Navigation Links
Family history of alcoholism affects response to drug used to treat heavy drinking
Date:9/19/2007

Philadelphia, PA, September 19, 2007 Naltrexone is one of four oral medications approved by the U.S. Food and Drug Administration (FDA) for the treatment of alcoholism. A recent large multicenter research study of alcohol dependence supported by the National Institute of Alcoholism and Alcohol Abuse (NIAAA), the COMBINE Study, suggested that naltrexone produced a modest but significant benefit but another FDA-approved medication, acamprosate, was ineffective. Perhaps consistent with its modest effects in COMBINE, naltrexone is not widely prescribed in the treatment of alcoholism. Yet, clinicians report that naltrexone may have significant benefits for individual patients. To make naltrexone a more useful medication, it would be important to begin to identify groups of patients who might be more or less likely to show a significant clinical benefit from naltrexone prescription and to understand the causes of differential naltrexone efficacy. A new study that will appear in the September 15th issue of Biological Psychiatry suggests that alcohol dependent individuals with a family history of alcohol dependence may be more likely than alcohol dependent individuals without a family history of alcohol dependence to reduce their drinking in the laboratory when prescribed naltrexone.

Krishnan-Sarin and colleagues at the NIAAA Center for the Translational Neuroscience of Alcoholism studied alcohol consumption in the laboratory by alcohol-dependent individuals who were not seeking treatment. The participants were studied in the laboratory after 6 days of treatment with 0 mg (placebo), 50 mg, or 100 mg of naltrexone. The authors discovered that naltrexone decreased drinking in those with a family history of alcoholism and this effect was greatest with the highest naltrexone dose. However, it increased drinking in those without a family history of alcoholism and this effect was greatest at the highest naltrexone dose.

John H. Krystal, M.D., one of
'/>"/>

Contact: Jayne Dawkins
ja.dawkins@elsevier.com
215-239-3674
Elsevier
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Family planning with folate
2. Breast cancer in younger women strongly linked to family history
3. Accuracy of Some Natural Family Planning Methods Questioned .
4. Alcoholism Influenced By Both Genetics & Family Environment
5. Restless leg syndrome can be a family trait
6. Merck to pay $ 253.5 million to Vioxx victim family
7. Family Counseling To Encourage Children Eat Healthy
8. Survey finds that discussion with family very crucial in organ donation decision
9. Effective family control measures and stem cell research focus of Indian Government
10. Family history of alcoholism influences reaction to advice
11. Family planning is insisted upon Muslims by Shia cleric
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... Beverly Hills, CA (PRWEB) September 16, 2014 ... to announce the launch of ACLsurgeryLA.com , a ... various ACL injuries. As an avid sports lover ... best options for treatment and recovery from injuries to ... this opportunity to offer patients a resource dedicated specifically ...
(Date:9/16/2014)... NY (PRWEB) September 16, 2014 Registration ... Run For The Warriors®, a 10K, 5K, and 1-mile ... The race is sponsored by Local 338 RWDSU/UFCW, the ... will begin at the Town of Babylon Town Hall ... http://www.hopeforthewarriors.org/2014LIRun . The run is organized by Hope ...
(Date:9/16/2014)... Alabama (PRWEB) September 16, 2014 *To find ... AL, visit Achieve Clinical Research on the web ( http://www.achieveclinical.com/trial/pneumonia-vaccine/ ... those who qualify:, There is no ... , Compensation may be provided for time ... pneumonia and influenza are the eighth leading cause of death ...
(Date:9/16/2014)... *Anyone who is interested in learning more about ... visit Avail Clinical Research on the web ( http://www.availclinical.com/trial/common-cold/ ... Why Are Volunteers Needed? , The common cold is ... While infections may not be as deadly as in ... visits to the doctor than any other medical condition ...
(Date:9/16/2014)... DC (PRWEB) September 16, 2014 ... civic information media site, launches their new site ... has additional features aimed at making information easier ... we sift, we distill into one-page, easy-to-read pages ... American should know!” says Virginia Downie, retired college ...
Breaking Medicine News(10 mins):Health News:Los Angeles Orthopedic Surgeon Spotlights ACL Conditions With New Website 2Health News:Los Angeles Orthopedic Surgeon Spotlights ACL Conditions With New Website 3Health News:The Hope For The Warriors Long Island Run For The Warriors to Honor Wounded and Families of the Fallen 2Health News:The Team at Achieve Clinical Research is Enrolling Qualified Individuals to Participate in a Pneumonia Vaccine Clinical Trial in Birmingham, Alabama 2Health News:The Team at Achieve Clinical Research is Enrolling Qualified Individuals to Participate in a Pneumonia Vaccine Clinical Trial in Birmingham, Alabama 3Health News:Avail Clinical Research Is Looking for Healthy Adults Who Are Interested in Participating in a Common Cold Clinical Trial near Orlando, Florida 2Health News:Avail Clinical Research Is Looking for Healthy Adults Who Are Interested in Participating in a Common Cold Clinical Trial near Orlando, Florida 3Health News:JustThoughtYouShouldKnow.org Debuts New Website 2
... More than $1.1 billion a year is spent on ... study reports the state has a rising number of people ... hunger. The MU Interdisciplinary Center for Food Security has released ... Missouri Hunger Atlas details the distribution of hunger in the ...
... found remission occurred faster, more often with immunosuppressive ... News) -- Treating Crohn,s disease more aggressively resulted ... of researchers reports. , Using more than one ... with the disease was more effective in inducing ...
... 22 The Cleveland Department of,Health and Cincinnati ... to fund community lead poisoning prevention projects.,U.S. Environmental ... of a,national goal to eliminate childhood lead poisoning ... The Cleveland Department of Health received $99,990 to ...
... NexGen Biofuels Ltd.,(NASDAQ: NXGN ) (the "Company") ... The company has changed its name on January 28, ... more clearly reflect its new business, which,is to pursue ... through the acquisition of existing production facilities and/or,through the ...
... Health is creating a,network of more than 3,000 ... providing patients with more convenient access to,consistently high-quality ... a presence in dozens of cities and towns ... Central Valley and from Santa Cruz,to the Mother ...
... YORK, Feb. 22 The Physicians Coalition,for Injectable ... on,the safety of Botox(R) injections after reports of ... "Consumers who have had Botox(R) injections for ... indications should not be alarmed,by recent reports of ...
Cached Medicine News:Health News:MU research team releases first Missouri Hunger Atlas 2Health News:Aggressive Therapy for Crohn's Disease Produces Better Outcomes 2Health News:Aggressive Therapy for Crohn's Disease Produces Better Outcomes 3Health News:Sutter Health Launches Northern California Physician Network 2Health News:Sutter Health Launches Northern California Physician Network 3Health News:Clarity for Consumers on Botox Complication and Death Reports 2Health News:Clarity for Consumers on Botox Complication and Death Reports 3Health News:Clarity for Consumers on Botox Complication and Death Reports 4
(Date:9/15/2014)... 2014  Decision Resources Group,s new Manhattan ... that online information and other value-added services ... their offering and support physicians. Physicians who ... rely on websites, mobile apps and other ... physicians are looking to manufacturers to provide ...
(Date:9/15/2014)... MINNEAPOLIS , Sept. 15, 2014 ... a non-profit professional association serving more than 4,500 ... released its 2015 SCALENDAR, which chronicles corporate fines ... compliance and ethics professionals have a ready reference ... "We developed the SCALENDAR to help ...
(Date:9/15/2014)... , Sept. 15, 2014 Research and ... Worldwide Market for In Vitro Diagnostic Tests, 9th Edition" ... covers the entirety of the clinical testing market and all ... Used by Top IVD Companies For Business Planning. ... based on the market events of 2013 and early 2014. ...
Breaking Medicine Technology:Physician device decision-makers show strong demand for device manufacturer digital content and support 2Physician device decision-makers show strong demand for device manufacturer digital content and support 3More than $55 billion in fines and settlements added by SCCE to its 2015 Corporate Scandal Calendar 2The Worldwide Market for In Vitro Diagnostic Tests, 9th Edition 2The Worldwide Market for In Vitro Diagnostic Tests, 9th Edition 3
... COLLEGEVILLE, Pa., April 03, 2007 /PRNewswire-FirstCall/ --,Wyeth Pharmaceuticals, ... a,re- analysis of pooled data from both hormone ... published today in the,Journal of the American Medical ... coronary heart disease for women who,initiate hormone therapy ...
... superior sustained pain-free results compared to,sumatriptan, RESEARCH ... 03, 2007,/PRNewswire-FirstCall/ -- -- Findings from two ... sufferers demonstrated that,Trexima(TM) provided superior headache relief ... placebo, and two through 24-hour sustained,pain-free results ...
Cached Medicine Technology:New Analysis of Data from WHI Provides Reassurance With Respect to,Coronary Heart Disease For Newly Menopausal Women Considering,Hormone Therapy 2New Analysis of Data from WHI Provides Reassurance With Respect to,Coronary Heart Disease For Newly Menopausal Women Considering,Hormone Therapy 3New Analysis of Data from WHI Provides Reassurance With Respect to,Coronary Heart Disease For Newly Menopausal Women Considering,Hormone Therapy 4New Analysis of Data from WHI Provides Reassurance With Respect to,Coronary Heart Disease For Newly Menopausal Women Considering,Hormone Therapy 5New Analysis of Data from WHI Provides Reassurance With Respect to,Coronary Heart Disease For Newly Menopausal Women Considering,Hormone Therapy 6Trexima (Sumatriptan/Naproxen Sodium) Superior Efficacy Data,Published in JAMA 2Trexima (Sumatriptan/Naproxen Sodium) Superior Efficacy Data,Published in JAMA 3Trexima (Sumatriptan/Naproxen Sodium) Superior Efficacy Data,Published in JAMA 4Trexima (Sumatriptan/Naproxen Sodium) Superior Efficacy Data,Published in JAMA 5
... Screen Panel is used for the rapid detection of ... Panel consists of a test cup and test card. ... inserted and the sample sealed with a lid. Results ... to remove the test card to read the result. ...
Detect LH surge for predicting ovulation, Able to detect as low as 40 mIU/mL LH or 30 mIU/mL LH, Simple, easy and accurate, Built-in control system...
... Hemoglobin Test Systems provide ... quantitative hemoglobin results with ... a large hematology analyzer. ... of either the B-Hemoglobin ...
... Chemstrip Micral test strips are an ... in urine samples. When the test ... sample, urine passes via a wick ... albumin present in the sample binds ...
Medicine Products: