Navigation Links
Feinstein Institute Researcher provides insight into osteoarthritis
Date:4/19/2013

MANHASSET, NY A researcher at The Feinstein Institute for Medical Research has discovered additional mechanical properties of articular cartilage, a protective cartilage on the ends of bones that wears down over time, resulting in the development of osteoarthritis. The findings are published in the April issue of PLOS ONE.

To better understand the onset and progression of osteoarthritis, Nadeen Chahine, PhD, and collaborators at other institutions looked at cells from articular cartilage using atomic force microscopy (AFM). They used this technology to measure the mechanical properties of single cells to uncover what gives them integrity versus what wears them down with aging. They found in animal models that the mechanical properties of the cells are higher in adult tissue compared to young or old tissue, which is consistent with the higher loads on joints in adults than joints in infants. Furthermore, they found that vimentin, an intermediate filament (IF) protein, is a key contributor to the integrity of the cells.

"This research is exciting because we are using cutting-edge instrumentation to understand the mechanobiology of cells and cartilage, and what might cause or prevent osteoarthritis," said Nadeen Chahine, PhD, director of the Bioengineering-Biomechanics Laboratory at the Feinstein Institute. "Osteoarthritis is the most common form of arthritis, and patients who suffer from the disease experience joint pain, tenderness, stiffness and locking.

It is my hope that this and additional research into articular cartilage will provide insight into how we may be able to alleviate these disruptive symptoms of osteoarthritis through innovative research at the interface of mechanics and biology."


'/>"/>

Contact: Emily Eng
eng3@nshs.edu
516-562-2670
North Shore-Long Island Jewish (LIJ) Health System
Source:Eurekalert

Page: 1

Related medicine news :

1. Feinstein Institute Scientist Wins Crafoord Award from Royal Swedish Academy of Sciences for Arthritis Research
2. A Feinstein Institute for Medical Research Study Shows Early Cognitive Problems among Those Who Eventually Get Alzheimer's
3. Feinstein Institute researchers discover plant derivative
4. Feinstein announces submission of new drug application for diagnosing parkinsonian syndromes
5. Feinstein Institute researchers discover that bean used in Chinese food could protect against sepsis
6. Feinstein Institute to Receive Grant from Centers for Medicare & Medicaid Services to Improve Schizophrenia Treatment
7. Feinstein Institute to receive grant to improve schizophrenia treatment
8. La Jolla Institutes surprising finding could alter the face of dengue vaccine development
9. Spencer Institute’s Mind Body Fitness Certification Integrates Best of Mental and Physical Training to Promote Healthy Living
10. Spencer Institute Lifestyle Fitness Coach Certification Combines Life Coaching and Fitness Coaching in One Powerful Online Training
11. MGH Neurological Clinical Research Institute and Prize4Life receive Bio-IT World award
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/4/2016)... York, NY (PRWEB) , ... December 03, 2016 ... ... largest non-profit organization devoted exclusively to funding innovative lymphoma research and serving the ... services – hosted its first Swirl: A Wine Tasting Event in New York ...
(Date:12/4/2016)... , ... December 03, 2016 , ... While James Earl ... serving as host for in a show called "Front Page". One of the forthcoming ... years, breast cancer rates have plummeted in large part due to early detection. Like ...
(Date:12/4/2016)... Dallas, TX (PRWEB) , ... December 03, 2016 ... ... of the “Fastest growing Entrepreneurial Company in the Dallas area” Tuesday evening at ... the Omni Dallas Hotel, presented by SMU's Cox School’s Caruth Institute for Entrepreneurship. ...
(Date:12/4/2016)... , ... December 04, 2016 , ... ... major cosmetic surgery can now take advantage of a cosmetic procedure known as ... rejuvenation treatment that reduces the appearance of age spots, fine lines, uneven ...
(Date:12/4/2016)... (PRWEB) , ... December 04, 2016 , ... Responsible dental ... One must brush properly to achieve optimal results. This important necessity inspired an inventor ... need for a way to ensure that people break or avoid bad techniques of ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... the largest share in the ECG Cables And ECG Leadwires ... remote monitoring ECG devices. On the other hand, the ... the highest growth rate during the forecast period. ... Company (U.S.), Medtronic plc ( Ireland ), Koninklijke ... Medical International Limited ( China ), held major ...
(Date:12/2/2016)... Research and Markets has announced the addition of the "Global ... report to their offering. ... , The global ultrasound device market ... to grow at a CAGR of 5.5% during 2016-2022. Based on portability, ... forecast period, a CAGR of 8.8% in the global market. Among the ...
(Date:12/2/2016)... , Dec. 2, 2016  PipelineRx, a leading medication ... be offering demonstrations of its SaaS-based telepharmacy platform, ... Health-System Pharmacists 2016 Midyear Clinical Meeting and Exhibition, ... . With nearly 300 hospital clients nationally, the ... technology designed to dramatically improve pharmacy operations, enhance ...
Breaking Medicine Technology: