Navigation Links
Fat-Burning Chemical Points to New Weight-Loss Drug
Date:2/2/2010

Results of lab tests with mice suggest promising new direction for research, scientists say

TUESDAY, Feb. 2 (HealthDay News) -- American scientists say they may have found a new way to trick the body into burning more fat.

Mice that were given a chemical that blocks the function of an enzyme called Fyn kinase burned more fatty acids and expended more energy, which made them leaner. This and other metabolic improvements, including increased insulin sensitivity, were because of higher levels of the "master energy switch" AMPK in the rodents' fat and muscle tissue.

The findings suggest that Fyn kinase may offer a target for a new kind of weight-loss drug, said the researchers at the Albert Einstein College of Medicine and Neuroscience. The study appears in the Feb. 3 issue of the journal Cell Metabolism.

"When there is an imbalance between what we eat and what we burn," the result is obesity, team leader Claire Bastie said in a news release from the journal. "And the problem of obesity is not going away. This is a new mechanism to help the body burn extra energy."

The experimental drug used to block Fyn kinase in the mice isn't an ideal candidate for clinical trials in humans because both Fyn kinase and AMPK have effects in the brain as well as in fat and muscle.

"Our next goal is to design [a drug] extremely specific to muscle and [fat]," Bastie said.

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases has more about weight loss.



-- Robert Preidt



SOURCE: Cell Press, news release, Feb 2, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Pacific Shore Holdings, Inc. Launches Burner Balm a Revolutionary, Energy-Boosting, Appetite-Suppressing, Fat-Burning Lip Balm - Natural, Green and Cost-Effective - Featured on NBCs Today Show
2. Impaired fat-burning gene worsens diabetes
3. Mount Sinai finds prenatal exposure to certain chemicals affects childhood neurodevelopment
4. Biochemical profile may help diagnose, determine aggressiveness of prostate cancer
5. Flame-Retardant Chemical Linked to Conception Problems
6. Poop dermatitis linked to fashionable toilet seats, harsh chemicals
7. Stain repellent chemical linked to thyroid disease in adults
8. FDAs BPA Announcement an About Face on the Toxic Chemical
9. Chemical BPA Linked to Heart Disease Risk
10. Breast Growth in Boys Might Be Linked to Plastics Chemical
11. When Will FDA Speak Out on Toxic Plastics Chemical BPA?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/30/2016)... ... April 30, 2016 , ... Orlando-based Maximized Living has ... go for gold in Rio. Under the care of Maximized Living doctors at ... In an unprecedented showing, Maximized Living is sending the largest contingent of elite chiropractors ...
(Date:4/29/2016)... ... April 30, 2016 , ... Mercy College is expanding ... The following programs will be expanding due to high demand: Master of Business Administration ... will begin this summer. , School of Business Graduate Program Chair Dr. ...
(Date:4/29/2016)... (PRWEB) , ... April 29, 2016 , ... ... Two Ten Footwear Foundation, the national charitable foundation serving the footwear industry, has ... 8,000 volunteers representing more than 130 companies across 23 states during the months ...
(Date:4/29/2016)... ... April 29, 2016 , ... ... announces the addition Onnit brand Alpha BRAIN and New Mood Daily-Stress Formula for ... and mood optimization products to the store is just one more way Shamangelic ...
(Date:4/29/2016)... ... April 29, 2016 , ... On Tuesday, April 26, 2016 members ... celebrated the signature of Gov. Nathan Deal on SB 258, the “Rural Health Care ... Cumming), offers a 70% tax credit to individuals and corporations which donate directly to ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... , April 28, 2016 ... George Phillips und Stephen ...    ArisGlobal®, ein führender Anbieter ... gab heute bekannt, dass neue Führungskräfte zum ... gestoßen sind, die vielfältige Erfahrungen mitbringen.  Dies ...
(Date:4/28/2016)... -- Treato , the single largest ... that it has been named a Cool Vendor by ... Sciences, 2016, Stephen Davies , Michael ... life-science- oriented analytics, algorithms and smart machine technology in ... medication ingestion, and analyze unstructured information.   ...
(Date:4/28/2016)... , April 28, 2016 Dr. ... and Ste phen ... ArisGlobal®, a leading provider of cloud-based software solutions for life ... Pharmacovigilance team to bring a wealth of insight to a growing ... pharmacovigilance knowledge. George Phillips joined ArisGlobal in ...
Breaking Medicine Technology: