Navigation Links
Farm moms may help children beat allergies
Date:5/20/2008

ATS 2008, TORONTOMothers exposed to farms, particularly to barns and farm milk, while pregnant confer protection from allergies on their newborns, according to a group of German researchers, who will present their findings at the American Thoracic Societys 2008 International Conference in Toronto on Wednesday, May 21.

In a study of the children of 18 farming mothers and 59 non-farming mothers, the researchers believe they have proved their hypothesis that a mothers farm exposure affects her babys T regulatory cells. These cells, it is now believed, act to suppress immune responses and thereby maintain immune system homeostasis to contribute to healthy immune development.

We found that the babies of mothers exposed to farms have more and better functioning regulatory T cells, explained Bianca Schaub, M.D., who led the research team at University Childrens Hospital in Munich. The effect was strongest among those mothers who entered barns or drank farm milk.

Dr. Schaub and her researchers believe that the findings represent a potential immunological explanation of the mechanism that produces the protective farm effect on the development of childhood atopic diseases.

To conduct this study, the investigators assessed exposure through detailed questionnaires. They then recorded the number of regulatory T cells (CD4+CD25+ high, Foxp3+) and their associated genes (Foxp3/LAG3) after stimulating cord blood mononuclear cells with microbial stimuli and allergens. Expression of the regulatory T cells and associated genes were significantly higher in the blood drawn from the umbilical cord of babies whose moms spent time on a farm.

According to Dr. Schaub, the findings support the paradigm shift from attributing allergic diseases solely to an impaired balance between anti-allergic Th1 cells and pro-allergic Th2 cells. It may be possible that T regulatory cells are capable of preventing an allergic response at an early time point by suppressing Th2 cells.

It is a long way off, she concluded, but these findings may one day hopefully help researchers to develop an effective preventive strategy, perhaps even a vaccine, against allergic diseases.


'/>"/>

Contact: Keely Savoie
ksavoie@thoracic.org
212-315-8620
American Thoracic Society
Source:Eurekalert

Related medicine news :

1. Children of depressed moms do better when dad is involved, SLU researcher finds
2. High pollution linked to poor lung function growth in children in Mexico City
3. NYC-area 1st: Morgan Stanley Childrens Hospital performs transcatheter pulmonary valve replacement
4. Obese Children Miss More School Days
5. Ultra-Runner to Run 63 Marathons in 63 Days for Children with Incurable Disease
6. Psoriasis Cure Now offers Back to School Resources for Parents of Children with Psoriasis
7. Researchers estimate about 9 percent of US children age 8 to 15 meet criteria for having ADHD
8. Majority of 2.4 Million U.S. Children With ADHD Not Diagnosed or Consistently Treated, According to New Gold Standard Study by Cincinnati Childrens Researchers
9. Practice-based intervention has sustained benefits for children and families
10. 1.5 million children could be saved
11. Annual flu shot cuts need for doctors visits, hospitalization among children
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/12/2016)... ... February 12, 2016 , ... Fixed Dose ... – 3:00 p.m. EST, http://www.fdanews.com/fixeddosecombination , Fixed dose ... products, garnering increased attention from all stakeholders in the development of new chemical ...
(Date:2/12/2016)... ... February 12, 2016 , ... The ThedaCare Center for Healthcare ... Hospital on April 5-7. The series is a multi-day, multi-workshop event designed to ... cover a broad range of topics, including coaching skills, the scientific method of ...
(Date:2/12/2016)... ... 12, 2016 , ... The Jones Agency, a family owned insurance company with ... a cooperative charity drive with the Tarrant Area Food Bank in the hopes of ... families in need, the Tarrant County Food Bank offers hope and security to the ...
(Date:2/12/2016)... ... 2016 , ... Miami Dental Specialists is excited to bring patients the choice ... in January, Miami Dental Specialists will offer the non-metal implants as a safe, holistic ... be chosen by the dental implant manufacturer, Straumann, to bring this cutting-edge technology to ...
(Date:2/12/2016)... ... February 12, 2016 , ... Atlantic Information Services, ... Plans and PBMs,” an upcoming Feb. 24 webinar that will discuss ways health ... therapeutic categories, such as the $1,000-per-pill hepatitis C treatment Sovaldi and high-cost PCSK9 ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... FRAMINGHAM, Mass. , Feb. 12, 2016   ... scheduled a conference call and webcast to discuss its ... December 31, 2015, on Thursday, February 25, 2016 at ... financial results prior to the conference call and webcast.  ... the company,s financial results, highlights from the fourth quarter ...
(Date:2/12/2016)... 2016 On Thursday, Feb. 11, 2016, surgeons ... David,s North Austin Medical Center successfully completed the first ... ® Surgical System with Trumpf Medical,s advanced operating ... Lakshman , M.D., colorectal surgeon at the Texas Institute ... Table Motion technology, which seamlessly combines the da Vinci ...
(Date:2/12/2016)... , 12 februari 2016 ... een toonaangevende leverancier van productie en ontwikkeling ... industrieën, kondigt vandaag een uitbreiding aan van ... haar locatie in Charleston, SC ... geleid tot meerdere recente investeringen. ...
Breaking Medicine Technology: