Navigation Links
Feinstein Institute Researcher provides insight into osteoarthritis
Date:4/19/2013

MANHASSET, NY A researcher at The Feinstein Institute for Medical Research has discovered additional mechanical properties of articular cartilage, a protective cartilage on the ends of bones that wears down over time, resulting in the development of osteoarthritis. The findings are published in the April issue of PLOS ONE.

To better understand the onset and progression of osteoarthritis, Nadeen Chahine, PhD, and collaborators at other institutions looked at cells from articular cartilage using atomic force microscopy (AFM). They used this technology to measure the mechanical properties of single cells to uncover what gives them integrity versus what wears them down with aging. They found in animal models that the mechanical properties of the cells are higher in adult tissue compared to young or old tissue, which is consistent with the higher loads on joints in adults than joints in infants. Furthermore, they found that vimentin, an intermediate filament (IF) protein, is a key contributor to the integrity of the cells.

"This research is exciting because we are using cutting-edge instrumentation to understand the mechanobiology of cells and cartilage, and what might cause or prevent osteoarthritis," said Nadeen Chahine, PhD, director of the Bioengineering-Biomechanics Laboratory at the Feinstein Institute. "Osteoarthritis is the most common form of arthritis, and patients who suffer from the disease experience joint pain, tenderness, stiffness and locking.

It is my hope that this and additional research into articular cartilage will provide insight into how we may be able to alleviate these disruptive symptoms of osteoarthritis through innovative research at the interface of mechanics and biology."


'/>"/>

Contact: Emily Eng
eng3@nshs.edu
516-562-2670
North Shore-Long Island Jewish (LIJ) Health System
Source:Eurekalert

Page: 1

Related medicine news :

1. Feinstein Institute Scientist Wins Crafoord Award from Royal Swedish Academy of Sciences for Arthritis Research
2. A Feinstein Institute for Medical Research Study Shows Early Cognitive Problems among Those Who Eventually Get Alzheimer's
3. Feinstein Institute researchers discover plant derivative
4. Feinstein announces submission of new drug application for diagnosing parkinsonian syndromes
5. Feinstein Institute researchers discover that bean used in Chinese food could protect against sepsis
6. Feinstein Institute to Receive Grant from Centers for Medicare & Medicaid Services to Improve Schizophrenia Treatment
7. Feinstein Institute to receive grant to improve schizophrenia treatment
8. La Jolla Institutes surprising finding could alter the face of dengue vaccine development
9. Spencer Institute’s Mind Body Fitness Certification Integrates Best of Mental and Physical Training to Promote Healthy Living
10. Spencer Institute Lifestyle Fitness Coach Certification Combines Life Coaching and Fitness Coaching in One Powerful Online Training
11. MGH Neurological Clinical Research Institute and Prize4Life receive Bio-IT World award
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... ... , ... Viewers who like to educate themselves on current issues and who ... and societal issues tend to appreciate and love the "Informed" series, hosted by Rob ... events for causes around the world. , Running for charity has become ...
(Date:3/24/2017)... (PRWEB) , ... March 24, 2017 , ... ... the first Certified Medical Reiki™ Master in Frederick, MD. Judy says, “I am ... caregivers during what is often a very difficult and challenging time.” , A ...
(Date:3/24/2017)... ... March 24, 2017 , ... “Vintage and Harvest A Cultivation of Christian Love” ... teacher residing in North Carolina with his wife, Anna Marie. He and his wife ... grandchildren. David is also the author of “Shadow and Substance.” , “Love, the agape ...
(Date:3/23/2017)... WA (PRWEB) , ... March 23, 2017 , ... In ... and now estimates that there could be four million Zika-related cases in the Americas ... date with numbers of US cases reported per year skyrocketing to an estimated 329,000. ...
(Date:3/23/2017)... ... March 23, 2017 , ... Demonstrating their commitment to improving ... health departments have been awarded national accreditation through the Public Health Accreditation ... expanding network of communities across the nation whose health departments meet rigorous national ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... 2017 Research and Markets has announced ... Consumer Strategies" report to their offering. ... Pain Management in ... treat their physical pain, emphasizing consumer survey analysis, including trends ... and adults who have selected illnesses/conditions strongly associated with physical ...
(Date:3/24/2017)... FinancialBuzz.com News Commentary   ... Medical cannabis products around the world are projected to ... global medical cannabis market will reach a value of USD 55.8 billion ... for the new growing industry. By the end of 2016, 28 states ... medical cannabis. More conservative states like Arkansas and ...
(Date:3/24/2017)... 24, 2017 Today Stock-Callers.com have issued ... are: Neovasc Inc. (NASDAQ: NVCN), Hologic Inc. (NASDAQ: HOLX), Edwards ... SSH ). These companies are part of the Healthcare ... Thursday, March 23 rd , 2017, with the NYSE Health ... health care companies in the S&P 500 were down about ...
Breaking Medicine Technology: