Navigation Links
FDR Might Have Had Melanoma
Date:4/25/2008

Researcher suggests large lesion above his left eyebrow was possibly skin cancer

FRIDAY, April 25 (HealthDay News) -- Though shrouded in secrecy during his lifetime, historians have gone to great lengths to posthumously chronicle the mysterious circumstances surrounding the health of Franklin Delano Roosevelt, the 32nd president of the United States.

That he suffered from both polio and heart disease is now well-documented. But a new study suggests that he may also have had -- and possibly even died from -- melanoma.

"I'm not stating unequivocally that he had melanoma," said study author Dr. A. Bernard Ackerman, director of the Ackerman Academy of Dermatopathology in New York City. "But it sure looks like it."

The source of the supposition is the 30-year presence of a pigmented lesion above FDR's left eyebrow -- a mark that appears in innumerable photographs.

Ackerman presents his case in the April issue of the Archives of Dermatology. However, he acknowledges that proving or disproving the contention amounts to a practical impossibility, given that at FDR's death an autopsy was never conducted, and that the lesion in question was never biopsied.

"The only way to prove it is to do a biopsy," he said. "So it could be that it was a sunspot, an age spot, a liver spot -- all synonyms for 'solar lentigo'. We don't know. But I will say that it is something that any competent doctor today would look at and say reflexively is melanoma."

FDR died at the age of 63 on April 12, 1945, shortly after flying a strenuous 14,000 miles to attend the now famous Yalta Conference -- a key meeting held between himself, Winston Churchill and Joseph Stalin, leading up to the end of World War II.

At the time, the cause of death was declared to be a cerebral hemorrhage, most probably associated with high blood pressure.

Yet most of FDR's medical records are missing. And contemporaneous efforts taken by FDR's personal physician -- Dr. Ross T. McIntire -- to preserve FDR's medical privacy were legendary and thorough.

Most of the American public, for one, had no idea that FDR had contracted polio in 1921, and that throughout his 12 years at the White House he was unable to walk without assistance.

That said, nothing by way of written proof has ever surfaced to suggest that FDR had melanoma or died of the disease.

But, as Ackerman points out, this is no surprise given that "no one would have ever suspected melanoma at that period in time."

"This to me is one of the most fascinating and gripping aspects of this case," said Ackerman. "Here's a man who is one of the most photographed men in the world, walking around in public daily with something that looks like a melanoma on his face. And no one says a word. Because going back to the 1930s and '40s, no one knew what it was."

Melanoma is a cancer of the thin top layer of the skin, called the epidermis, which strikes the melanocyte cells that are responsible for the brown protective pigmentation that emerges following sun exposure. According to the American Cancer Society, melanoma accounts for about 3 percent of all skin cancer cases in the United States, and that more than 62,000 Americans will be diagnosed with the disease this year. But it causes most skin cancer deaths -- about 8,420 Americans will die of this disease this year.

Melanoma is usually curable if caught early. The appearance of new moles or freckles or visible changes in skin patterns is sometimes, but not always, an early indicator of trouble. To conduct self-screening, doctors suggest following the so-called "ABCDE" rule.

Such a self-exam focuses on several factors: "Asymmetry" (when one half of a mole is different from the other half); "Border irregularity" (when the edges are irregular); "Color" (when the shading is not uniform); "Diameter" (when the mole is larger than one-quarter of an inch in size); and "Elevation" (when the mole is raised or bumpy).

Ackerman and his study co-author, Dr. Steven Lomazow, of the Mount Sinai School of Medicine in New York City, pointed out that FDR's mole -- which was about one inch by three-quarters of an inch at its largest stage -- does check off as suspicious on all aspects of the ABCDE criteria.

Nevertheless, they also admit that a range of other pigmented lesions could have accounted for the marking's characteristics.

And Dr. Vijay Trisal, an assistant professor of surgical oncology at the City of Hope Cancer Center in Duarte, Calif., said that he was not persuaded by visual evidence that FDR had melanoma or died of the disease.

"First of all, what you have to understand is that in this country today, out of every hundred lesions we think are suspicious for melanoma, only one is a melanoma and the rest are nothing," he noted. "And with a purely visual diagnosis, in most cases we can get only a 5 percent accuracy."

"Specifically with respect to FDR's case," he added, "I would say given the size of the lesion and the irregular color pattern, there is a 30 or 40 percent range of accuracy in visually diagnosing it."

Such hesitancy aside, Trisal suggested that if FDR indeed had melanoma it was probably not life-threatening.

"It seems more like a less aggressive 'lentigo-maligna' type of melanoma," he said. "One that typically grows slowly, with little effect on longevity.

"So I don't get the feeling that they [the study authors] made a strong argument about melanoma being the cause of death," Trisal concluded.

More information

For additional information on melanoma, visit the American Cancer Society.



SOURCES: A. Bernard Ackerman, M.D., director, Ackerman Academy of Dermatopathology, New York City; Vijay Trisal, M.D. assistant professor, surgical oncology, City of Hope Cancer Center, Duarte, Calif.; April 2008, Archives of Dermatology


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Fish Oil Might Help Relieve MS
2. HIV Drug Might Fight Cancer
3. High and mighty: first common height gene identified by researchers behind obesity gene finding
4. Vitamin C Plus Fat Might Spur Cancer
5. Mathematics might save you a trip to the ER
6. Veggies Might Ward Off Age-Linked Vision Woes
7. Rating your pain from 0 to 10 might not help your doctor
8. Blood Marker Might Help Spot Early Liver Cancer
9. Hushed Genes Might Mean Higher Lung Cancer Risk
10. Mathematics might save you a trip to the ER
11. More Prostate Cancers Might Be Prevented
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/16/2017)... , ... August 16, 2017 , ... Fusion Flix Inc., ... original programming over four countries and millions of viewers in a partnership with the ... or buy On-Demand and fully available on Blu Ray disc in 2018. Proceeds will ...
(Date:8/16/2017)... Utah (PRWEB) , ... August 16, 2017 , ... Connexion ... the Inc 5000 list for the fourth consecutive year. With 197% revenue ... 2017 list of the nation’s fastest growing companies. , Previous honors include ...
(Date:8/16/2017)... Ridge, NJ (PRWEB) , ... August 16, 2017 ... ... Hills is offering an opportunity for men and women to train as ... their families dealing with life-limiting illness. For over 30 years, the agency has ...
(Date:8/16/2017)... ... 16, 2017 , ... As part of the Arrow Wellness ... their local business community, Riverfront Fitness is the first of many recipients vying ... integral part of treating those suffering from sudden cardiac arrest in the few ...
(Date:8/16/2017)... ... , ... With low back pain afflicting 8 of 10 Americans at some point in their ... back pain. But this equally vexing condition stems from a variety of causes that can ... PhD , founder and president of Atlantic Spine Center. , Nestled between your neck ...
Breaking Medicine News(10 mins):
(Date:8/15/2017)... HOUSTON , Aug. 15, 2017   Mostyn Law ... in Houston, Texas . The Mostyn Law ... the past 2 years. That is why Mostyn Law ... Texas to show its appreciation. Blood supplies ... to fall 5% short of hospital needs in August. That is ...
(Date:8/15/2017)... Diplomat Pharmacy, Inc. (NYSE: DPLO), is now ... residents. Naloxone is available without a ... pharmacy, G-3320 Beecher Road. ... Administration, is intended to block or reverse the effects ... of consciousness. The medication is often carried by first ...
(Date:8/15/2017)... HIGH POINT, N.C. , Aug. 15, 2017  Axium Pharmaceuticals Inc., ... epilepsy is rumored to be in the beginning stages of an IPO. ... billion annually on epilepsy medications with the average cost of a prescription ... ... Another staggering figure is ...
Breaking Medicine Technology: