Navigation Links
Female Hormones Deter Salt-Sensitive Hypertension
Date:2/6/2009

Estrogen appears to improve kidneys' ability to shed sodium, study says

FRIDAY, Feb. 6 (HealthDay News) -- Hormones and a cell receptor in the kidneys may explain why premenopausal women have fewer problems than men with salt-sensitive hypertension, a new study says.

Salt-sensitive hypertension occurs when the kidneys hold onto more sodium than necessary. This drives up blood pressure as the body tries to force the kidneys to get rid of excess salt. Endothelin B (ETB) receptors, found in the blood vessels and tubules of the kidney, are thought to act as gatekeepers, deciding how much salt the body should excrete.

"We know from other studies we have done that this endothelin B receptor is critical to keeping you from becoming hypertensive when you eat salt," investigator Dr. David Pollock, a renal physiologist in the Vascular Biology Center at the Medical College of Georgia, said in a news release issued by the university.

However, endothelin A (ETA) receptors counteract their siblings' work by signaling when to increase blood pressure. ETA antagonist drugs, which block the receptors, are already used to control pulmonary hypertension.

Tests on rats showed ETA receptors do not reduce blood flow to the kidneys in female rats as much as they do to male rats. Instead, they actually increase sodium output without increasing blood pressure.

When researchers removed the ovaries of the female rats, they responded more like the males. Estrogen, Pollack said, appeared to improve the action of the ETA receptors.

The findings were published in the February issue of Hypertension.

The researchers plan more studies into different receptor subtypes. Meanwhile, colleagues at the University of Edinburgh in Scotland have begun studying how ETA receptor blockers may impact sodium excretion.

More information

The American Heart Association has more about hypertension.



-- Kevin McKeever



SOURCE: Medical College of Georgia, news release, Jan. 28, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. The Female Health Company Schedules First Quarter Conference Call for February 10, 2009
2. Living with females extends the reproductive life of the male mouse, says Penn veterinary researcher
3. FDA Advisory Committee Votes Unanimously that FC2 Female Condom(R) is Approvable
4. Surprising Results on Smoking Research Hispanic Versus White Female Smokers
5. Latin American and U.S. Latina Women Unite to Demand Access to the Female Condom
6. The Female Health Company Schedules Year End FY2008 Conference Call for December 1, 2008
7. Surprisingly, female models have negative effect on men
8. Large-Scale Survey Reveals Low Sexual Desire Most Common Distressing Female Sexual Problem, Affecting Up to One in 10 Women
9. Sexual Trauma Haunts Many Female Vets
10. The Health Insurance Advocate Radio Show Expands to Springfield, Missouri, and Reaches a New All-Time Ratings High for Female Listenership
11. Reese Witherspoon Visits Brazil to Spread Message of Female Empowerment as Avons Global Ambassador
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Female Hormones Deter Salt-Sensitive Hypertension
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Apple ... care services, staged a mock evacuation of the facility as part of a disaster ... Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well as the ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Global Healthcare Management’s ... Alexandria Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s ... The fun run is geared towards children of all ages; it is a ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the ... danger possible to save lost souls in the Philippines. “The Journey: From the Mountains ... a dedicated teacher of the Bible. She has taught all ages and currently teaches ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and ... plans to open a flagship location in Covington, LA at 401 N. U.S. Highway ... store next to Office Depot in the Holiday Square shopping center. Its location allows ...
(Date:10/12/2017)... ... 2017 , ... Asante, a nationally recognized health system in ... existing home health joint venture through an agreement, effective October 1, 2017, to ... home health company with Asante, delivering clinically integrated care, for the past eight ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... -- NDS received FDA 510(k) clearance in May 2017 for its highly ... designed for endoscopy environments. An innovative secondary monitor solution, ZeroWire ... support the improvement of patient outcomes, procedural efficiency, and the lowering ... ... ...
(Date:10/4/2017)... 4, 2017  South Korean-based healthcare product Development Company ... "cprCUBE" on Kickstarter. The device will educate the user ... with better efficiency compared to the dated and pricey ... on efficacy of the compression for a more informed ... goal to raise $5,000. ...
(Date:10/2/2017)... 2017  Eli Lilly and Company (NYSE: ... third quarter of 2017 on Tuesday, October 24, 2017. ... day with the investment community and media to further ... call will begin at 9 a.m. Eastern time. Investors, ... webcast of the conference call through a link that ...
Breaking Medicine Technology: