Navigation Links
Family history of colorectal cancer linked with reduced risk of cancer recurrence
Date:6/3/2008

ning just the risk for cancer recurrence, patients with a family history of colorectal cancer had a 26 percent reduced risk compared with patients without a family history. Cancer recurrence occurred in 27 percent of patients with a family history of colorectal cancer and 35 percent of patients without a family history. The reduced risk of death for patients with a family history of colorectal cancer was 25 percent.

The apparent benefit associated with family history was stronger with an increasing number of affected family members. Compared with participants without a family history of colorectal cancer, participants with two or more affected relatives had a 51 percent lower risk for cancer recurrence or death.

Beyond rare, well-characterized hereditary colorectal cancer syndromes, our data support the hypothesis that a relatively common though less penetrant genetic predisposition may not only influence colorectal cancer risk but also patient survival. This finding may reflect a distinct underlying molecular and pathogenic mechanism in cancers that develop in the setting of a common (i.e., sporadic) family history, the researchers write. Further studies are needed to more fully elucidate potential mechanisms by which a common family history may influence the outcome for patients with colorectal cancer.

(JAMA. 2008;299[21]:2515-2523. Available pre-embargo to the media at www.jamamedia.org)

Editors Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.


Editorial: Familial Colorectal Cancer - A Genetics Treasure Trove for Medical Discovery

In an accompanying editorial, Boris Pasche, M.D., Ph.D., of the Northwestern University Feinberg School of Medicine, Chicago, and Contributing Editor, JAMA, comments on the results of the study by Chan and col
'/>"/>

Contact: Robbin Ray
617-632-4090
JAMA and Archives Journals
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Work-Family Conflict Dogs Air Force Women After Deployment
2. Work-Family Conflict Dogs Air Force Women After Deployment
3. Isolation of a new gene family essential for early development
4. Lake Elsinore Family Caregiver Receives Free Power Wheelchair From The SCOOTER Store
5. Family-based treatment more effective than supportive psychotherapy in treating bulimia
6. R. P. Simmons Family Foundation Pledges $2 Million for New Childrens Hospital of Pittsburgh of UPMC Campus
7. BlueCare(R) Family Plan, a HUSKY Health Plan from Anthem Blue Cross and Blue Shield in Connecticut, Raises Awareness, Funds and Diapers for New Haven Diaper Bank
8. Regional Center of Orange County Expands Family Support Resources to Meet Growing Needs
9. The Arthur M. Blank Family Foundation Pushes for Pre-K Expansion in Georgia
10. Family History Has Strong Effect on Cardiac Risk
11. Childs Flu Shot Helps Whole Family
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/9/2014)... policing injection drug users in Russia might contribute ... A study, conducted by researchers from Boston University ... with St. Petersburg Pavlov State University, sought to ... health outcomes of a cohort of HIV-positive people ... who were arrested by police were more likely ...
(Date:7/9/2014)... in French . ... old teens, including brain structure and function, personality, life experiences ... go on to develop binge drinking within the next two ... variables such as life events and a family history of ... Whether or not the child had had a single drink ...
(Date:7/9/2014)... world have been linked to an emerging fungal ... National Institute for Mathematical and Biological Synthesis (NIMBioS) ... , In a series of mathematical models, ... of internal organs in frogs, could cause extinction ... are exposed to the virus every few years, ...
(Date:7/9/2014)... Infectious Diseases (NIAID), part of the National Institutes ... of CRS3123, an investigational oral antibiotic intended to ... ) infection. CRS3123 (previously known as REP3123) is ... while sparing normal intestinal bacteria. , The Phase ... men and women ages 18 to 45 in ...
(Date:7/9/2014)... labels handed out by pharmacists may be misread ... according to new research by the University of ... Blind)., The study, published recently in the ... prescription medications dispensed by pharmacies do not consistently ... simply following recommended guidelines for font size, use ...
Breaking Medicine News(10 mins):Health News:BU researchers relate arrests with HIV risk environment 2Health News:What drives a child to abuse alcohol? 2Health News:Study predicts ranavirus as potential new culprit in amphibian extinctions 2Health News:NIH launches Phase I clinical trial of novel drug to treat Clostridium difficile infection 2Health News:Most prescription labels fail to meet guidelines, risking dosage errors 2
... ... free NeedyMeds iPhone app . , ... (Vocus) August 21, 2009 -- NeedyMeds, the premier source of information on programs that help ... its drug discount card. Simply by showing the pharmacist an image on their iPhones, people can ...
... , , , LOS ... Inc., announced the launch of Energy-X, a new lip balm that delivers ... or artificial sweeteners. With zero calories, Energy-X provides the energy boost consumers ... , "Energy-X is applied directly on the lips and ...
... all know that influenza vaccination helps prevent disease, but ... prevent another public health problem: inappropriate antibiotic use. The ... 1, 2009 issue of Clinical Infectious Disease , ... the Canadian province of Ontario introduced a universal immunization ...
... Increase is small but worth noting, expert says, as ... -- Smokeless tobacco increases the risk of fatal heart ... of 11 studies conducted in North America and Sweden. ... of smokeless tobacco products has increased in Europe and ...
... to list the negative stereotypes attributed to the elderly: ... What,s unsettling is that those stereotypes can be ... Research conducted by the University of Alberta,s Sheree ... stereotypes exist in some children at that age, which ...
... , WASHINGTON, Aug. 20 Congressman Chaka ... national "March for Healthcare" in Washington on September 13 to mobilize ... announced today. , , The Philadelphia Congressman, ... on colleagues in Congress to endorse the proposal for a march, ...
Cached Medicine News:Health News:iPhone App That Saves Money on Prescription Medicines 2Health News:Energy-X Lip Balm Delivers Wake-Up Call to Consumers 2Health News:Visits to Nana's may keep toddlers from developing negative age stereotypes 2
(Date:1/15/2014)... , Jan. 15, 2014  Humberto C. Antunes,  Galderma  ... Award" from the Journal of Drugs in Dermatology ... Clinical Conference (ODAC). The event is January 17-20, 2014, at the ... . The ODAC is a ...
(Date:1/15/2014)... PALM BEACH GARDENS, Fla. , Jan. 15, 2014  In an ... C. difficile and TB in ambulances and other transport vehicles, an ... being used by rescue personnel for the first time. ... coming in contact with these deadly pathogens, West Palm ...
(Date:1/15/2014)... PHILADELPHIA , Jan. 15, 2014  Echo Therapeutics, Inc. ... company developing its Symphony® CGM System as a non-invasive, ... Robert F. Doman , Executive Chairman and Interim CEO ... Capital Markets, Tenth Annual Equity Conference. ...
Breaking Medicine Technology:Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 2Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 3Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 4Superbugs No Longer Ride In Rescue Vehicles 2Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 2Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 3
... HIV Vaccine--PHILADELPHIA, May 17 A research team may ... invention of an effective HIV vaccine, by using an ... developers. By using gene transfer technology that produces molecules ... by a virus closely related to HIV -- the ...
... Findings Confirm Glycerin Accelerates the Healing Process , ... Today , a leading expert ... from a study demonstrating that glycerin helps to speed ... resulting in less bruising and skin discoloration.In a double-blinded, ...
Cached Medicine Technology:Novel Vaccine Approach Offers Hope in Fight Against HIV 2Novel Vaccine Approach Offers Hope in Fight Against HIV 3Glycerin Proven to Improve Bruising and Swelling Caused By Trauma to Skin 2
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: