Navigation Links
FDA Tells Patients to Stick With Diabetes Drug Linked to Cancer

There's no conclusive evidence that Lantus causes malignancy, agency says,,,,

WEDNESDAY, July 1 (HealthDay News) -- Despite recent studies suggesting that the injected diabetes drug Lantus (insulin glargine) might boost cancer risk, the U.S. Food and Drug Administration on Wednesday urged patients who are on the medication to continue using it.

Three of four studies published last Friday in Diabetologia showed a potential link between Lantus -- an insulin analogue made by French drug company Sanofi-aventis -- and increased risks for various tumor types.

But, "the duration of patient follow-up in all four studies was shorter than what is generally considered necessary to evaluate for cancer risk from drug exposure," the FDA said in its first comment on the issue. "Further, inconsistencies in findings within and across individual studies raise concerns as to whether an association between the use of insulin glargine and cancer truly exists."

The agency also believes that differences in the various types of patients selected for each study may have swayed the results.

"Based on the currently available data, the FDA recommends that patients should not stop taking their insulin therapy without consulting a physician, since uncontrolled blood sugar levels can have both immediate and long-term serious adverse effects," the agency wrote.

A statement released Friday by the American Diabetes Association echoed the FDA's position. "For patients using glargine and considering switching to another form of insulin, the data in these studies make it unclear as to whether any one type of insulin increases the risk of cancer more than other types of insulin," the ADA said. "Patients concerned about these studies or their insulin regimen should talk to their doctor and should not stop taking their insulin on the basis of the findings reported here."

Lantus is an "analogue," or artificial version, of insulin and is used by both type 1 and type 2 diabetics to help control blood sugar over an extended period of time. It is given by injection once daily.

The FDA says it is "currently reviewing many sources of safety data for Lantus," including completed and ongoing observational and clinical trials, and may ask Sanofi to conduct further trials should they be deemed necessary.

According to the Wall Street Journal, a spokesman for Sanofi said that the company is working with the FDA on this issue and continues to stand behind the drug's safety.

In the meantime, the FDA says it "encourages both health care professionals and patients to report side effects from the use of insulin glargine to the FDA's MedWatch Adverse Event Reporting Program."

More information

Find out more about diabetes at the American Diabetes Association.

-- E.J. Mundell

SOURCES: July 1, 2009, statement, U.S. Food and Drug Administration; June 26, 2009, statement, American Diabetes Association; Wall Street Journal

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Drummer Eddie Cleland Resumes Life After Brain Surgery and Tells About it at Conference
2. Every Picture Tells A Story, Particularly for Those With Epilepsy
3. Patient Command Tells Sec. Sebelius That Existing Technology Can Make Electronic Health Records Interoperable
4. Easy-to-Use Wristband Tells You When to Apply Sunscreen - and When to Hit the Shade
5. Health Workforce Reform Fundamental to Successful Health Reform, AAHC tells Obama Administration
6. What Is It Like to Survive a Plane Crash? A Survivor of One of the Worst Small Plane Crashes Tells Her Story
7. Especially Among Children, Prevention is Key to Halting Obesity Epidemic, President of American Dietetic Association Tells Congressional Subcommittee
8. Coast IRB Tells Congressional Committee Sting Operation Was Illegal, Unnecessarily Harmful
9. Young Tells Congress Survival of Postal Service Could Depend on Passage of Relief Legislation
10. Health Reform Must Include Health Workforce, AAHC President Tells Congress
11. Is one diet as good as another? U of I study says no and tells you why
Post Your Comments:
Related Image:
FDA Tells Patients to Stick With Diabetes Drug Linked to Cancer
(Date:11/25/2015)... (PRWEB) , ... November 25, 2015 , ... “While riding ... an inventor, from Bronx, N.Y. “I thought there had to be a convenient and ... the PROTECTOR. , The PROTECTOR enables disabled individuals to safely travel during cold or ...
(Date:11/25/2015)... ... November 25, 2015 , ... "When I underwent ... bras were incredibly uncomfortable," said an inventor from Bronx, N.Y. "In order to ... the patent-pending RECOVERY BRA for added comfort and support. The bra is easier ...
(Date:11/25/2015)... ... November 25, 2015 , ... Bcureful—a ... (TSC), as well as raising public awareness of the disorder while helping to ... third donation of $35,000 to bolster progress at the Tuberous Sclerosis Complex Center ...
(Date:11/24/2015)... ... November 25, 2015 , ... Genesis Chiropractic Software helps practice ... an agreement between the practice owner and the patient that automatically manages all ... projections. Click here to learn more. , According to ...
(Date:11/24/2015)... ... November 24, 2015 , ... Young patients with a wide variety of dental ... Dr. Kedar S. Lele, who are pediatric dentists in Tucson, AZ . Unlike ... iPlus 2.0™ system causes minimal discomfort and bleeding to the patient during treatment and ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... , November 24, 2015 ... --> adds Latest Guidebook for ... of 217 pages published in November 2015 to ... online business intelligence library at . ... of the fastest growing global economies with a ...
(Date:11/24/2015)... 24, 2015  Ascendant Solutions, Inc. (Pink Sheets: ASDS ... of Directors has declared a special 1 percent stock dividend ... payable December 14, 2015, to shareholders of record December 7, ... additional shares of common stock. --> ... a strong endorsement of our confidence in Ascendant,s growth strategy ...
(Date:11/24/2015)... Nov. 24, 2015 Diplomat Pharmacy, Inc. (NYSE: DPLO) ... of Clinical Services, Education and Human Resources will be presenting ... Oncology Drugs: Health Plan Strategies for a Dynamic Market" on ... Fenrick , a consultant with the Cambridge Advisory Group, where ... The webinar will discuss the rapid growth ...
Breaking Medicine Technology: