Navigation Links
Fat Cells in Obese People Are 'Sick'
Date:8/27/2008

More likely to make insulin-resistant proteins, study says

WEDNESDAY, Aug. 27 (HealthDay News) -- Fat cells in obese people are "sick" compared to those in lean people, a new study shows.

Published in the September issue of Diabetes, a group of researchers from the Temple University School of Medicine analyzed fat samples from the upper thighs of six lean and six obese people.

They found significant differences in the fat cells of the obese participants compared with the lean participants.

"The fat cells we found in our obese patients were deficient in several areas," study author Guenther Boden, the Laura H. Carnell Professor of Medicine and chief of endocrinology, said in Temple press release.

Boden said that the obese people's fat cells showed stress on the endoplasmic reticulum (ER), which helps cells synthesize proteins and monitor how they are folded. When the ER is stressed, Boden explained, it produces several proteins that ultimately lead to insulin resistance. Insulin resistance, in turn, plays a major role in the development of obesity-related conditions.

The differences in the fat cells between obese and lean people may help explain the link between obesity and a higher risk of diabetes, heart disease, and stroke, Boden theorized.

More information

The National Heart, Lung, and Blood Institute has more about overweight and obesity.



-- Krisha McCoy



SOURCE: Temple University, news release, Aug. 27, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Pancreatic Cells Turned Into Insulin-Producing Beta Cells
2. UNC researcher aims to unmask cancer cells to trigger bodys immune system
3. Bone marrow stem cells may help control inflammatory bowel disease
4. By amplifying cell death signals, scientists make precancerous cells self-destruct
5. Researchers Hunt Normal Cells That Give Rise to Cancer
6. Childhood brain tumor traced to normal stem cells gone bad
7. B Cells Can Act Alone in Autoimmune Diseases
8. Key to virulence protein entry into host cells discovered
9. Methadone Kills Resistant Leukemia Cells
10. Scientists Turn Skin Cells Into Motor Neurons in ALS Patients
11. Protein made by fat cells may increase risk of heart attack in older adults
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/12/2016)... Middletown, PA (PRWEB) , ... February 12, 2016 , ... ... year’s event will be held in Anaheim, CA at the Anaheim Convention Center. Almost ... they can see new therapy products in action, learn more about their chosen field ...
(Date:2/12/2016)... , ... February 12, 2016 , ... ... announced that nominations have closed for the ISE Southeast Awards 2016. Finalists and ... announced at the ISE® Southeast Executive Forum and Awards Gala on March 15, ...
(Date:2/12/2016)... ... February 12, 2016 , ... Every winter, someone is killed, injured or loses ... Penn Burn Center, part of the Allegheny Health Network, has partnered with Etna ... “Space Heaters Need Space” campaign. , “Space Heaters Need Space” aims to ...
(Date:2/12/2016)... ... February 12, 2016 , ... The Jones Agency, a family owned insurance company ... launching a cooperative charity drive with the Tarrant Area Food Bank in the hopes ... and families in need, the Tarrant County Food Bank offers hope and security to ...
(Date:2/12/2016)... ... 2016 , ... Young Asset Protection, a full service insurance ... latest charity campaign in their community enrichment program. Art Expression utilizes after-school programs ... are currently being accepted at: http://artexpressioninc.org/ . , Art Expression is a ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... --> ... Global Clinical Trials Review, H2, 2015 provides an ... trials landscape along with top level data related ... & E7), Trial Status, Trial Phase, Sponsor Type ... involved and enlists all trials (Trial title, Phase, ...
(Date:2/11/2016)... 2016 The primary goal of this research ... on the usage of liquid biopsy. Key information the ... - Timeframe of liquid biopsy adoption amidst future users ... organization type - Sample inflow to conduct liquid biopsy ... serum, and so on. - Correlation analysis of sample ...
(Date:2/11/2016)... IRVINE, Calif., Feb. 11, 2016 PRO-DEX, INC. (NasdaqCM: ... quarter ended December 31, 2015. The Company also filed its ... fiscal year 2016 with the Securities and Exchange Commission today. ... December 31, 2015 --> --> ... 2015 increased $2.6 million, or 95%, to $5.4 million from ...
Breaking Medicine Technology: