Navigation Links
Fat-Burning Chemical Points to New Weight-Loss Drug

Results of lab tests with mice suggest promising new direction for research, scientists say

TUESDAY, Feb. 2 (HealthDay News) -- American scientists say they may have found a new way to trick the body into burning more fat.

Mice that were given a chemical that blocks the function of an enzyme called Fyn kinase burned more fatty acids and expended more energy, which made them leaner. This and other metabolic improvements, including increased insulin sensitivity, were because of higher levels of the "master energy switch" AMPK in the rodents' fat and muscle tissue.

The findings suggest that Fyn kinase may offer a target for a new kind of weight-loss drug, said the researchers at the Albert Einstein College of Medicine and Neuroscience. The study appears in the Feb. 3 issue of the journal Cell Metabolism.

"When there is an imbalance between what we eat and what we burn," the result is obesity, team leader Claire Bastie said in a news release from the journal. "And the problem of obesity is not going away. This is a new mechanism to help the body burn extra energy."

The experimental drug used to block Fyn kinase in the mice isn't an ideal candidate for clinical trials in humans because both Fyn kinase and AMPK have effects in the brain as well as in fat and muscle.

"Our next goal is to design [a drug] extremely specific to muscle and [fat]," Bastie said.

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases has more about weight loss.

-- Robert Preidt

SOURCE: Cell Press, news release, Feb 2, 2010

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Pacific Shore Holdings, Inc. Launches Burner Balm a Revolutionary, Energy-Boosting, Appetite-Suppressing, Fat-Burning Lip Balm - Natural, Green and Cost-Effective - Featured on NBCs Today Show
2. Impaired fat-burning gene worsens diabetes
3. Mount Sinai finds prenatal exposure to certain chemicals affects childhood neurodevelopment
4. Biochemical profile may help diagnose, determine aggressiveness of prostate cancer
5. Flame-Retardant Chemical Linked to Conception Problems
6. Poop dermatitis linked to fashionable toilet seats, harsh chemicals
7. Stain repellent chemical linked to thyroid disease in adults
8. FDAs BPA Announcement an About Face on the Toxic Chemical
9. Chemical BPA Linked to Heart Disease Risk
10. Breast Growth in Boys Might Be Linked to Plastics Chemical
11. When Will FDA Speak Out on Toxic Plastics Chemical BPA?
Post Your Comments:
(Date:6/27/2016)... ... June 27, 2016 , ... recently awarded their highest five-star rating to ... of individuals in the United States and Canada wear eyeglasses. Once considered to be ... vision and make a fashion statement. Even celebrities use glasses as a way of ...
(Date:6/26/2016)... ... June 26, 2016 , ... Brent Kasmer, a legally blind and certified personal trainer is helping ... fitness app. The fitness app plans to fix the two major problems leading the fitness ... size fits all type program , They don’t eliminate all the reasons people ...
(Date:6/25/2016)... , ... June 25, 2016 , ... "With 30 hand-drawn ... specific project," said Christina Austin - CEO of Pixel Film Studios. , ProHand ... all within Final Cut Pro X . Simply select a ProHand generator and ...
(Date:6/25/2016)... Canada (PRWEB) , ... June 25, 2016 , ... Conventional ... pursuit of success. In terms of the latter, setting the bar too high can ... risk more than just slow progress toward their goal. , Research from ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Pulmonary ... Dallas that it will receive two significant new grants to support its work ... marked its 25th anniversary by recognizing patients, medical professionals and scientists for their ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... June 24, 2016  Consumers have taken a ... have placed more emphasis on patient outcomes. ... programs in the pharmaceutical industry have evolved beyond ... pharmaceutical companies are focusing on becoming more patient-oriented ... products and services that improve health. ...
(Date:6/24/2016)... , June 24, 2016 ... of the "Structural Electronics 2015-2025: Applications, Technologies, ... In-Mold Electronics, Smart Skin, ... Photovoltaics Structural electronics involves electronic ... load-bearing, protective structures, replacing dumb structures such as ...
(Date:6/24/2016)... India , June 24, 2016 ... Needles Market by Type (Standard Pen Needles, Safety Pen ... Therapy (Insulin, GLP-1, Growth Hormone), Mode of Purchase (Retail, ... by MarketsandMarkets, This report studies the market for the ... expected to reach USD 2.81 Billion by 2021 from ...
Breaking Medicine Technology: