Navigation Links
Facet Biotech and Trubion Announce Worldwide Collaboration for the Development and Commercialization of TRU-016
Date:8/28/2009

ncing this important program with our partners at Trubion."

"In considering alliance opportunities for TRU-016 we sought to retain meaningful economics in this exciting first-in-class product candidate, while enabling aggressive joint development with a partner who shared our vision and brought complementary experience and resources to the alliance," said Peter Thompson, M.D., FACP, president, CEO and chairman of Trubion. "We are delighted to have Facet as our partner. Coupled with our own strengths in the discovery and development of novel protein therapeutics, their expertise will afford us the opportunity to pursue the clinical development and commercialization of TRU-016 and other CD37-directed therapeutics in the most aggressive manner possible."

Under the terms of the collaboration agreement, Trubion will receive an upfront payment of $20 million and may receive up to $176.5 million in additional contingent payments upon the achievement of certain development, regulatory and sales milestones. The companies will share equally the costs of all development, commercialization and promotional activities and all global operating profits. In addition, Facet will purchase 2,243,649 shares of newly issued Trubion common stock for an aggregate purchase price of $10 million.

About TRU-016

TRU-016 is a novel CD37-directed therapy for the treatment of B-cell malignancies, such as chronic lymphocytic leukemia, or CLL, as well as certain autoimmune and inflammatory disease indications. TRU-016 uses a different mechanism of action than CD20-directed therapies. As a result, its novel design may provide patients with improved therapeutic options and enhance efficacy when used alone or in combination with chemotherapy and/or CD20-directed therapeutics. In June 2009, positive results following preliminary analysis from the Phase 1 clinical trial of TRU-016 for the treatment of CLL were announced. The object
'/>"/>

SOURCE Trubion Pharmaceuticals Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine news :

1. Facet Solutions Completes 1 Year Follow-up on U.S. Pilot Study
2. The Help Group Launches Multifaceted Autism Awareness Campaign
3. Perrigo Announces FDA Approval for Sulfacetamide Sodium Topical Suspension USP, 10% (Lotion)
4. Archus Orthopedics Performs First Facet Replacement Procedure With an Artificial Disc
5. Facet joint effusion and interspinal ligament edema: major sources of lower back pain
6. TruFUSE(R) Minimally Invasive Facet Fusion Procedure Tops 3,000 Spinal Levels
7. Facet Solutions, Inc. Completes Combination Facet Joint and Disc Replacement Study
8. Facet Solutions, Inc. Appoints Industry Veteran to Board of Directors
9. Facet Solutions, Inc. Expands Executive Management Team
10. Journal of Alzheimers Disease special issue explores multifaceted aspects of AD
11. Facet Solutions AFRS(TM) Implant Demonstrates Positive Clinical Results After One Year Follow Up
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... Memantine was initially developed by Merz to ... under the brand name Akatinol; it was later licensed to ... in the USA to Forest Labs as Namenda. Lundbeck reported ... In the US, Forest reported Namenda sales of USD 1.5 ... Australia and the European region has increased the competition from ...
(Date:7/24/2014)... it is possible to predict long-term cancer risk from a ... exposure. The findings, which currently appear in the journal ... and cheaper tests to screen chemicals for their potential cancer ... incidence of and mortality from cancer, about 40 percent of ... and around 20 percent will die of it. Currently fewer ...
(Date:7/24/2014)... Lynn E. Taylor, M.D., director of The ... the July, 2014 Rhode Island Medical Journal ... eliminating hepatitis c virus infection (hep c or ... capacity to address other health challenges, and improve ... the United States, Taylor says, include lack of ...
(Date:7/24/2014)... News) -- Giving low-income families vouchers to buy fruits ... of these healthy foods, according to a new study. ... vegetables. In addition to not having adequate access to ... vouchers could help address both of these obstacles, the ... farmers, market incentives may be able to bring a ...
(Date:7/24/2014)... Could the body,s own immune system play a role ... like chronic epilepsy, Alzheimer,s dementia and concussions? Cleveland Clinic ... by PLOS ONE . , The study focuses ... which serves as a biomarker for brain damage. Normally, ... column. However, following a brain injury, it can leak ...
Breaking Medicine News(10 mins):Health News:Memantine Discussed in New Comprehensive Patent Search Report by Ark Patent Intelligence Published at MarketPublishers.com 2Health News:Memantine Discussed in New Comprehensive Patent Search Report by Ark Patent Intelligence Published at MarketPublishers.com 3Health News:Researchers discover new way to determine cancer risk of chemicals 2Health News:Miriam Hospital physician advocates awareness, collaboration to combat peaking hep C virus 2Health News:Miriam Hospital physician advocates awareness, collaboration to combat peaking hep C virus 3Health News:Miriam Hospital physician advocates awareness, collaboration to combat peaking hep C virus 4Health News:Farmers' Market Vouchers May Help Poorer Families Eat Healthier 2Health News:Immune response may cause harm in brain injuries, disorders 2
... HealthDay Reporter , TUESDAY, July 13 (HealthDay News) -- ... major Alzheimer,s conference describe progress in a series of ... the two major proteins implicated in Alzheimer,s disease. ... typically taken a backseat to another protein, the beta ...
... patches and gum are common ― and often ineffective ... have discovered. Now a new study from Tel Aviv ... basis for more successful psychologically-based smoking cessation programs. ... of Abnormal Psychology , Dr. Reuven Dar of Tel ...
... surviving by a whisker. The most common type of stroke can ... to a new study by UC Irvine researchers. Strokes are ... disease and cancer. About 795,000 Americans suffer them annually, according to ... result. So should we be tickling our own whiskers? And ...
... HealthDay Reporter , TUESDAY, July 13 (HealthDay News) -- ... decade ago that the blockbuster diabetes drug caused an increased ... to a report published Tuesday in The New York ... its competitor, Actos, the drug company, then known as SmithKline ...
... the locker room with a dislocated shoulder wouldn,t care whether ... female -- or would he? A study from North Carolina ... trainers and their comfort level in being treated by ... a male, unless the dislocated shoulder made him depressed. ...
... lose significantly less bone mineral content (BMC) as they age ... research in the July issue of BJUI . The ... key role in the development of fragile bones, fractures and ... Baltimore Longitudinal Study at an average age of 56 between ...
Cached Medicine News:Health News:Alzheimer's Research Spotlights Protein 'Tangles' in Brain 2Health News:Alzheimer's Research Spotlights Protein 'Tangles' in Brain 3Health News:Smoking mind over smoking matter 2Health News:Smoking mind over smoking matter 3Health News:Whisker stimulation prevents strokes in rats, UCI study finds 2Health News:Avandia Heart Risks Buried by Drug Company: Report 2Health News:Avandia Heart Risks Buried by Drug Company: Report 3Health News:Locker room talk: How male athletes portray female athletic trainers 2Health News:High-risk prostate cancer associated with significantly lower bone mineral content loss 2
(Date:7/24/2014)... , July 24, 2014 /PRNewswire-iReach/ -- Delivery of ... order is placed. Photo - ... professional and in-depth market survey on Global and ... the basic information of Hemodialysis Machine including its ... explores global and China,s top manufacturers of Hemodialysis ...
(Date:7/24/2014)... July 24, 2014   Royal Philips (NYSE: ... it has received 510(k) clearance from the U.S. Food ... ultrasound system, VISIQ, in the U.S. VISIQ ... benefits of greater mobility, performance and simplicity into a ... diagnostic scans for more OB patients. This ...
(Date:7/24/2014)... 24, 2014  Bruin Biometrics (BBI), a pioneer ... after two weeks of clinical briefings to over ... it gained substantial concurrence on both the clinical ... utility of BBI,s SEM Scanner. ... the respondents drawn from the European Wound Management ...
Breaking Medicine Technology:Hemodialysis Machine Industry for Global and Chinese Markets Forecast to 2019 2Hemodialysis Machine Industry for Global and Chinese Markets Forecast to 2019 3Hemodialysis Machine Industry for Global and Chinese Markets Forecast to 2019 4Hemodialysis Machine Industry for Global and Chinese Markets Forecast to 2019 5Philips receives FDA 510(k) clearance for its innovative ultra mobile VISIQ ultrasound system 2Philips receives FDA 510(k) clearance for its innovative ultra mobile VISIQ ultrasound system 3Bruin Biometrics Secures Support of EU Scientific Community for its SEM Scanner Technology 2
... , Consumers Oppose Prescription Mandate; Prefer Alternative Method to ... Jan. 30 Mississippians are expressing outrage at lawmakers, ... (PSE) to a prescription (Rx) drug. , "The Consumer ... Mississippians to contact their legislators which within the first day ...
... Jan. 29 The IKF,s (International Kids Fund) ... Children called the " Haiti ,s Children Fund."  It will ... Memorial Hospital for life-saving medical care.  Donations may be made ... program of the Jackson Memorial Foundation, whose mission is to ...
Cached Medicine Technology:Mississippians React to Rushed Pseudoephedrine Debate Raging in the State Legislature 2Mississippians React to Rushed Pseudoephedrine Debate Raging in the State Legislature 3IKF's Wonderfund(TM) Needs Support for Haiti's Children 2
CRP Liquid Conrtols level 2...
The AMY method used on the Dimension clinical chemistry system is an in vitro diagnostic test intended for the quantitative determination of amylase activity in serum, plasma and urine....
The GLU method used on the Dimension clinical chemistry system is an in vitro diagnostic test intended for the quantitative determination of glucose in serum, plasma, urine and cerebrospinal fluid....
Enzymatic Clearance assay for the in vitro quantitative determination of LDL-cholesterol in human serum and plasma....
Medicine Products: