Navigation Links
Fat Cells in Obese People Are 'Sick'
Date:8/27/2008

More likely to make insulin-resistant proteins, study says

WEDNESDAY, Aug. 27 (HealthDay News) -- Fat cells in obese people are "sick" compared to those in lean people, a new study shows.

Published in the September issue of Diabetes, a group of researchers from the Temple University School of Medicine analyzed fat samples from the upper thighs of six lean and six obese people.

They found significant differences in the fat cells of the obese participants compared with the lean participants.

"The fat cells we found in our obese patients were deficient in several areas," study author Guenther Boden, the Laura H. Carnell Professor of Medicine and chief of endocrinology, said in Temple press release.

Boden said that the obese people's fat cells showed stress on the endoplasmic reticulum (ER), which helps cells synthesize proteins and monitor how they are folded. When the ER is stressed, Boden explained, it produces several proteins that ultimately lead to insulin resistance. Insulin resistance, in turn, plays a major role in the development of obesity-related conditions.

The differences in the fat cells between obese and lean people may help explain the link between obesity and a higher risk of diabetes, heart disease, and stroke, Boden theorized.

More information

The National Heart, Lung, and Blood Institute has more about overweight and obesity.



-- Krisha McCoy



SOURCE: Temple University, news release, Aug. 27, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Pancreatic Cells Turned Into Insulin-Producing Beta Cells
2. UNC researcher aims to unmask cancer cells to trigger bodys immune system
3. Bone marrow stem cells may help control inflammatory bowel disease
4. By amplifying cell death signals, scientists make precancerous cells self-destruct
5. Researchers Hunt Normal Cells That Give Rise to Cancer
6. Childhood brain tumor traced to normal stem cells gone bad
7. B Cells Can Act Alone in Autoimmune Diseases
8. Key to virulence protein entry into host cells discovered
9. Methadone Kills Resistant Leukemia Cells
10. Scientists Turn Skin Cells Into Motor Neurons in ALS Patients
11. Protein made by fat cells may increase risk of heart attack in older adults
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... TX (PRWEB) , ... June 25, 2016 , ... Austin ... of the American College of Mohs Surgery and to Dr. Russell Peckham for medical ... and highly effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery ...
(Date:6/25/2016)... , ... June 25, 2016 , ... ... and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as a ... area —Johnson is one of the first doctors to perform the treatment. Orthobiologics ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... June 19, ... the dangers associated with chronic pain and the benefits of holistic treatments, Serenity ... who are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Comfort Keepers® ... American Cancer Society and the Road To Recovery® program to drive cancer patients to ... and other adults to ensure the highest quality of life and ongoing independence. ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... client, The Grove Investment Group (TGIG), has initiated cultivation and processing operations at ... Las Vegas and Pahrump, Nevada. , Puradigm is the manufacturer of a complete ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Research and Markets has announced the addition ... Chemical (Sugar, Petrochemical, Glycerin), Inorganic Chemical), Functionality (Filler, Binder, ... Forecast to 2021" report to their offering. ... excipients market is projected to reach USD 8.1 Billion ... forecast period 2016 to 2021. The ...
(Date:6/23/2016)... , June 23, 2016 Research and ... News Issue 52" report to their offering. ... influenza treatment creates a favourable commercial environment for MedImmune to ... patient base that will serve to drive considerable growth for ... would serve to cap sales considerably, but development is still ...
(Date:6/23/2016)... -- Revolutionary technology includes multi-speaker listening to ... leaders in advanced audiology and hearing aid technology, has ... the world,s first internet connected hearing aid that opens ...      (Photo: http://photos.prnewswire.com/prnh/20160622/382240 ) , ... firsts,: , TwinLink™ - the first dual ...
Breaking Medicine Technology: