Navigation Links
Fast new method for mapping blood vessels may aid cancer research
Date:10/31/2011

WASHINGTON, Oct. 31Like normal tissue, tumors thrive on nutrients carried to them by the blood stream. The rapid growth of new blood vessels is a hallmark of cancer, and studies have shown that preventing blood vessel growth can keep tumors from growing, too. To better understand the relationship between cancer and the vascular system, researchers would like to make detailed maps of the complete network of blood vessels in organs. Unfortunately, the current mapping process is time-consuming: using conventional methods, mapping a one-centimeter block of tissue can take months. In a paper published in the October issue of the Optical Society's (OSA) open-access journal Biomedical Optics Express, computational neuroscientists at Texas A&M University, along with collaborators at the University of Illinois and Kettering University, describe a new system, tested in mouse brain samples, that substantially reduces that time.

The method uses a technique called knife-edge scanning microscopy (KESM). First, blood vessels are filled with ink, and the whole brain sample is embedded in plastic. Next, the plastic block is placed onto an automated vertically moving stage. A diamond knife shaves a very thin slice one micrometer or less off the top of the block, imaging the sample line by line at the tip of the knife. Each tiny movement of the stage triggers the camera to take a picture. In this way, the researchers can get the full 3-D structure of the mouse brain's vascular network from arteries and veins down to the smallest capillaries in less than two days at full production speed. In the future the team plans to augment the process with fluorescence imaging, which will allow researchers to link brain structure to function.


'/>"/>

Contact: Angela Stark
astark@osa.org
202-416-1443
Optical Society of America
Source:Eurekalert  

Page: 1

Related medicine news :

1. Less invasive anesthetic methods better for endovascular aneurysm repair
2. Researchers develop method to better estimate vaccine coverage
3. Improved method for detecting mutant DNAs
4. New method to diagnose sinusitis could reduce use of antibiotics
5. Scripps research scientist wins $3.6 million NIH Method to Extend Research in Time award to study alcoholism in Native Americans
6. Long-term effectiveness of new family planning method shown in study
7. Firearm Suicide Methods Vary by Gender: Study
8. Stanford researchers invent sutureless method for joining blood vessels
9. Method to Detect When Patients Wake During Surgery Fails to Impress
10. Study: Inexpensive method detects ALK rearrangement in lung cancer patients
11. Researchers discover method to decrease harmful cyanogens and increase protein levels in key crop
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Fast new method for mapping blood vessels may aid cancer research
(Date:12/8/2016)... ... December 08, 2016 , ... Coffey Agencies, a ... and commercial clients in the northern Alabama and Georgia regions, is embarking on ... 1977, Nobis Works has built a network of support and education facilities to ...
(Date:12/7/2016)... , ... December 07, 2016 , ... DrugDev ... announcement that it is one of the early adopters completing EU-U.S. Privacy Shield Certification ... designed to provide companies on both sides of the Atlantic with a mechanism to ...
(Date:12/7/2016)... (PRWEB) , ... December 07, 2016 , ... ... celebrating the passage of the most comprehensive mental health systems reform legislation in ... support of the President, and the commitment of our elected officials to improving ...
(Date:12/7/2016)... York, NY (PRWEB) , ... December 07, 2016 ... ... amounts of the drug in their bodies, a researcher at the Icahn School ... journal Pediatric Research. , The study found that when young children are exposed ...
(Date:12/7/2016)... ... December 07, 2016 , ... ... of Smart Device Remote Control through a new partnership with Splashtop Inc. This ... strengthens its mobile solutions to help businesses maximize their uptime and productivity. , ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... , Dec. 8, 2016 Henry Schein, Inc. (Nasdaq: ... care products and services to office-based dental, animal health and ... equity investment in Marrodent, one of Poland,s ... $32 million. This transaction was announced on August 30, 2016. ... Poland since 2014, and Marrodent marks ...
(Date:12/8/2016)... Dec 8, 2016 Research and Markets has announced ... report to their offering. ... , The report provides separate comprehensive ... , and Rest of World. Annual estimates and ... historic analysis is provided for these markets. Market data and analytics are ...
(Date:12/7/2016)... Dec. 7, 2016 "Lantus (Insulin Glargine) Biosimilar Clinical Trial & ... biosimilar version of Lantus drug in clinical pipeline. Currently 5 biosimilar version ... Japan , Kenya , Czech ... , China , Slovakia , ... 2 diabetes mellitus. The patent on Lantus expired in 2014. Lantus ...
Breaking Medicine Technology: