Navigation Links
Fast new method for mapping blood vessels may aid cancer research
Date:10/31/2011

WASHINGTON, Oct. 31Like normal tissue, tumors thrive on nutrients carried to them by the blood stream. The rapid growth of new blood vessels is a hallmark of cancer, and studies have shown that preventing blood vessel growth can keep tumors from growing, too. To better understand the relationship between cancer and the vascular system, researchers would like to make detailed maps of the complete network of blood vessels in organs. Unfortunately, the current mapping process is time-consuming: using conventional methods, mapping a one-centimeter block of tissue can take months. In a paper published in the October issue of the Optical Society's (OSA) open-access journal Biomedical Optics Express, computational neuroscientists at Texas A&M University, along with collaborators at the University of Illinois and Kettering University, describe a new system, tested in mouse brain samples, that substantially reduces that time.

The method uses a technique called knife-edge scanning microscopy (KESM). First, blood vessels are filled with ink, and the whole brain sample is embedded in plastic. Next, the plastic block is placed onto an automated vertically moving stage. A diamond knife shaves a very thin slice one micrometer or less off the top of the block, imaging the sample line by line at the tip of the knife. Each tiny movement of the stage triggers the camera to take a picture. In this way, the researchers can get the full 3-D structure of the mouse brain's vascular network from arteries and veins down to the smallest capillaries in less than two days at full production speed. In the future the team plans to augment the process with fluorescence imaging, which will allow researchers to link brain structure to function.


'/>"/>

Contact: Angela Stark
astark@osa.org
202-416-1443
Optical Society of America
Source:Eurekalert  

Page: 1

Related medicine news :

1. Less invasive anesthetic methods better for endovascular aneurysm repair
2. Researchers develop method to better estimate vaccine coverage
3. Improved method for detecting mutant DNAs
4. New method to diagnose sinusitis could reduce use of antibiotics
5. Scripps research scientist wins $3.6 million NIH Method to Extend Research in Time award to study alcoholism in Native Americans
6. Long-term effectiveness of new family planning method shown in study
7. Firearm Suicide Methods Vary by Gender: Study
8. Stanford researchers invent sutureless method for joining blood vessels
9. Method to Detect When Patients Wake During Surgery Fails to Impress
10. Study: Inexpensive method detects ALK rearrangement in lung cancer patients
11. Researchers discover method to decrease harmful cyanogens and increase protein levels in key crop
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Fast new method for mapping blood vessels may aid cancer research
(Date:3/29/2017)... ... March 29, 2017 , ... Patients interested in receiving ... from Dr. Jamie Cameron, with or without a referral. The FASTBRACES system is ... Depending on each patient’s case, treatment with the FASTBRACES system could be completed ...
(Date:3/29/2017)... ... March 29, 2017 , ... ... (GRMA) is growing as it continues developing an ANSI-approved, consensus-based American National ... organization, which plans to publish the first ANSI-approved GMP standard for dietary ...
(Date:3/29/2017)... ... March 29, 2017 , ... ... for documenting and diagramming network and data center assets and audio-video devices has ... can request new equipment shapes for free and download shapes and stencils from ...
(Date:3/29/2017)... ... March 29, 2017 , ... An ... braces. "The rubber bands used in conjunction with my braces always rubbed against ... design a way to prevent this problem." The O.B.S. was the result of ...
(Date:3/29/2017)... , ... March 29, 2017 , ... ... many scientific laboratories. The assembly protocols involve many repetitive steps and often scientists ... automation, which enables the high-throughput needed, and results in a lower error rate ...
Breaking Medicine News(10 mins):
(Date:3/29/2017)... -- The leader in accelerated orthodontics, OrthoAccel ® Technologies, ... Manal Ibrahim , Kenji Ojima , ... featured microlecture presenters at the AcceleDent ® booth ... Annual Session, April 21-25, 2017. Orthodontists and their staff ... 11:20 a.m. On the opening morning of AAO exhibitions, ...
(Date:3/29/2017)... , March 29, 2017  Maxor National Pharmacy Services, ... that it has named Leah Bailey as ... divisions of the company. With more than ... previous 8 years focused on health care, Bailey joins ... tenure at Prime, Bailey advised the PBM, Specialty, and ...
(Date:3/29/2017)... JOSE, Calif. , March 29, 2017  Designers ... now significantly reduce solution size by 50% and extend ... Q ) power management integrated circuit (PMIC) from Maxim ... wearable PMIC supports a low input voltage of just ... Zinc Air and Silver Oxide, as well as the ...
Breaking Medicine Technology: