Navigation Links
Fat in Males, Females Differs Genetically, Mouse Study Shows
Date:5/20/2010

Finding might explain why men store fat around belly, women around the hips

THURSDAY, May 20 (HealthDay News) -- Male fat tissue and female fat tissue are genetically distinct from one another, new research on lab animals reveals.

The observation -- based on work conducted solely with mice -- might explain why men tend to store fat in their bellies, while women tend to pile it on their hips.

Researchers from UT Southwestern Medical Center explored the question by focusing on the fat distribution patterns of mice, which are similar to those of people. Genes were taken from the belly and hip fat of male mice and female mice, as well as from female mice whose ovaries had been removed to mimic human female menopause.

A genetic comparison of the removed fat cells revealed that out of approximately 40,000 mouse genes, only 138 were common to both genders.

"This was completely unexpected," Dr. Deborah Clegg, UTSMC senior author and assistant professor of internal medicine, said in a news release. "We expected the exact opposite -- that 138 would be different and the rest would be the same between the sexes."

Clegg and her colleagues note that men tend to carry excess weight around their gut area, while pre-menopausal women are more likely to carry it around their butt, hips, and thighs. After menopause, stored fat in women then shifts to the waist area, following a drop in ovarian hormone levels.

Aside from genetic differences, fat tissue also seemed to differ in other basic ways, as male mice fed a high-fat diet for 12 weeks gained more weight than similarly fed female mice. Male fat tissue also seemed more prone to inflammation than female fat tissue, the authors noted.

On the other hand, female mice whose ovaries had been removed started to exhibit weight gain and inflammation patterns similar to those of the male mice.

The findings led the research team to suggest that ovarian hormones play a critical role in where fat gets deposited in women.

The finding is reported in the current issue of the International Journal of Obesity.

More information

For more on body fat, visit the American Heart Association.



-- Alan Mozes



International Journal of Obesity, May 14, 2010, news release.


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. College Age Females Can Kiss Chlamydia Goodbye for Valentines Day
2. Beating Heart Differs by Gender, Age: Study
3. New UCSF Studies Reveal that Age-Related Nerve Decline is Associated with Inflammation and Differs by Gender
4. Association of fiber and colorectal cancer risk differs depending on dietary assessment method
5. Substance Abuse in Mexican Americans Differs by Gender
6. Scientists Turn Mouse Skin Cells Into Nerve Cells
7. ALPCO Announces the Launch of Rat and Mouse Proinsulin ELISA Kits
8. Mouse Study May Advance Multiple Sclerosis Research
9. Schizophrenia mouse model should improve understanding and treatment of the disorder
10. Rapamycin rescues learning, memory in Alzheimers mouse model
11. NIA researchers find gene to explain mouse embryonic stem cell immortality
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... , ... June 24, 2016 , ... Marcy was in a crisis. Her son James, ... out at his family verbally and physically. , “When something upset him, he couldn’t control ... use it. He would throw rocks at my other children and say he was going ...
(Date:6/24/2016)... ... ... Comfort Keepers® of San Diego, CA is excited to announce they are ... drive cancer patients to and from their cancer treatments. Comfort Keepers provides quality ... and ongoing independence. Getting to and from medical treatments is one of the ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... is proud to recognize Dr. Barry M. Weintraub as a prominent plastic surgeon ... beautiful women in the world, and the most handsome men, look naturally attractive. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Venture Construction Group (VCG) sponsors Luke’s ... June 20th at the Woodmont Country Club at 1201 Rockville Pike, Rockville, Maryland, 20852. ... helping service members that have been wounded in battle and their families. Venture Construction ...
(Date:6/24/2016)... ... 2016 , ... To succeed under value-based payments, healthcare providers ... how to move forward, given the need to sustain current operations. PYA has ... an organization’s specific needs. , PYA Principal Martie Ross states, “Healthcare providers want ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... PRINCETON, N.J. , June 23, 2016  Guerbet ... of Premier Inc.,s Supplier Horizon Award . ... this year, Guerbet was recognized for its support of ... value creation through clinical excellence, and commitment to lower ... delighted to receive this recognition of our outstanding customer ...
(Date:6/23/2016)... , June 23, 2016  Experian ... integrating and transforming the patient payment and ... several innovative new products and services that ... its revenue cycle offerings. These award-winning solutions ... efficient workflows, remain compliant in an ever-changing ...
(Date:6/23/2016)... DIEGO , June 23, 2016 ... programs that address medical conditions resulting from a ... it has appointed Greg Doyle as ... of Leading BioSciences, executive management team and board ... and chief financial officer. He will provide continued ...
Breaking Medicine Technology: