Navigation Links
Factors Linked to Age of Onset of Menopause Identified
Date:1/26/2012

THURSDAY, Jan. 26 (HealthDay News) -- New genetic factors associated with a woman's age when she begins menopause have been identified by an international team of researchers.

Researchers identified 13 loci (specific location of a gene on a chromosome) linked with immune function and DNA repair, which have an effect on when menopause begins, said the researchers from the Boston University Schools of Public Health and Medicine and colleagues.

They also confirmed four previously established loci.

For most women, menopause -- the term for the end of reproductive function of the ovaries -- occurs in the early 50s.

The study was published online Jan. 22 in the journal Nature Genetics.

Most previous studies examining age of onset of menopause have zeroed in on genes associated with the estrogen-production pathway or vascular components, the researchers said.

"Our findings demonstrate the role of genes which regulate DNA repair and immune function, as well as genes affecting neuroendocrine pathways of ovarian function in regulating age at menopause, indicating the process of aging is involved in both somatic and germ line aging," the study authors said.

The new findings "bring us closer to understanding the genetic basis for the timing of menopause. They may also provide clues to the genetic basis of early onset or premature menopause and reduced fertility," team co-leader Kathryn Lunetta, a professor of biostatistics at the BU School of Public Health, said in a university news release.

"We hope that as a better understanding of the biologic effects of these menopause-related variants are uncovered, we will gain new insights into the connections between menopause and cardiovascular disease, breast cancer, osteoporosis and other traits related to aging, and that this will provide avenues for prevention and treatment of these conditions," Lunetta said.

More information

The U.S. National Institute on Aging has more about menopause.

-- Robert Preidt

SOURCE: Boston University Schools of Public Health and Medicine, news release, Jan. 23, 2012


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Retention study identifies key factors affecting 3 generations of nurses
2. Researchers Identify Liver Cancer Risk Factors
3. Mayo Clinic studies identify risk factors in rising trend of liver cancer
4. Demographic and clinical factors appear associated with survival in patients with Parkinsons disease
5. Risk Factors for Vision Loss After Spine Surgery Identified
6. Diagnosis, treatment of depression among elderly depend on racial, cultural factors
7. Association of lifestyle and environmental factors with the risk of cancer
8. Scientists identify strategies to conquer lifestyle and genetic factors related to chronic diseases
9. Risk factors for CCSVI are similar to risk factors for developing MS, UB study shows
10. Psychological factors affect IBS patients interpretation of symptom severity
11. Study identifies silent stroke risk factors for children with sickle cell anemia
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Factors Linked to Age of Onset of Menopause Identified
(Date:6/25/2016)... ... ... of Bruton Memorial Library on June 21 due to a possible lice infestation, as reported ... head lice: the parasite’s ability to live away from a human host, and to infest ... in the event that lice have simply gotten out of control. , As lice are ...
(Date:6/25/2016)... Oklahoma (PRWEB) , ... June 25, 2016 , ... ... both athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures ... Oklahoma City area —Johnson is one of the first doctors to perform the ...
(Date:6/24/2016)... Marne, Michigan (PRWEB) , ... June 24, 2016 , ... ... To deal with these feelings, many turn to unhealthy avenues, such as drug or ... Center of Marne, Michigan, has released tools for healthy coping following a traumatic event. ...
(Date:6/24/2016)... Fla. (PRWEB) , ... June 24, 2016 , ... Global ... Trend magazine’s 2016 Legal Elite. The attorneys chosen by their peers for this recognition ... Florida. , Seven Greenberg Traurig Shareholders received special honors as members of this year’s ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are ... Code Talker Award, an essay contest in which patients and their families pay tribute ... presented at the 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... , June 26, 2016 ... value-based care operating models within the health care industry ... greater financial efficiency , Deloitte offers a suite ... key business issues impacting efficient cost optimization: labor resource ... , These services facilitate better outcomes and better economics ...
(Date:6/24/2016)... , June 24, 2016   Bay ... Rehabilitation Network,s Dean Center for Tick Borne ... Medicine and Rehabilitation, MIT Hacking Medicine, University of ... Innovation, today announced the five finalists of ... Lyme disease.  More than 100 scientists, clinicians, researchers, ...
(Date:6/24/2016)... 2016 Dehaier Medical Systems Ltd. (NASDAQ: ... markets and sells medical devices and wearable sleep respiratory ... strategic cooperation agreement with Hongyuan Supply Chain Management Co., ... June 20, 2016, to develop Dehaier,s new Internet medical ... Dehaier will leverage Hongyuan Supply Chain,s sales platform to ...
Breaking Medicine Technology: