Navigation Links
Fat molecule ceramide may factor in muscle loss in older adults
Date:10/31/2012

As men and women age, increasing quantities of fat tissue inevitably take up residence in skeletal muscle. A small study of older and younger men conducted at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University suggests that a build-up of a fat molecule known as ceramide might play a leading role in muscle deterioration in older adults. The results of the study were published online this month by the Journal of Applied Physiology, a publication of the American Physiological Society.

The study enrolled ten 10 men in their mid-seventies to nine men in their early twenties. None of the men carried excess weight or had chronic health problems and none had exercised in six months. Ceramide was measured in a muscle biopsy taken at baseline. The participants performed a single bout of exercise (three sets of ten repetitions of knee extensions and leg presses) followed by two muscle biopsies which the authors used to examine how the exercise impacted muscle growth response.

"There is a known relationship between elevated ceramide levels and unhealthy muscle in obese adults, but to the best of our knowledge, this had not been studied in healthy weight, older adults," said Donato Rivas, Ph.D., the study's first author and a scientist in the Nutrition, Exercise Physiology and Sarcopenia Laboratory at the USDA HNRCA at Tufts University. "Our analysis of the muscle biopsies showed an accumulation of two types of ceramide molecules containing saturated fatty acids that were 156% and 30% higher in the older men. Furthermore, having higher accumulation of one of these saturated fatty acid types was associated with having less leg muscle mass in both younger and older men."

"Although it is well known that fat tissue replaces some of our muscle tissue as we grow older, we are seeking to understand whether some fat molecules are more damaging to muscle than others," said Roger A. Fielding, Ph.D., senior author and
'/>"/>

Contact: Andrea Grossman
617-636-3728
Tufts University, Health Sciences Campus
Source:Eurekalert

Page: 1 2

Related medicine news :

1. New developments reveal a molecule with a promising function in terms of cancer treatment.
2. Measuring molecules with the naked eye
3. Molecule shows effectiveness against drug-resistant myeloma
4. Molecule found that inhibits recovery from stroke
5. Cleveland Clinic researchers discover molecule that may prevent atherosclerosis
6. Mayo Clinic: Molecule thought cancer foe actually helps thyroid tumors grow
7. Inhibitors of shuttle molecule show promise in acute leukemia
8. Researchers identify a life-and-death molecule on chronic leukemia cells
9. Prions in the brain eliminated by homing molecules
10. Molecule movements that make us think
11. Smoking and hyperactivity share common genetic risk factor
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/2/2015)... 02, 2015 Visiting Nurse Association ... of home health care, hospice and community services, ... CEO, Steve Landers, MD, MPH, to the Visiting ... , VNAA is a national association based ... mission driven, nonprofit providers of home and community-based ...
(Date:6/2/2015)... OH (PRWEB) June 02, 2015 Mercy ... ministry serving Ohio and Kentucky – has devoted the ... Well videos to skin cancer prevention. One in five ... video on Mercy Health’s YouTube channel, a Mercy Health ...     What are the main causes of skin cancer? , ...
(Date:6/2/2015)... First Choice Emergency Room , ... the United States, named Kenneth Alan Totz, D.O.as the ... facility. , “We are pleased to announce Dr. ... said Dr. James M. Muzzarelli, Executive Medical Director of ... his undergraduate degree from St. Edwards University in Austin, ...
(Date:6/2/2015)... Phoenix, AZ (PRWEB) June 02, 2015 ... Iowa community, has granted $70,000 to the UNMC to support ... NFL Kicker Billy Cundiff, a member of the Colleen’s Dream ... grant was the biggest to date for Colleen’s Dream ... Dr. Wang in Omaha. , “Dr. Wang is a rising ...
(Date:6/2/2015)... IL (PRWEB) June 02, 2015 While ... action adaptions of comic books, comic books themselves are ... , Comics Uniting Nations plans to produce educational comics ... forthcoming Global Goals for Sustainable Development - an international ... extreme poverty, hunger, health, education, sustainable energy, inequality, climate ...
Breaking Medicine News(10 mins):Health News:Steve Landers, MD, MPH, President and CEO of VNA Health Group Appointed to VNAA Board of Directors 2Health News:Steve Landers, MD, MPH, President and CEO of VNA Health Group Appointed to VNAA Board of Directors 3Health News:Video provides helpful information about skin cancer prevention 2Health News:First Choice Emergency Room Announces Dr. Kenneth Alan Totz as New Medical Director of Houston – Jones Road Facility 2Health News:Colleen’s Dream Foundation Grants $70,000 to the University of Nebraska Medical Center (UNMC) to Support Ovarian Cancer Research 2Health News:Colleen’s Dream Foundation Grants $70,000 to the University of Nebraska Medical Center (UNMC) to Support Ovarian Cancer Research 3Health News:Can Comics Help the United Nations Save the World? 2Health News:Can Comics Help the United Nations Save the World? 3
... announced that they have created a computer tool ... microbicides// used by women for preventing HIV infections. ... infections globally are soaring. ,By applying ... a computer model that can predict the effectiveness ...
... Research Hospital have discovered that a protein called ABCB6 plays ... key to the ability// of red blood cells to carry ... cells to extract energy from nutrients. ,The St. ... membrane of the cell’s energy powerhouse called the mitochondria; and ...
... on par with other children from single births for ... has been found wanting and they fared less better ... twins receive less attention from parents as well as ... of 11,000 youngsters shows that twins are catching up. ...
... the good news: Suicide rates among younger and older Americans ... news: No one really knows why// . ,Those ... the University of South Carolina and released Thursday (Sept. 28) ... Health. ,Dr. Robert McKeown, a professor and associate ...
... by scientists at the Broad Institute of MIT and Harvard ... “roadmap” that can connect human diseases// with potential drugs to ... in human cells. Called the 'Connectivity Map,' the new tool ... of Science and in separate publications in the September 28 ...
... faculty members performing microsurgery in Tanzania from a computer ... experts// in Vietnam presenting an avian influenza patient to ... are some of the possible applications of a high-tech ... first time next week to link Johns Hopkins faculty ...
Cached Medicine News:Health News:Computer Tool Predicts Effectiveness Of Microbicides 2Health News:Computer Tool Predicts Effectiveness Of Microbicides 3Health News:ABCB6 Is Key to Production of Heme in Hemoglobin 2Health News:Most Suicide Rates Decline, but Findings Are Puzzling 2Health News:Most Suicide Rates Decline, but Findings Are Puzzling 3Health News:Genetic 'Roadmap' Charts Links Between Drugs and Human Disease 2Health News:Genetic 'Roadmap' Charts Links Between Drugs and Human Disease 3Health News:High-Speed Internet2 Link Revolutionizes Global Medical Education 2
(Date:6/2/2015)... 2015  BD (Becton, Dickinson and Company) (NYSE: ... company, today announced its participation in the White ... steps the company will take to help combat ... full range of expertise related to identification and ... information to electronic surveillance and prevention of health ...
(Date:6/2/2015)... 2015 Northstar Global Business Services, Inc. ... commercial advertisement, which it plans to use in ... company,s top selling product. The advertisement ... with television advertising. Previous ads focused on a ... version takes an entertainment-oriented path, and uses one ...
(Date:6/2/2015)... MADRID , June 2, 2015 /PRNewswire/ ... meeting annuale della American Society of Clinical Oncology    ... multicentrico di fase 3 SAR3007, resi noti dal dipartimento ... hanno evidenziato un significativo miglioramento della sopravvivenza libera da ... ) rispetto al trattamento con dacarbazina in pazienti con ...
Breaking Medicine Technology:BD Participates in White House Forum on Antibiotic Stewardship 2BD Participates in White House Forum on Antibiotic Stewardship 3Northstar releases its direct response multi-media ad designed to be used in national television advertising campaigns 2PharmaMar annuncia che lo studio di Janssen ha evidenziato che la trabectedina migliora il controllo della malattia in pazienti con sarcoma dei tessuti molli in stato avanzato 2PharmaMar annuncia che lo studio di Janssen ha evidenziato che la trabectedina migliora il controllo della malattia in pazienti con sarcoma dei tessuti molli in stato avanzato 3PharmaMar annuncia che lo studio di Janssen ha evidenziato che la trabectedina migliora il controllo della malattia in pazienti con sarcoma dei tessuti molli in stato avanzato 4PharmaMar annuncia che lo studio di Janssen ha evidenziato che la trabectedina migliora il controllo della malattia in pazienti con sarcoma dei tessuti molli in stato avanzato 5PharmaMar annuncia che lo studio di Janssen ha evidenziato che la trabectedina migliora il controllo della malattia in pazienti con sarcoma dei tessuti molli in stato avanzato 6
... 2011 Milestone Scientific Inc. (OTCQB: MLSS), the recognized leader ... the year ended December 31, 2010. Financial ... Ended December 31, 2009: Total revenues were ... the U.S. decreased 16% to $4.53 million from $5.28 million. ...
... 4, 2011 MonoSol Rx, the developers of PharmFilm® ... pharmaceutical film products, today announced that it has been ... Patent and Trademark Office (USPTO). The patent provides intellectual ... preparation along with the incorporation of specific drugs and ...
Cached Medicine Technology:Milestone Scientific Announces 2010 Year End Results 2Milestone Scientific Announces 2010 Year End Results 3Milestone Scientific Announces 2010 Year End Results 4Milestone Scientific Announces 2010 Year End Results 5Milestone Scientific Announces 2010 Year End Results 6MonoSol Rx Issued Strategic US Patent Governing the Production of Pharmaceutical Films Containing Specific Drugs and Drug Classes 2MonoSol Rx Issued Strategic US Patent Governing the Production of Pharmaceutical Films Containing Specific Drugs and Drug Classes 3
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: