Navigation Links
FDA Warns of Codeine Risk for Some Nursing Mothers
Date:8/18/2007

Some women metabolize the drug quickly, raising chance of morphine overdose for baby

FRIDAY, Aug. 17 (HealthDay News) -- Nursing mothers who use medicines containing codeine and metabolize the drug quickly may be putting their baby at risk of a morphine overdose, U.S. health officials said Friday.

The U.S. Food and Drug Administration's warning was prompted by a report of the death of a 13-day-old breast-fed infant who died from morphine overdose. In that case, researchers found abnormally high morphine levels in the milk of the mother, who had been taking codeine to treat pain from an episiotomy. A genetic test found that the mother was an "ultra-rapid metabolizer" of codeine.

"Infants of nursing mothers who are taking codeine can have an increased risk of morphine overdose if the mother is an ultra-rapid metabolizer of codeine," Dr. Sandra Kweder, deputy director of the FDA's Office of New Drugs at the Center for Drug Evaluation and Research, said during a teleconference.

These women are genetically predisposed to metabolize codeine more rapidly and completely than other people, Kweder said. The pain-relieving effect of codeine occurs as some of it is metabolized into morphine, she explained.

Codeine is found in prescription and non-prescription medicines and used to relieve pain or treat cough. "Its use to manage pain after delivery is very common," Kweder said.

Ultra-rapid metabolizers of codeine are likely to have higher levels of morphine in their blood after taking usual doses of the drug, Kweder said. "Nursing mothers who are ultra-rapid metabolizers may also have higher morphine levels in their breast milk," she said. "These higher levels of morphine can affect the baby and lead to very severe, even life-threatening side effects in nursing babies."

Kweder advised doctors who prescribe codeine to nursing mothers to prescribe the lowest dose for the shortest amount of time.
'/>"/>


Copyright©2007 ScoutNews,LLC.

Page: 1 2 3

Related medicine news :

1. International community warns India on HIV situation
2. Thakur warns doctors
3. Paracetamol May Cause Live Damage Warns Consumer Education and Research Centre
4. Study Warns About The Use Of Popular Asthma Drug To Stop Childrens Coughs
5. Indian Government warns Gujarat regarding possibility of bird flu
6. ADB Report Warns of Bird-Flu Catastrophe
7. FDA Warns Against Birth-Control Patch
8. Charlotte Church Warns kiss n tell girls not to flirt with Henson
9. UK Committee Warns on Food Shortages Due to Flu Epidemic
10. NHS Audit Commission Warns Possible Financial Collapse In Sussex And Surrey
11. Russia warns against travel to Turkey, Iran closes border
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/30/2014)... By Randy Dotinga ... -- About one in five patients operated on for broken ... after surgery, a new study finds. Less-educated patients ... times more likely to be "doctor shoppers," said study lead ... Lexington, Ky. Overall, he said, the study suggests that doctors ...
(Date:8/30/2014)... (PRWEB) August 30, 2014 Hastings and ... injury attorneys located throughout Arizona is pleased to report ... is one specific example among many cases where Hastings ... are able to retain a greater portion of their ... case that providing a positive solution for Arizona car ...
(Date:8/30/2014)... medication commonly used to treat gout, before and ... potential complications from this type of surgery, but ... effects, according to a study published by ... online to coincide with its presentation at the ... after cardiac surgery include postpericardiotomy syndrome (the occurrence ...
(Date:8/30/2014)... "My niece developed a nighttime fever, and I ... fever might get worse," said an inventor from Montgomery, ... how she was doing, I developed this monitoring system." ... a child's temperature. The unit instantly alerts parents if ... medical care can be given, which is designed to ...
(Date:8/30/2014)... 2014 Bringing forth the great opportunities, ... announces the Labor Day discount on all SEO services. ... the complete services related to internet marketing. Their dedicated ... and others do have a deep understanding for their ... their work and since the inception, they have worked ...
Breaking Medicine News(10 mins):Health News:'Doctor-Shopping' for Painkillers Common After Broken-Bone Surgery, Study Finds 2Health News:'Doctor-Shopping' for Painkillers Common After Broken-Bone Surgery, Study Finds 3Health News:Hastings and Hastings Is Pleased To Report Having Saved A Client $67,100 On A Settlement Of $610,000 2Health News:Medication shows mixed results in reducing complications from cardiac surgery 2Health News:Profit By Search Announces Labor Day Discount on SEO Services 2
... Wired for Health Care Quality Act, Would Save Thousands ... CEOs representing,America,s top companies joined forces Wednesday, April 2, ... of the "Wired for Health Care,Quality Act," a measure ... care sector., To view the Multimedia News Release, ...
... and Allergy Foundation of America To ... Combat Allergens in the Bedroom, CINCINNATI, April ... and Allergy Foundation of America,(AAFA) to educate consumers about combating indoor ... of their lives: the bedroom., "Many people overlook the bedroom ...
... CHICAGO, April 10 Disappointment is a common theme,amongst web ... changing expectations., Businesses new to the web tend to ... web presence. Now!" We want something we can point to,that ... usually followed by weeks -- more often months --,of struggling ...
... Mass. (April 10, 2008)Researchers at Harvard Pilgrim Health Care, ... of Public Health have created and tested a set ... help clinicians detect contagious illness and automatically report them ... Electronic Medical Record Support for Public Health, or ESP, ...
... Safeguard Sight, Promote Healthy Vision ... for Children and Expand Access to Care, WASHINGTON, ... providing important leadership on health care,policy issues by doctors of ... American Optometric Association (AOA).,Optometrists in West Virginia and the AOA ...
... to 12 years off biological age , , WEDNESDAY, April 9 ... delay biological aging by up to 12 years, a new ... improve the body,s oxygen consumption and its use in generating ... begins in middle age, decreasing about 5 ml/ (kg. min) ...
Cached Medicine News:Health News:Video: Senators and CEOs Urge Passage of Health IT Bill Now 2Health News:Video: Senators and CEOs Urge Passage of Health IT Bill Now 3Health News:Leave Bedroom Allergens High and Dry This Spring! 2Health News:Leave Bedroom Allergens High and Dry This Spring! 3Health News:So ... You Went and Got a Pretty Web Site. 2Health News:Researchers pilot new electronic system for infectious illness 2Health News:Sen. Robert Byrd Receives AOA Health Care Leadership Award 2Health News:Aerobic Exercise Keeps You Young 2
(Date:8/29/2014)... Calif. , Aug. 29, 2014  Pacific Medical ... its new website design . The main website, ... that showcases the company,s new services and content relevant ... implementing a new streamlined design, viewers can now better ... for health care practices and create a more visible ...
(Date:8/29/2014)... Pixcelldata, the innovative Irish developer ... a major new deal with Dutch based eX-Path, global ... Dr. Marius Nap . The announcement ... of Pathology which is taking placing between August 30th ... London where Pixcelldata will demonstrate its innovative ...
(Date:8/29/2014)... , August 29, 2014 ... to participate in the inaugural Tweetchat taking place ... CPhI Worldwide , organised by UBM Live ... 2014. #CPhIChat is a first of its kind ... working across the supply chain, aimed to stimulate ...
Breaking Medicine Technology:PMDS Announces New Website 2Pixcelldata Announces New Deal with Dutch Tele-Pathology Specialists eX-Path Ahead of ECP 2014 2CPhI Worldwide to Host #CPhIChat Provoking Debate on the Future of Pharma 2CPhI Worldwide to Host #CPhIChat Provoking Debate on the Future of Pharma 3
... SHANGHAI , Aug. 3 /PRNewswire-Asia/ -- Sangon ... company, and Bio Basic Inc. (BBI), a Toronto ... completion of,a $10 million round of funding ... scale research & development, marketing and sales of its ...
... Aug. 3 /PRNewswire-Asia-FirstCall/ -- Concord Medical Services,Holdings Limited ... of the largest,network of radiotherapy and diagnostic imaging centers in ... for the second,quarter ended June 30, 2010 , before ... Medical,s management will hold an earnings conference call at ...
Cached Medicine Technology:Sangon & Bio Basic Inc. Closes $10 Million Round of Investment by Qiming Ventures 2Sangon & Bio Basic Inc. Closes $10 Million Round of Investment by Qiming Ventures 3Concord Medical to Report Second Quarter 2010 Financial Results on Wednesday, August 18, 2010 2Concord Medical to Report Second Quarter 2010 Financial Results on Wednesday, August 18, 2010 3
... a hot air drying device for polyacrylamide and ... cellophane support for easy viewing. The assembly table ... surface for the drying frame. The dryer holds ... 115 V, 60 Hz system includes a gel ...
... The PRO6000 power supply ... Thermo's power supply product offering. ... proteomic and genomic electrophoresis. This ... to proteomic applications such as ...
The 570-90 is capable of producing up to 500 volts or 2,500 milliamps. It is an excellent choice for running all types of electroblotting applications. Also ideal for PAGE, SDS-PAGE, and DNA or RNA s...
... techniques such as submarine electrophoresis and SDS-PAGE, ... the Series 90 Programmable Power Supplies will ... Programmable Power Supplies are available in four ... All models operate in constant voltage, current ...
Medicine Products: