adopts New Name 3Health News:Gene Mutation Is Linked to Heart Muscle Disease 2
(Date:3/3/2015)... and MENLO PARK, Calif. , ... DMPI) (DelMar and the Company), a biopharmaceutical company focused on ... indications, today announced that it will be presenting at the ... 2015, at The Ritz-Carlton, Laguna Niguel , ... Jeffrey Bacha , DelMar,s president and CEO, will ...
(Date:3/3/2015)... Calif. , March 3, 2015  STAAR Surgical Company ... marketer of implantable lenses and delivery systems for the eye, ... Officer effective immediately.  Ms. Mason, who was elected to STAAR,s ... the Board to chair the Quality and Regulatory Committee in ... as of March 1, 2015.  Ms. Mason ...
(Date:3/3/2015)... China Nepstar Chain Drugstore Ltd. (NYSE: ... drugstore chain in China based on the number of directly operated ... unaudited financial results for the fourth quarter and fiscal ... opens. The Company will host a ... 30, 2015 at 8:00 a.m. Eastern Time / 8:00 ...
Breaking Medicine Technology:DelMar Pharmaceuticals to Present at the 27th Annual ROTH Conference on March 10, 2015 2DelMar Pharmaceuticals to Present at the 27th Annual ROTH Conference on March 10, 2015 3Caren Mason Appointed President & CEO of STAAR Surgical Company 2Caren Mason Appointed President & CEO of STAAR Surgical Company 3Caren Mason Appointed President & CEO of STAAR Surgical Company 4Caren Mason Appointed President & CEO of STAAR Surgical Company 5China Nepstar Chain Drugstore to Report Fourth Quarter and Fiscal Year 2014 Financial Results on March 30, 2015 2China Nepstar Chain Drugstore to Report Fourth Quarter and Fiscal Year 2014 Financial Results on March 30, 2015 3
... Bionovo, Inc. (Nasdaq: BNVI ), a pharmaceutical company ... treatments for women,s health and cancer, today announced that Dr. ... presenting at the Cowen and Company 31st Annual Healthcare Conference ... event will be held at the Boston Marriott Copley Place, ...
... (OTCQB: CTIX) today reported that its flagship cancer compound, ... of leukemia cells in a hematopoietic xenograft tumor model. ... of p53, the "Guardian Angel" protein, which Cellceutix announced ...   The data was presented to Cellceutix ...
Cached Medicine Technology:Bionovo to Present at the Cowen and Company 31st Annual Healthcare Conference 2Cellceutix Discovers Drug Activates 'Guardian Angel p53' in Fight Against Leukemia 2Cellceutix Discovers Drug Activates 'Guardian Angel p53' in Fight Against Leukemia 3
5 mm concave jaws, cross action....
... inserter is the first of its kind. ... through a minimal incision. The special direct-acting ... bag with complete control and predictability. The ... easy around-the-clock, and the instrument has a ...
... AMO SI-30 and SI-40 foldable lenses through incisions ... for clear corneal and corneal scleral tunnels. The ... millimeter rounded blades for a secure grasp of ... have a .15 millimeter notch which may be ...
KR-8000 Supra is capable of obtaining perfectly accurate keratometry and/or refraction measurements through pupils as narrow as 2.0 mm....
Medicine Products: