Navigation Links
FDA approves new drug for advanced melanoma
Date:3/25/2011

BOSTON--The U.S. Food and Drug Administration today approved the use of ipilimumab for the treatment of previously treated metastatic melanoma. It is the first drug approved for metastatic, or advanced, melanoma is more than a decade.

"Ipilimumab is the first in a new class of drugs that has been shown to offer a survival benefit for metastatic melanoma, which is often a fatal disease, and hopefully, this will lead to the development of related treatments for other cancers," said F. Stephen Hodi, MD, director of the melanoma treatment center at Dana-Farber Cancer Institute and a lead investigator of the national clinical study of ipilimumab.

The number of cases of metastatic melanoma, considered to be one the most serious form of skin cancer, has increased during the past 30 years, and its death rate is rising faster than most other cancers. The American Cancer Society estimated that the disease was diagnosed in more than 68,000 Americans and be responsible for 8,700 deaths in this country in 2010.

Ipilimumab, developed by Bristol-Myers Squibb and Medarex, is a monoclonal antibody that consists of millions of copies of a human antibody that binds to CTLA-4 protein molecule on T cells white blood cells that patrol the body for signs of illness. CTLA-4 serves as a control switch for the immune system's response to disease. With no antibody attached, CTLA-4 suppresses the immune response. Ipilimumab reverses that condition, unleashing the immune attack on abnormal cells, including cancer cells.

Last year, Hodi reported at the annual meeting of the American Society of Clinical Oncology and in the New England Journal of Medicine findings from a phase III trial involving 676 patients with advanced (stage III or IV), inoperable melanoma that had worsened during prior therapy for metastatic disease.

Patients were randomly assigned to receive one of three treatment regimens: ipilimumab and the gp100 vaccine (which seeks t
'/>"/>

Contact: Bill Schaller
william_schaller@dfci.harvard.edu
617-632-5357
Dana-Farber Cancer Institute
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Kaiser Permanente Approves $170 Million in Community Benefit Grants in 2009
2. The American Association of Anatomists approves guidelines for body donation programs
3. Golden Meditech Shareholders Approves of Name Change
4. New Jersey Approves Initiative to Expand the Number of Wound Care Certified Professionals
5. Congress Approves Bill Curbing Internet Tobacco Sales in Victory for Kids and Taxpayers
6. House of Representatives Approves Health-Care Reform Bill
7. New York State Office of Mental Health Approves New High Performance Polycarbonate Sheet for Use in All Facilities
8. FDA Approves Stemedica IND for Ischemic Stroke Clinical Trial
9. FDA approves first human neural stem cell clinical trial to treat brain tumors
10. Early detection of cancer: The FDA approves procedure discovered by EPFL researchers
11. FDA approves Merz Pharmaceuticals Xeomin (incobotulinumtoxinA) for the treatment of cervical dystonia and blepharospasm
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
FDA approves new drug for advanced melanoma
(Date:7/2/2015)... ... 02, 2015 , ... sweetFrog Enterprises, LLC. is pleased to announce the opening of its newest ... Lone Star State. The premium frozen yogurt chain was listed as #22 on the Inc. ... in the Village at Bachman Lake, is located at:, 3701 W. Northwest Highway, STE 430, ...
(Date:7/2/2015)... ... ... the recent report by JAMA Internal Medicine published on June 22, 2015, ... declared a war on obesity in the United States. , "Obesity is one of ... magnitude of this discovery. For that reason, I am declaring, along with my Health ...
(Date:7/2/2015)... ... 02, 2015 , ... When Walker Parking Consultants specified Kenall ... Minnesota, they knew it would save the university energy and maintenance costs. What ... total energy savings after installation was an impressive 89 percent, which resulted in ...
(Date:7/2/2015)... ... ... full swing, Americans are flocking to Canada’s many lakes to reel in their fair share ... and it’s easy to understand why. From the Pacific Northwest Coast of British Columbia to ... a huge industry, and Americans make up the vast majority of anglers from outside of ...
(Date:7/2/2015)... ... ... LIFX ” was featured on NewsWatch as part of its monthly Tech Report, which ... expert and special reporter for NewsWatch, conducted the review and shared with viewers how ... According to the U.S. Department of Energy, it’s very important to use energy-efficient light ...
Breaking Medicine News(10 mins):Health News:sweetFrog Opens 18th Location in the Lone Star State 2Health News:Samir Becic's Health Fitness Revolution Declares War Against Obesity in America 2Health News:Samir Becic's Health Fitness Revolution Declares War Against Obesity in America 3Health News:Samir Becic's Health Fitness Revolution Declares War Against Obesity in America 4Health News:Kenall’s TekDek™ Helps University Achieve Award-Winning Energy Savings in Parking Structure Lighting Retrofit 2Health News:The Most Versatile Smart Light Bulbs were featured on NewsWatch Television 2
... increased over the past years with more than one-third ... alternative medicine. Alternative or complementary therapies include treatments such ... vitamins. ,Researchers in Boston compared the results ... National Health Interview Survey taken in 2002. Results showed ...
... disorder, where white blood cells attack fatty tissue surrounding nerve ... is twice as common in women as in men . ... with multiple sclerosis. Since MS causes muscle weakness and fatigue, ... of life, researchers designed an exercise program to develop ...
... in as little as two days of physical inactivity, the ... and other related diseases.// ,Researchers conducted a study in ... stayed inactive. When the rats stopped running for two days ... of sugar taken into the muscle in response to insulin ...
... children who have Duchenne muscular dystrophy (DMD) with the oral ... despite the side effects of the drug . Most patients ... teens or early 20s from respiratory failure or heart problems. ... questioned whether its side effects, which can range from weight ...
... carry a gene that produces a higher level of ... for stroke.// ,Researchers reviewed medical literature on homocysteine ... study results were observational in nature. A standard scientific ... looking at data on the link between homocysteine and ...
... disease who follow a heart-healthy diet and weight-loss regimen ... that raise HDL (high-density lipoproteins or "good" cholesterol) levels, ... patients younger than 76 with low HDL and known ... a heart-healthy diet and lost weight. However, results showed ...
Cached Medicine News:
(Date:7/2/2015)... Ill. , July 2, 2015  AbbVie (NYSE: ... results on Friday, July 24, 2015, before the market ... of the earnings conference call at 8 a.m. Central ... AbbVie,s Investor Relations website at www.abbvieinvestor.com . An ... 11 a.m. Central time. About AbbVie ...
(Date:7/2/2015)... Wash. , July 2, 2015   BioLife Solutions ... and marketer of proprietary clinical grade cell and tissue ... a related cloud hosted biologistics cold chain management app ... today announced that Seattle Business Magazine has included ... to work for in Washington state ...
(Date:7/2/2015)... July 2, 2015 BGI announced today that ... Kong has been accredited by the American ... the first clinical next-generation-sequencing laboratory to receive the CAP ... highest standard in clinical laboratory practices. Complementary to the exiting ... process, and multiple ISO certifications, the CAP certification enables ...
Breaking Medicine Technology:BioLife Solutions Named One of the 100 Best Companies to Work For in Washington State 2BioLife Solutions Named One of the 100 Best Companies to Work For in Washington State 3BGI Receives Accreditation from the College of American Pathologists (CAP) 2
... Inc., a pioneer in the area of digital PCR, is ... to evaluate the capabilities of digital PCR and see the ... will start on Monday, September 12 in Boston and finish ... The QuantaLife ddPCR System claims to be the world,s most ...
... SILVER SPRING, Md., Aug. 26, 2011 The FDA ... ensuring the safety of their food and medical supplies ... week,s expected hurricane-related rain, possible flooding and power outages. ... The agency also reminds consumers that it is important ...
Cached Medicine Technology:QuantaLife™ Kicks Off Droplet Digital™ PCR Road Show 2FDA Hurricane Preparedness Checklist 2FDA Hurricane Preparedness Checklist 3FDA Hurricane Preparedness Checklist 4
... Electrohydraulic Lithotriptor combines efficient stone fragmentation, low ... a large, clear LED display, automatic probe ... according to probe size. In addition, the ... end-of-life, and can also regulate and control ...
Electrohydraulic Lithotripsy Probe for AEH-2 & AEH-3...
Short double-horn bridge for insertion of instruments...
Only SurLok combines precise control, enhanced basket and grasper strength, and the added security of a unique wire-locking mechanism. You can feel the difference. The SurLok flat-wire and grasper ha...
Medicine Products: