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Family History of Alcoholism May Raise Obesity Risk
Date:1/3/2011

MONDAY, Jan. 3 (HealthDay News) People at higher risk for alcoholism might also face higher odds of becoming obese, new study findings show.

Researchers at Washington University School of Medicine in St. Louis analyzed data from two large U.S. alcoholism surveys conducted in 1991-1992 and 2001-2002. According to the results of the more recent survey, women with a family history of alcoholism were 49 percent more likely to be obese than other women.

Men with a family history of alcoholism were also more likely to be obese, but this association was not as strong in men as in women, said first author Richard A. Grucza, an assistant professor of psychiatry.

One explanation for the increased risk of obesity among people with a family history of alcoholism could be that some people substitute one addiction for another. For example, after a person sees a close relative with a drinking problem, they may avoid alcohol but consume high-calorie foods that stimulate the same reward centers in the brain that react to alcohol, Grucza suggested.

In their analysis of the data from both surveys, the researchers found that the link between family history of alcoholism and obesity has grown stronger over time. This may be due to the increasing availability of foods that interact with the same brain areas as alcohol.

"Much of what we eat nowadays contains more calories than the food we ate in the 1970s and 1980s, but it also contains the sorts of calories -- particularly a combination of sugar, salt and fat -- that appeal to what are commonly called the reward centers in the brain," Grucza, explained in a university news release. "Alcohol and drugs affect those same parts of the brain, and our thinking was that because the same brain structures are being stimulated, overconsumption of those foods might be greater in people with a predisposition to addiction."

The study is published in the December issue of the journal
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