Navigation Links
Factors Linked to Age of Onset of Menopause Identified
Date:1/26/2012

THURSDAY, Jan. 26 (HealthDay News) -- New genetic factors associated with a woman's age when she begins menopause have been identified by an international team of researchers.

Researchers identified 13 loci (specific location of a gene on a chromosome) linked with immune function and DNA repair, which have an effect on when menopause begins, said the researchers from the Boston University Schools of Public Health and Medicine and colleagues.

They also confirmed four previously established loci.

For most women, menopause -- the term for the end of reproductive function of the ovaries -- occurs in the early 50s.

The study was published online Jan. 22 in the journal Nature Genetics.

Most previous studies examining age of onset of menopause have zeroed in on genes associated with the estrogen-production pathway or vascular components, the researchers said.

"Our findings demonstrate the role of genes which regulate DNA repair and immune function, as well as genes affecting neuroendocrine pathways of ovarian function in regulating age at menopause, indicating the process of aging is involved in both somatic and germ line aging," the study authors said.

The new findings "bring us closer to understanding the genetic basis for the timing of menopause. They may also provide clues to the genetic basis of early onset or premature menopause and reduced fertility," team co-leader Kathryn Lunetta, a professor of biostatistics at the BU School of Public Health, said in a university news release.

"We hope that as a better understanding of the biologic effects of these menopause-related variants are uncovered, we will gain new insights into the connections between menopause and cardiovascular disease, breast cancer, osteoporosis and other traits related to aging, and that this will provide avenues for prevention and treatment of these conditions," Lunetta said.

More information

The U.S. National Institute on Aging has more about menopause.

-- Robert Preidt

SOURCE: Boston University Schools of Public Health and Medicine, news release, Jan. 23, 2012


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Retention study identifies key factors affecting 3 generations of nurses
2. Researchers Identify Liver Cancer Risk Factors
3. Mayo Clinic studies identify risk factors in rising trend of liver cancer
4. Demographic and clinical factors appear associated with survival in patients with Parkinsons disease
5. Risk Factors for Vision Loss After Spine Surgery Identified
6. Diagnosis, treatment of depression among elderly depend on racial, cultural factors
7. Association of lifestyle and environmental factors with the risk of cancer
8. Scientists identify strategies to conquer lifestyle and genetic factors related to chronic diseases
9. Risk factors for CCSVI are similar to risk factors for developing MS, UB study shows
10. Psychological factors affect IBS patients interpretation of symptom severity
11. Study identifies silent stroke risk factors for children with sickle cell anemia
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Factors Linked to Age of Onset of Menopause Identified
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: the Christian history of ... Brink” is the creation of published author, William Nowers. Captain Nowers and his ... veteran, he spent thirty years in the Navy. Following his career as a ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... treating sleep apnea using cutting-edge Oventus O2Vent technology. As many as ... disorder characterized by frequent cessation in breathing. Oral appliances can offer significant relief ...
(Date:10/12/2017)... ... 12, 2017 , ... The company has developed a suite ... regulatory authorities worldwide. From Children’s to Adults 50+, every formula has been developed ... , These products are also: Gluten Free, Non-GMO, Vegan, Soy Free, Non-Dairy*, ...
(Date:10/12/2017)... ... ... The American College of Medical Informatics (ACMI) will present the 2017 Morris ... of AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual Symposium is taking ... in the field of medical informatics, this prestigious award is presented to an individual ...
(Date:10/12/2017)... ... October 12, 2017 , ... Information about the technology: , ... to enable prevention of a major side effect of chemotherapy in children. Cisplatin ... patients. For cisplatin, hearing loss is FDA listed on-label as a dose limiting ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... , Oct. 12, 2017   Divoti USA ... Jewelry up to the standard of the latest FDA requirements, which ... 2017). Anyone in need of Medical ID jewelry such ... Alert Jewelry are engraved in terms of the new ... Divoti offers ...
(Date:10/11/2017)... 11, 2017  True Health, a leader in ... effort during National Breast Cancer Awareness month to ... Research recently ... that more than 10 million American women are ... BRCA1 or BRCA2 and have not had testing. These ...
(Date:10/7/2017)...   Provista, a proven leader in the ... purchasing power, today announced a new resource area on ... is the online home for case studies, articles ... news releases, slideshows and events. ... resources at their fingertips, viewers can also watch short ...
Breaking Medicine Technology: