Navigation Links
Family history doubles aortic stenosis risk
Date:9/1/2013

Aortic stenosis is the most common heart valve disease in the elderly. It is associated with congenital bicuspid aortic valve and previous rheumatic heart disease, but is also often caused by calcification of a normal valve. Calcification of a normal valve may be associated with atherosclerotic changes in the portion of the aorta closest to the valve.

Dr Ranthe said: "Genetic factors may play a role in the development of aortic stenosis. A single nucleotide polymorphism in the lipoprotein(a) locus has been associated with aortic valve calcification and aortic stenosis.1 Elevated lipoprotein(a) is a risk factor for atherosclerosis, including ischaemic heart disease, which is known to aggregate in families. Our aim was to discover whether aortic stenosis also aggregates in families."

The study used information from national Danish registers and included the 4.2 million Danes born in or after 1920. The cohort was followed for more than 73 million person-years, starting in 1977 (the year the Danish Hospital Discharge Register began) and ending in 2012. Cases of aortic stenosis were recorded when they occurred at age 35 years or older.

Patients with any registration of a congenital heart defect and those with cardiovascular disease diagnosed at <35 years were excluded. Family history was defined as a first degree relative registered with aortic stenosis before the cohort member.

During the study period 29,983 patients were registered with aortic stenosis at age >35 years. Of those, 193 had a first degree relative with aortic stenosis and the relative risk was 2.04 (95% confidence interval [CI] 1.77-2.35). Dr Ranthe said: "The risk of aortic stenosis roughly doubled when patients had a first degree relative with the disease. In addition, aortic stenosis occurred earlier in life in patients with a family history of the condition."

The impact of family history differed between patients with and without ischaemic heart disea
'/>"/>

Contact: Celine Colas
press@escardio.org
44-773-005-7146
European Society of Cardiology
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Many Who First Misuse Prescription Pills Get Them From Friends, Family: Report
2. Treating childhood obesity: A family affair
3. No family history not a good reason for women 40-49 to stop yearly screening mammograms
4. May/June 2012 Annals of Family Medicine tip sheet
5. Fitness Fights High Blood Pressure, Even With Family History
6. Keeping Your Family Safe From Dog Bites
7. Viewers family background affects how they react to MTV shows 16 and Pregnant, Teen Mom
8. Does dinner make a strong family, or does a strong family make dinner?
9. Patient mental health overlooked by physician when a family member is present
10. New molecular structure offers first picture of a protein family vital to human health
11. Family first - caring within UK Bangladeshi and Pakistani communities
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/4/2015)... Each year, the Susan G. Komen organization hosts ... for breast cancer. This year, Dr. Mark Deutsch and his ... entertainment sponsor for the 25th annual Susan G. Komen Greater ... Lenox Square Mall. , The Komen organization hopes have 10,000 ... million. Perimeter Plastic Surgery has not only taken on the ...
(Date:5/4/2015)... “ LiveSchool ” was featured on ... a look at the latest and coolest applications on ... the host of AppWatch and technology expert, conducted the ... allows teachers to reward students with good behavior. , ... in the classroom. And the good people at ...
(Date:5/4/2015)... 04, 2015 The opportunity for children to ... are the motivating forces behind The Fairy Godmother Next Door, ... author Amy L. Stark. , The inspiration for the enchanting ... door comes from Stark’s desire to be a fairy godmother. ... fairy godmother to my neighbors’ children since they were born. ...
(Date:5/4/2015)... May 04, 2015 The U.S. healthcare ... boomers join the ranks of senior citizens (1) and ... an already over-burdened healthcare system. Additionally, as older healthcare ... replace them. Per the U.S. Census Bureau, the number ... increase 75% by 2050 while those 25 to 54 ...
(Date:5/4/2015)... WA (PRWEB) May 04, 2015 EyeCRO ... a collaboration to facilitate development of NM108, a first-in-class ... that lead to blindness, including Diabetic Retinopathy. The ... platform developed by EyeCRO, which can deliver drugs to ... topical eyedrop. , Under the terms of the ...
Breaking Medicine News(10 mins):Health News:Perimeter Plastic Surgery Sponsors 2015 Susan G. Komen Greater Atlanta "Race for the Cure" 2Health News:An Application for Teachers to Reward Students with Good Behavior Was Featured on NewsWatch Television 2Health News:Introducing New Children’s Book The Fairy Godmother Next Door 2Health News:U.S. Healthcare Worker Shortage Escalating: Sterling Warns Medical Practitioners to Rapidly Reverse Low Employee Retention 2Health News:U.S. Healthcare Worker Shortage Escalating: Sterling Warns Medical Practitioners to Rapidly Reverse Low Employee Retention 3Health News:U.S. Healthcare Worker Shortage Escalating: Sterling Warns Medical Practitioners to Rapidly Reverse Low Employee Retention 4Health News:EyeCRO and NeuMedics Announce Collaboration to Utilize MiDROPS™ Technology for the Development of NM108 2Health News:EyeCRO and NeuMedics Announce Collaboration to Utilize MiDROPS™ Technology for the Development of NM108 3
... (FEW) salutes the House of Representatives for approving ... federal worker provisions. An amendment was offered by ... include the Federal Employees Retirement System (FERS) Sick ... mark up of the bill. Subcommittee member Rep. ...
... levels rise in the wake of climate change and ... parts of the world are likely to be displaced. ... International Journal of Mathematics and Operational Research . ... Lethbridge, Alberta, Canada, and colleagues Ruhul Sarker of the ...
... Now Available to Other Food ManufacturersCHICAGO, April 1 ... new satiety water in New Zealand, called Whole. ... is a first for the market, and food ... other global markets can currently leverage the product,s ...
... Industry Leaders from Across the Country Gather to ... Performance ImprovementALEXANDRIA, Va., April 1 ... Care (IPC) solutions, recently concluded its highly successful ... for the GetWellNetwork community, GetConnected2009 ...
... Efforts are Rewarded for Third Consecutive YearOAKLAND, Calif., ... a "Climate Action Leader" for voluntarily calculating, verifying ... the California Climate Action Registry. This is the ... award from the Registry, a private, nonprofit organization ...
... Australian study suggests link to modifiable maternal habit, , , ... has replaced infants sleeping on their stomachs as the ... or SIDS, Australian researchers suggest. , They found that ... which awakens them in response to a life-threatening situation, ...
Cached Medicine News:Health News:FEW Salutes House for Passing Legislation with Federal Worker Provisions; FERS Sick Leave Credit and FERS Redeposit Approved 2Health News:FEW Salutes House for Passing Legislation with Federal Worker Provisions; FERS Sick Leave Credit and FERS Redeposit Approved 3Health News:Relocation, relocation, relocation 2Health News:Fonterra's New ClearProtein(TM) Satiety Water a First for New Zealand Market 2Health News:Fonterra's New ClearProtein(TM) Satiety Water a First for New Zealand Market 3Health News:Innovation and Sharing of Client Successes Highlight GetWellNetwork's GetConnected2009 Conference 2Health News:Innovation and Sharing of Client Successes Highlight GetWellNetwork's GetConnected2009 Conference 3Health News:Innovation and Sharing of Client Successes Highlight GetWellNetwork's GetConnected2009 Conference 4Health News:Kaiser Permanente Recognized for Efforts to Spread Health by Curbing Climate Change 2Health News:Kaiser Permanente Recognized for Efforts to Spread Health by Curbing Climate Change 3Health News:Kaiser Permanente Recognized for Efforts to Spread Health by Curbing Climate Change 4Health News:Mom's Smoking May Lead to SIDS 2
(Date:5/4/2015)... TAIPEI , May 4, 2015 ... partner, Merrimack Pharmaceuticals, Inc. (NASDAQ: MACK ) ... BAX ) jointly announced that Baxter has ... European Medicines Agency (EMA) for MM-398 (irinotecan liposome ... metastatic adenocarcinoma of the pancreas who have been ...
(Date:5/4/2015)... DOYLESTOWN, Pa. , May 4, 2015  Makindus, ... announced today that the European Medicines Agency (EMA) has ... for the treatment of Stargardt,s Disease. "We ... for MI-100 to treat Stargardt,s disease in place for ... our development program in the United States ...
(Date:5/4/2015)... Bayer HealthCare (Bayer) has entered into an ... ISIS ) on ISIS-FXI Rx, an antisense investigational ... Under the agreement Bayer will further develop and commercialize ... need. As part of the clinical development program, Bayer ... in an appropriate patient community. "Bayer ...
Breaking Medicine Technology:PharmaEngine Announces Filing by Baxter BioScience of Marketing Authorization Application of MM-398 (PEP02) to the European Medicines Agency for Post-Gemcitabine Metastatic Pancreatic Cancer Patients 2PharmaEngine Announces Filing by Baxter BioScience of Marketing Authorization Application of MM-398 (PEP02) to the European Medicines Agency for Post-Gemcitabine Metastatic Pancreatic Cancer Patients 3European Medicines Agency (EMA) Grants Orphan Designation for Makindus' MI-100 for Stargardt's Disease 2Bayer Licenses Investigational ISIS FXI(Rx) from Isis Pharmaceuticals to Develop and Commercialize for the Prevention of Thrombosis 2Bayer Licenses Investigational ISIS FXI(Rx) from Isis Pharmaceuticals to Develop and Commercialize for the Prevention of Thrombosis 3
... Delcath Systems, Inc. (Nasdaq: DCTH ) announced ... discuss its recent corporate developments and update its progress on ... President and Chief Executive Officer will host the call. ... 800-322-5044 for domestic participants and 617-614-4927 for international participants, both ...
... 2011 CVS Caremark Corporation (NYSE: CVS ... present at two investor conferences in the month of ... CVS Caremark, will be making a presentation to investors ... on Thursday, November 10th, at approximately 10:00 a.m. MST ...
Cached Medicine Technology:Delcath Systems to Report Third Quarter Progress and Conduct Conference Call 2Delcath Systems to Report Third Quarter Progress and Conduct Conference Call 3CVS Caremark to Present at Upcoming Conferences 2
Fahlbusch hypophysectomie instrument, spoon, bayonet-shaped, malleable....
... is pouncing on the T.L.I.F. market as the ... of CFRP clinical history and the amazing success ... Leopard is sure to be king of the ... from 7-18 mm in height. The footprint is ...
... Cage System provides anterior column support for ... from T1 to L5. The system consists ... Polymer cages that are stacked to a ... Peek Carbon Fiber Reinforced Polymer material emulates ...
... Jaguar Lumbar I/F Cage system is a ... separate the mechanical and biologic functions of ... Lumbar I/F Cage provides a device designed ... and uses autologous cancellous bone, the best ...
Medicine Products: