Navigation Links
Female Hormones Deter Salt-Sensitive Hypertension
Date:2/6/2009

Estrogen appears to improve kidneys' ability to shed sodium, study says

FRIDAY, Feb. 6 (HealthDay News) -- Hormones and a cell receptor in the kidneys may explain why premenopausal women have fewer problems than men with salt-sensitive hypertension, a new study says.

Salt-sensitive hypertension occurs when the kidneys hold onto more sodium than necessary. This drives up blood pressure as the body tries to force the kidneys to get rid of excess salt. Endothelin B (ETB) receptors, found in the blood vessels and tubules of the kidney, are thought to act as gatekeepers, deciding how much salt the body should excrete.

"We know from other studies we have done that this endothelin B receptor is critical to keeping you from becoming hypertensive when you eat salt," investigator Dr. David Pollock, a renal physiologist in the Vascular Biology Center at the Medical College of Georgia, said in a news release issued by the university.

However, endothelin A (ETA) receptors counteract their siblings' work by signaling when to increase blood pressure. ETA antagonist drugs, which block the receptors, are already used to control pulmonary hypertension.

Tests on rats showed ETA receptors do not reduce blood flow to the kidneys in female rats as much as they do to male rats. Instead, they actually increase sodium output without increasing blood pressure.

When researchers removed the ovaries of the female rats, they responded more like the males. Estrogen, Pollack said, appeared to improve the action of the ETA receptors.

The findings were published in the February issue of Hypertension.

The researchers plan more studies into different receptor subtypes. Meanwhile, colleagues at the University of Edinburgh in Scotland have begun studying how ETA receptor blockers may impact sodium excretion.

More information

The American Heart Association has more about hypertension.



-- Kevin McKeever



SOURCE: Medical College of Georgia, news release, Jan. 28, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. The Female Health Company Schedules First Quarter Conference Call for February 10, 2009
2. Living with females extends the reproductive life of the male mouse, says Penn veterinary researcher
3. FDA Advisory Committee Votes Unanimously that FC2 Female Condom(R) is Approvable
4. Surprising Results on Smoking Research Hispanic Versus White Female Smokers
5. Latin American and U.S. Latina Women Unite to Demand Access to the Female Condom
6. The Female Health Company Schedules Year End FY2008 Conference Call for December 1, 2008
7. Surprisingly, female models have negative effect on men
8. Large-Scale Survey Reveals Low Sexual Desire Most Common Distressing Female Sexual Problem, Affecting Up to One in 10 Women
9. Sexual Trauma Haunts Many Female Vets
10. The Health Insurance Advocate Radio Show Expands to Springfield, Missouri, and Reaches a New All-Time Ratings High for Female Listenership
11. Reese Witherspoon Visits Brazil to Spread Message of Female Empowerment as Avons Global Ambassador
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Female Hormones Deter Salt-Sensitive Hypertension
(Date:6/26/2016)... Michigan (PRWEB) , ... June 26, 2016 , ... On ... as sponsor of the 2016 Cereal Festival and World’s Longest Breakfast Table in Battle ... honor of the city’s history as home to some of the world’s leading providers ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... ... health policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, ... work on several important health care topics including advance care planning, healthcare costs ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... As a ... Magna Cum Laude and his M.D from the David Geffen School of Medicine at ... returned to Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars ...
(Date:6/24/2016)... ... ... Those who have experienced traumatic events may suffer from a complex set of ... or alcohol abuse, as a coping mechanism. To avoid this pain and suffering, Serenity ... event. , Trauma sufferers tend to feel a range of emotions, from depression, guilt, ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas of ... AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016 Any dentist who has made an implant ... process. Many of them do not even offer this as ... high laboratory costs involved. And those who ARE able to ... a high cost that the majority of today,s patients would ... Parsa Zadeh , founder of Dental Evolutions Inc. and inventor ...
(Date:6/23/2016)... 2016 Research and Markets has announced ... Analysis 2016 - Forecast to 2022" report to their ... contains up to date financial data derived from varied research ... trends with potential impact on the market during the next ... which comprises of sub markets, regional and country level analysis. ...
(Date:6/23/2016)... , June 23, 2016 , ... on Thursday, July 7, 2016 , , , , LOCATION: ... , , , , EXPERT PANELISTS:  , , , ... Senior Industry Analyst, Christi Bird; Senior Industry Analyst, Divyaa Ravishankar and ... The global pharmaceutical industry is witnessing an exceptional era. ...
Breaking Medicine Technology: