Navigation Links
Falling Platelet Counts May Signal HIV-Linked Dementia
Date:9/13/2007

Study finds a strong correlation, with risk doubling as blood cells decline

THURSDAY, Sept. 13 (HealthDay News) -- HIV-infected patients with declining blood platelet counts may be at increased risk for HIV-associated dementia, which causes a number of cognitive, behavioral and motor skill problems, researchers report.

Researchers at the Bloomberg School of Public Health at the Johns Hopkins University School of Medicine in Baltimore studied 396 patients with advanced HIV disease. Between 1998 and 2003, the patients were examined every six months, including mental and physical evaluations.

By the study midpoint of just over 31 months, 40 patients had developed HIV-associated dementia. The researchers found that a decline in platelet count from baseline at the start of the study was associated with the development of HIV-associated dementia within six to 12 months.

"Those HIV-infected individuals with a decline in platelets from baselines values at this lagged time point had a twofold increased risk of dementia," the study authors wrote.

"Further analyses indicated that decline from baseline platelet levels was associated with a five- to sixfold increased risk of dementia during the first two years of follow-up, but it was not associated with an increased risk of dementia after two years."

The authors said that it's "possible that individuals who do not progress rapidly to neurologic compromise differ in respect to immune activation, treatment adherence, or virologic control relative to those who develop dementia more rapidly."

They noted that CD4 cell counts and HIV RNA levels cannot be used to predict HIV-associated dementia. Further study of the link between platelet levels and HIV-associated dementia may lead to identification of a specific marker for this disease and how it develops.

The study is published in the September issue of the journal Archives of Neurology.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about neurological complications of AIDS.



-- Robert Preidt



SOURCE: JAMA/Archives journals, news release, Sept. 10, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Research on causes for falling helps develop preventive strategies
2. Diabetes on the Increase but Death Rate Falling
3. Diabetics increases likelihood of falling and associated accidental injury in elders
4. The Falling Sperm Count In Men
5. Government Takes Tough Stand Against Falling Sex Ratio
6. Smart Beds Could Help to Prevent Elderly Patients from Falling
7. Platelets May Be The Source Of Gene Regulations
8. Medicines Used In Antiplatelet Therapy Can Reduce Heart Attacks And Strokes
9. Quality Platelets and Improved Blood Availability No Longer a Pipe Dream
10. Automated Technique Accurately Measures Platelet Counts in "Platelet Gel" Products
11. Drug Boosts Platelet Production, Reversing Immune Thrombocytopenic Purpura
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2017)... ... May 24, 2017 , ... Patients who want to receive ... now meet with Dr. Joseph Bedich for a consultation, with or without a referral. ... oral health and functionality. , Dr. Bedich offers a variety of cosmetic ...
(Date:5/24/2017)... ... May 24, 2017 , ... Dr. ... of the HP3 (High-Performance Periodontal Practice) continuing education (CE) series. As a compassionate ... in his field by attending numerous CE courses each year. His recent course, ...
(Date:5/24/2017)... Brentwood, TN (PRWEB) , ... May 24, 2017 ... ... announced the addition of ExtraHop to its solutions portfolio. ExtraHop delivers an analytics-first ... and security of every IT system, from the datacenter to the cloud to ...
(Date:5/24/2017)... ... 2017 , ... Rob Lowe is a sought after actor, and also serves ... the public important topics from all aspects of life, and a new segment is ... feet and ankles. , Podiatry is essential to people’s overall well-being, and if viewers ...
(Date:5/24/2017)... (PRWEB) , ... May 24, 2017 , ... Technique, technique, ... back injury when either lifting weights for strength training and exercise or simply lifting ... Center . , “Body position is everything,” Dr. Chang says. “Improper technique in lifting ...
Breaking Medicine News(10 mins):
(Date:5/4/2017)... Clarius Mobile Health, a digital healthcare ... this week at the American Congress of Obstetricians ... San Diego, CA from May ... perfect tool for clinicians to easily confirm pregnancy, ... pregnancy-related complications like ectopic pregnancy and placenta previa," ...
(Date:5/4/2017)... 2017  DarioHealth Corp. (NASDAQ: DRIO), a leading global ... solutions, today announced that it is teaming up with ... Limited to lower diabetes healthcare costs in ... which is available throughout all provinces and territories in ... eligible for additional savings when shopping for Dario supplies ...
(Date:5/4/2017)... May 4, 2017   BioLife Solutions , Inc. ... and marketer of proprietary clinical grade hypothermic storage ... the "Company"), today announced that the Company,s first quarter ... on Thursday, May 11, 2017, and that the Company ... 1:30 p.m. PT that afternoon. Management will provide an ...
Breaking Medicine Technology: