Navigation Links
Femara May Beat Tamoxifen at Preventing Breast Cancer's Return
Date:10/21/2011

By Denise Mann
HealthDay Reporter

FRIDAY, Oct. 21 (HealthDay News) -- The breast cancer drug letrozole, marketed as Femara, may be more effective than tamoxifen at preventing the return of breast cancer and improving survival among older women with hormone-sensitive breast cancers, a new study reports.

In the study, published online Oct. 21 in The Lancet Oncology, the researchers updated data from an ongoing study of about 8,000 women, which compares the two drugs alone as well as the use of both Femara and tamoxifen sequentially.

Femara outperformed tamoxifen in terms of breast cancer recurrence and survival, the study found. Moreover, giving Femara alone to women was more effective than giving it sequentially following tamoxifen. The new study was partially funded by Novartis, the drug company that makes Femara.

The hormone estrogen feeds hormone-sensitive cancers, and blocking it may help stave off a recurrence. Femara is part of a class of breast cancer drugs known as aromatase inhibitors. These drugs block the body's production of estrogen via the enzyme aromatase. Tamoxifen is a selective estrogen receptor modulator, which means that it acts like estrogen in certain tissues, but not in others, namely the breast. Aromatase inhibitors are given alone or in combination with tamoxifen.

After an average eight years of follow-up, the team of researchers from the United States, Europe and Australia found that women who took Femara for five years after breast cancer treatment had a "20 percent reduced risk of their breast cancer coming back and were 21 percent less likely to die, compared with women given tamoxifen alone," one of the lead authors of the study, Meredith Regan of the Dana-Farber Cancer Institute in Boston, explained in a journal news release.

Neither sequential treatment of tamoxifen followed by Femara, or in the reverse order, significantly decreased the likelihood of re
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Paxil Blocks Tamoxifen, Lowers Survival Odds Against Breast Cancer
2. Cognitive Skills May Shrink With Tamoxifen
3. Few Women at High Risk for Breast Cancer Take Tamoxifen
4. GUMC researchers say flower power may reduce resistance to breast cancer drug tamoxifen
5. Doctors must collaborate so that patients get full benefit of tamoxifen treatment
6. Raloxifene, Tamoxifen Both Guard Against Breast Cancer
7. Cell study finds receptor can fight tamoxifen-resistant breast cancer cells
8. Gene mutation increases thromboembolism risk in women taking tamoxifen
9. Gene Mutation Offers Clues to Tamoxifen-Blood Clot Link
10. Scientists reprogram triple-negative breast cancer cells to respond to tamoxifen
11. Cough medicine could help doctors identify how breast cancer patients metabolize tamoxifen
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Femara May Beat Tamoxifen at Preventing Breast Cancer's Return
(Date:9/15/2014)... September 15, 2014 Ondine Biomedical ... Loebel, its President and Chief Technology Officer, will ... Photodynamic Therapy (PDT) and Photodiagnosis in Clinical Practice. ... Brixen/Bressanone (Italy) from October 14-18, 2014 alongside the ... on October 13-14th, is an annual conference at ...
(Date:9/15/2014)... Octo Consulting Group, a leading provider ... federal government, today announced it is opening two ... to better serve existing and future federal government ... to the strong growth momentum of the company’s ... consulting, agile software development, data visualization, and data ...
(Date:9/15/2014)... approximately one out of every 40 individuals in the United ... muscular atrophy (SMA), a neurodegenerative disease that causes muscles to ... have made a recent breakthrough with the development of a ... of the disease. In April, a patent was filed for ... lab is using to fight SMA is to ,repress the ...
(Date:9/15/2014)... Ohio (PRWEB) September 15, 2014 In ... math and medicine often act conjointly to quantify, define ... industry has become an integral part of medical care. ... regularly reports the studies conducted by the non-profit Institute ... have consistently demonstrated that math can be much more ...
(Date:9/15/2014)... Dennis Thompson HealthDay Reporter ... severe respiratory virus believed to have sickened hundreds of ... spread to the Northeast, health officials report. The ... more than a dozen cases of infection with Enterovirus ... asthma. And on Saturday, the Connecticut Department of ...
Breaking Medicine News(10 mins):Health News:Ondine Presenting at the 2014 International Symposium on Photodynamic Therapy and Photodiagnosis 2Health News:Octo Consulting Group Announces it is Opening Two New Offices in Alexandria, Virginia and Atlanta, Georgia to Better Serve Existing and Future Federal Government Clients 2Health News:Researcher develops and proves effectiveness of new drug for spinal muscular atrophy 2Health News:Math as Medicine: The Promise of Frequency Domain BioMarkers as a Template to Predict, Enchance and Promote Optimal Health 2Health News:Math as Medicine: The Promise of Frequency Domain BioMarkers as a Template to Predict, Enchance and Promote Optimal Health 3Health News:Kids' Severe Respiratory Virus Confirmed in Northeast 2Health News:Kids' Severe Respiratory Virus Confirmed in Northeast 3
... and LONDON , July 16 Since January 2009, ... awards for its work in patient education and design. In ... four 2009 Communicator Awards from the International Academy ... the company was further notified of six more awards (two ...
... , , , HOUSTON, ... first and largest provider of outsourced implantable medical device management solutions to ... chief executive officer. The appointment follows the company,s tenth quarter of ... Partners , a leading private equity firm focused exclusively on healthcare. ...
... July 16 "We,ll quit before we practice government medicine" will be ... on July 17. , , The Association ... co-sponsor the protests at the local home office of each Congressman and ... run medicine. , , Taxpayers ...
... N.Y., July 16 In an order filed on July 13, ... District of Florida appointed as Lead Counsel to the Plaintiffs, Steering ... Esq., a partner in Parker Waichman Alonso LLP, and Scott Wm. ... , Co-Lead Counsel,s responsibility is to represent ...
... , , DENVER, July 16 ... named the best respiratory hospital in the nation by U.S. News ... "We are gratified that board-certified pulmonologists around the country continue to recognize ... care," said Michael Salem, MD, President and CEO of National Jewish Health. ...
... COLUMBUS, Ohio, July 16 Mettler-Toledo International Inc. (NYSE: MTD ... Company,s second-quarter results on Thursday, July 23, 2009 at 5:00 p.m. Eastern ... www.mt.com/investors on the Company,s website. A replay of the webcast ... , METTLER TOLEDO is a leading global supplier of precision ...
Cached Medicine News:Health News:MediciGlobal Achieves Record Number of Awards 2Health News:Access MediQuip Names Tim Hargarten Chief Executive Officer 2Health News:Access MediQuip Names Tim Hargarten Chief Executive Officer 3Health News:ANDRES F. ALONSO, ESQ., a Partner in the Law Firm of PARKER WAICHMAN ALONSO LLP, Was Appointed Co-Lead Counsel to the Plaintiffs' Steering Committee in the Denture Cream Products Liability Litigation, MDL 2051 2Health News:National Jewish Health Named Top Respiratory Hospital for 12th Consecutive Year 2
(Date:9/15/2014)...  Inovio Pharmaceuticals, Inc. (NASDAQ: INO ) ... criteria for the NASDAQ Global Select Market and effective ... the NYSE MKT. The company will continue to trade ... NASDAQ Global Select Market, a segment of the NASDAQ ... any exchange in the world, requiring that strict financial, ...
(Date:9/15/2014)... Sept. 15, 2014 Research and Markets ... Pathology Market by Slide Scanners, Analytics, Delivery Modes & ... Trends to 2018" report to their offering. ... pathology market into different products and applications. Scanners accounted ... market, followed by analytics. The analytics market is expected ...
(Date:9/15/2014)... N.J. , Sept. 15, 2014   Hudson ... , in cooperation with Johns Hopkins University , ... a commercially viable high-throughput screening (HTS) system for ... Logo - http://photos.prnewswire.com/prnh/20140912/145910 This ... (ARQiv) system, will bring high-throughput screening technology into ...
Breaking Medicine Technology:Inovio Pharmaceuticals (INO) Begins Trading on NASDAQ Global Select Market Exchange 2Inovio Pharmaceuticals (INO) Begins Trading on NASDAQ Global Select Market Exchange 3Global Digital Pathology Market by Slide Scanners, Analytics, Delivery Modes & by Whole Slide Image Storage - Forecasts & Trends to 2018 2Global Digital Pathology Market by Slide Scanners, Analytics, Delivery Modes & by Whole Slide Image Storage - Forecasts & Trends to 2018 3Hudson Robotics and Johns Hopkins Receive NIH Grant for Zebrafish HTS System 2
Inquire...
... of electronic refractors. The TRS replaces your standard ... a keypad that is small enough to sit in ... Chart Projector. The TRS is programmable so that at ... moved for you, taking you to your next refraction ...
Uniquely designed, the wheelchair table has dual purposes. Not only does it add a modern look to any office, it is also a heavy-duty table that will support multiple instruments, and/or easily accomm...
... Ideal for satellite clinics or for ... value, the Debut stand is an ... construction and molded composite body offer ... counterbalanced slit-lamp arm--one of two arms ...
Medicine Products: