Navigation Links
FDA approves VYVANSE, first and only once-daily prodrug stimulant to treat ADHD in adults
Date:4/23/2008

July 2007, the product has achieved a U.S. market share of 6.9 percent based on weekly branded prescription volume VYVANSE formulary coverage has been positive, with the top six managed care plans now covering the product in a preferred formulary position.

VYVANSE is a therapeutically inactive prodrug, in which d-amphetamine is covalently bonded to l-lysine, and after oral ingestion it is converted to pharmacologically active d-amphetamine. The conversion of VYVANSE to d-amphetamine is not affected by gastrointestinal pH and is unlikely to be affected by alterations in normal GI transit times.

VYVANSE is currently available in three dosage strengths of 30 mg, 50 mg and 70 mg, each for once-daily dosing. Additional dosage strengths of 20 mg, 40 mg and 60 mg VYVANSE have also been FDA-approved and are expected to be available in pharmacies this summer.

Additional information about VYVANSE and Full Prescribing Information are available at www.vyvanse.com.

VYVANSE Significantly Improved ADHD Symptoms

The phase III pivotal trial that led to the FDA approval of VYVANSE to treat adults with ADHD was a double-blind, placebo-controlled, four-week study with dose escalations in 414 adults aged 18 to 55 years. In this study, adults with ADHD experienced significant improvements in ADHD symptom control within one week of treatment with once-daily VYVANSE.

Treatment with VYVANSE at all doses studied (30 mg, 50 mg, 70 mg) was significantly more effective than placebo, providing a reduction in ADHD Rating Scale (ADHD-RS-IV) scores ranging from 16.2 to 18.6 points at endpoint. The ADHD-RS-IV is a standardized test for assessing symptoms of ADHD and for assessing their response to treatment. This scale, which contains 18 items, is based on the ADHD diagnostic criteria as defined in the APAs Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision, a pu
'/>"/>

Contact: Matthew Cabrey, Shire
484-595-8248
Porter Novelli
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. FDA Approves First Anti-Psychotic for Kids
2. FDA Approves New Roche West Nile Virus Blood Screening Test
3. FDA Approves Osteoporosis Drug to Cut Breast Cancer Risk
4. FDA Approves LEVAQUIN(R) Short-Course Therapy for Treatment of Complicated Urinary Tract Infections and Acute Pyelonephritis
5. FDA Approves SOMA(R) (carisoprodol) 250 mg
6. FDA Approves Expanded Label for FluMist(R) to Include Children Two to Five Years of Age
7. FDA approves expanded label for FluMist (influenza virus vaccine live, intranasal) to include childr
8. FDA Approves Expanded Labeling for Campath(R) to Include First-line Treatment for Leading Form of Adult Leukemia
9. ABIH Approves Certification Credit for SSPC Training Courses
10. FDA Approves REALIZE(TM) Adjustable Gastric Band for Morbid Obesity
11. FDA Approves New Flu Vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... January 23, 2015 AngelWeddingDress, the premier ... 2015 maternity wedding dresses. View website of ... looking for maternity wedding dresses online for a bridal ... with high quality for them. Its maternity wedding dresses ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Autocarinsurancebest.com has released ... purchasing a commercial auto insurance policy . , Auto ... their vehicles. It is no longer necessary to call an ... are now available online on a single website: http://autocarinsurancebest.com/ ...
(Date:1/22/2015)... January 22, 2015 Yesterday, Senator ... (D-Concord) and Kristin Olsen (R-Modesto) were honored by ... in advancing biotechnology, biomedical science, medical device and ... each received the “2014 Life Sciences Champion” award ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 EBSCO Information ... (AMA) are expanding their relationship in an effort to further ... the world. While EBSCO has long made AMA journals available ... sales agent for The JAMA Network. , Long ...
(Date:1/22/2015)... Step into a macabre world where plants hold ... Wicked Plants, the Museum’s latest featured exhibition, opens Saturday, ... and diabolical plants inside of a dilapidated, Victorian home. ... physical and neurological processes between botanicals and the human ...
Breaking Medicine News(10 mins):Health News:AngelWeddingDress Has Recently Released Its Collection Of 2015 Maternity Wedding Dresses 2Health News:Commercial Auto Insurance Provides Several Important Features! 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 3Health News:EBSCO Expands Partnership with the American Medical Association 2Health News:EBSCO Expands Partnership with the American Medical Association 3Health News:EBSCO Expands Partnership with the American Medical Association 4Health News:Wicked Plants are taking over the Science Museum of Virginia 2
... of the Johns Hopkins Children,s Center and Scott Sicherer of ... caution when ordering allergy tests and to avoid making a ... article, published in the January issue of Pediatrics , ... tool in recent years, and skin-prick testing, an older weapon ...
... Doheny HealthDay Reporter , FRIDAY, Dec. 23 (HealthDay ... imaging tests between diagnosis and surgery than they did in ... -- breast ultrasounds, MRIs and mammograms -- help doctors determine ... hassles and expense of care, the study says. ...
... News) -- Reindeer have lots to do this time of ... sleighs -- but despite all their frenzied activity they manage ... overheated, researchers have found. Now, Norwegian scientists have gained ... of reindeer as they exercised on solid ground. In ...
... 23 (HealthDay News) -- Obese people who have had surgery to ... of the disease or die from cancer within five years as ... the study, published in the Dec. 1 issue of the ... Rochester, Minn., suggested their findings could change the way some doctors ...
... FRIDAY, Dec. 23 (HealthDay News) -- The holiday season can ... take steps to ensure they stay healthy through this often ... is a cancer survivor and their ranks are growing. Many ... disease and its treatment, experts at the Fred Hutchinson ...
... , FRIDAY, Dec. 23 (HealthDay News) -- Parents of ... lifestyle changes that will benefits their kids, health, a ... efforts to combat the childhood obesity epidemic among Hispanic ... United States, said the researchers at University of Texas ...
Cached Medicine News:Health News:Memo to pediatricians: Allergy tests are no magic bullets for diagnosis 2Health News:Memo to pediatricians: Allergy tests are no magic bullets for diagnosis 3Health News:Breast Cancer Patients Face More Imaging Tests Today 2Health News:Breast Cancer Patients Face More Imaging Tests Today 3Health News:Study Shows How Busy Reindeer Keep Their Cool 2Health News:Obesity Linked to Higher Esophageal Cancer Death Rates 2Health News:Cancer Survivors Should Take Steps to Keep Healthy During Holidays 2Health News:Parents May Hold Key to Healthy Weight in Hispanic Kids 2
(Date:1/22/2015)... SAN DIEGO, Jan. 22, 2015  ResMed Inc. (NYSE: ... 31, 2014. Revenue for the quarter was $423.0 million, a ... 2013 (a 14 percent increase on a constant currency basis). ... compared to the quarter ended December 31, 2013. Diluted earnings ...
(Date:1/22/2015)... , Jan. 22, 2015  Profil Institute for Clinical Research, ... and obesity, announced today a new textbook,  Translational Research ... by Springer, a leading global scientific publisher. ... illustrate techniques for use in early phase clinical studies ...
(Date:1/22/2015)... Jan. 22, 2015 Research and Markets ( http://www.researchandmarkets.com/research/w25xpc/allergy ... Market by Allergen Source, Product & by End User - ... The global allergy diagnostics market is valued at ... a CAGR of 12.67%, to reach $2,230.72 million by 2019. ...
Breaking Medicine Technology:ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 2ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 3ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 4ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 5ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 6ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 7ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 8ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 9ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 10ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 11New Textbook "Translational Research Methods for Diabetes, Obesity and Cardiometabolic Drug Development" Provides Critical Review Of Current And Emerging Clinical Investigation Methods 2New Textbook "Translational Research Methods for Diabetes, Obesity and Cardiometabolic Drug Development" Provides Critical Review Of Current And Emerging Clinical Investigation Methods 3Global Allergy Diagnostics (Immunoassay Analyzer, Luminometer, Assay Kit, Consumables) Market - Forecast to 2019 2Global Allergy Diagnostics (Immunoassay Analyzer, Luminometer, Assay Kit, Consumables) Market - Forecast to 2019 3
... , June 25 DeviceSpace is putting the ... , , ... diagnostics sectors launched the 2010 U.S. Device™ Hotbed Campaign this ... the United States . Each company participant,s brand is added to an ...
... Patient Safety Technologies, Inc. (OTC Bulletin Board: PSTX) (the "Company") ... placement financing.  The new capital will primarily be used to fund ... , , ... Stewart has been appointed as President, Chief Executive Officer and ...
Cached Medicine Technology:DeviceSpace Showcases Medical Device and Diagnostics Companies 2Patient Safety Technologies Completes $6.0 Million Equity Financing 2Patient Safety Technologies Completes $6.0 Million Equity Financing 3
Assay for Anti-HTLV-I and Anti-HTLV-II...
... assays for the blood screening market. We have ... in contract funding from the National Heart, Lung, ... develop the Procleix WNV Assay. This assay was ... under an Investigational New Drug Application (IND) on ...
Test for Anti-HBc for use on the Abbott Prism...
... BenchMark XT® the only fully automated ... you need to expand your test ... your slide turnaround time. All with ... how to use the BenchMark XT® ...
Medicine Products: