Navigation Links
Familial MS May Be More Destructive
Date:10/12/2007

Brain scans reveal more damage compared to sporadic cases

FRIDAY, Oct. 12 (HealthDay News) -- Multiple sclerosis that runs in families appears to cause more severe brain damage than the non-familial form, say University at Buffalo researchers.

They used MRI scans to examine the brains of 759 MS patients and found that the 198 patients with familial MS had significantly more destructed lesions, and significantly lower volume of whole brain, white matter and gray matter, as well as other indications of greater brain damage.

"Patients whose parents, children or siblings (first-degree relatives) had MS showed more damage than patients who had cousins with MS. This indicates that the closer the relationship, the greater the risk of MS," research team leader Dr. Robert Zivadinov, professor of neurology, said in a prepared statement.

"Of particular interest is the finding of more severe gray matter damage and more lesions, particularly in those with MS in first-degree relatives. These findings are very interesting, and we will be investigating them further," he added.

The study was to be presented Friday at a European Committee for the Treatment and Research in Multiple Sclerosis meeting in Prague, Czech Republic.

"From the early 1980s on, MS researchers thought that genetic factors likely played a role in the disease, that its traits were determined by several different genes, and our findings support this hypothesis," Zivadinov said.

"Our MRI analysis showed a difference between the severity of disease characteristics in familial MS patients versus what we call sporadic, or non-familial, MS patients. These differences may be related to some disease-modifying genes, but to prove this, we must do further investigation," he added.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about MS.



-- Robert Preidt



SOURCE: University at Buffalo, news release, Oct. 12, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Tobacco Found To Trigger Familial Pancreatic Cancer
2. Familial Breast cancer without gene mutation not found to cause ovarian cancer.
3. Obsessive-Compulsive Disorder Is Familial
4. Women Testing Negative for Familial Breast Cancer Gene Still at Increased Risk
5. Team Discovers a Gene That Causes Familial Pancreatic Cancer
6. Harm to the chest can be destructive
7. Internet Encourages Self-Destructive Behaviour Among Teens
8. Genetics Plays A Crucial Role In Preemies Destructive Eye Disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... Pixel Film ... Pro X. , "Film editors can give their videos a whole new perspective by ... Austin - CEO of Pixel Film Studios. , ProSlice Levels contains over 30 ...
(Date:6/25/2016)... ... June 25, 2016 , ... Experts from the American ... Annual Research Meeting June 26-28, 2016, at the Hynes Convention Center in Boston. ... including advance care planning, healthcare costs and patient and family engagement. , AIR ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , the largest ... as the Medical Director of its new Mesquite-Samuell Farm facility. , “We are ... Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First Choice Emergency ...
(Date:6/25/2016)... ... , ... Conventional wisdom preaches the benefits of moderation, whether it’s a matter ... bar too high can result in disappointment, perhaps even self-loathing. However, those who set ... , Research from PsychTests.com reveals that behind the tendency to set low ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Marcy was in a crisis. Her son James, ... out at his family verbally and physically. , “When something upset him, he couldn’t control ... use it. He would throw rocks at my other children and say he was going ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Research and Markets has announced the ... to 2022" report to their offering. ... patients with kidney failure, it replaces the function of kidneys ... blood and thus the treatment helps to keep the patient ... Increasing number of ESRD patients & substantial ...
(Date:6/23/2016)... , June 23, 2016 ... "Pharmaceutical Excipients Market by Type (Organic Chemical (Sugar, ... Formulation (Oral, Topical, Coating, Parenteral) - Global Forecast to ... The global pharmaceutical excipients market ... at a CAGR of 6.1% in the forecast period ...
(Date:6/23/2016)... 23, 2016 Roche (SIX: RO, ROG; OTCQX: ... its Elecsys BRAHMS PCT (procalcitonin) assay as a dedicated ... shock. With this clearance, Roche is the first IVD ... solution for sepsis risk assessment and management. ... and PCT levels in blood can aid clinicians in ...
Breaking Medicine Technology: