Navigation Links
Fat Cell Protein Boosts Heart Attack Risk in Elderly
Date:8/8/2008

Higher adiponectin levels may indicate underlying disease, study finds

FRIDAY, Aug. 8 (HealthDay News) -- A protein produced by fat cells may play a pivotal role in increasing an older American's risk for a heart attack even if they are losing weight, a new report says.

Levels of adiponectin increase in the bloodstream when people lose weight and appear to endanger the cardiovascular health of older people, according to the new study to be published in The Journal of Clinical Endocrinology & Metabolism.

This finding, though, appears odd, because past studies have shown high adiponectin concentration is associated with lower risks of diabetes and cholesterol abnormalities.

"This study is significant because previous findings have been contradictory, and the present investigation includes the largest number of heart attacks in an elderly group to date," Dr. Jorge Kizer, an associate professor of medicine and public health at Weill Cornell Medical College in New York City, said in a news release issued by the journal's publisher. "Our findings make a persuasive case that adiponectin is in fact associated with an increase in heart disease risk in older persons."

The new study looked at a sample of 1,386 adults, aged 65 to 100, from around the country. Of these, 604 had heart disease, with those with the highest adiponectin levels being most likely to suffer a heart attack.

The researchers theorized that higher adiponectin levels may indicate underlying disease, or even have direct harmful effects especially in the elderly. Previous studies show adiponectin increases energy expenditure in the central nervous system of mice -- something that could be significantly harmful if also occurring in older adults by accelerating the loss of skeletal muscle.

The findings are consistent, though, with other recent studies tying high adiponectin to mortality in the elderly.

"This study shows that this abundant product of fat cells is a marker and perhaps even a mediator of worsened outcomes in persons aged 65 years and older," Kizer said.

More information

The National Institute of Health has more about healthy aging.



-- Kevin McKeever



SOURCE: The Endocrine Society, news release, July 30, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Protein Key to Brain Rewiring
2. Recipe for cell reprogramming adds protein
3. Key to virulence protein entry into host cells discovered
4. DIA/AAPS Co-Sponsored Conference to Examine the Immunogenicity of Therapeutic Proteins
5. Protein made by fat cells may increase risk of heart attack in older adults
6. Scientists ID Jekyll-Hyde Protein in Lou Gehrigs Disease
7. A High-Density Lipoprotein Raising Drug That Has a Lower Discontinuation Rate Than That of Extended Release Niaspan Would Earn a 20 Percent Patient Share in the Dyslipidemia Drug Market
8. Protein Gives Doctors New Tool to Detect Melanoma
9. Protein Thought to Promote Cancer Does Opposite
10. Pressured proteins: A little pressure in proteomics squeezes 4-hour step into a minute
11. Discovery of key malaria proteins could mean sticky end for parasite
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating in cancer care, and ... in the eye of the beholder, according to experts who offered insights and commentary ... of Managed Care. For the full issue, click here . , For the ...
(Date:6/26/2016)... Birmingham, Lake Orion, Clarkston, Michigan (PRWEB) , ... ... ... their direction with respect to fertility once they have been diagnosed with endometriosis. ... for tolerable intercourse but they also require a comprehensive approach that can help ...
(Date:6/25/2016)... , ... June 25, 2016 , ... First Choice ... States, named Dr. Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm ... Medical Director of our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical ...
(Date:6/24/2016)... Los Angeles, CA (PRWEB) , ... June 24, 2016 , ... ... plastic surgery procedures that most people are unfamiliar with. The article goes on to ... known procedures, but also many of these less common operations such as calf and ...
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, P.A. ... The attorneys chosen by their peers for this recognition are considered among the top ... Shareholders received special honors as members of this year’s Legal Elite Hall of Fame: ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... June 23, 2016 Capricor ... ), a biotechnology company focused on the discovery, ... that patient enrollment in its ongoing randomized HOPE-Duchenne ... exceeded 50% of its 24-patient target. Capricor expects ... third quarter of 2016, and to report top ...
(Date:6/23/2016)... -- , , , WHEN: , ... , , , LOCATION: , , , Online, with free ... EXPERT PANELISTS:  , , , Frost & Sullivan,s Global Vice President ... Industry Analyst, Divyaa Ravishankar and Unmesh Lal, Program Manager , ... is witnessing an exceptional era. Several new demand spaces, such as ...
(Date:6/23/2016)... June 23, 2016 Revolutionary technology ... Oticon , industry leaders in advanced audiology and ... Oticon Opn ™, the world,s first internet connected ... for IoT devices.      (Photo: http://photos.prnewswire.com/prnh/20160622/382240 ... a number of ,world firsts,: , TwinLink™ ...
Breaking Medicine Technology: