Navigation Links
FDA Panel Weighs Safety of Anemia Drugs for Cancer Patients
Date:3/13/2008

Growing body of evidence suggests the medications speed tumor growth, shorten lives

THURSDAY, March 13 (HealthDay News) -- When a U.S. Food and Drug Administration advisory panel meets Thursday to weigh whether blood-boosting drugs are safe to use in cancer patients suffering from anemia, the question will not be an easy one to answer.

According to FDA briefing documents filed this week, there are now a total of eight clinical trials that suggest these widely used medications, sold as Epogen and Aranesp by Amgen Inc. and as Procrit by Johnson&Johnson, actually speed the growth of tumors and shorten the lives of cancer victims. Known as erythropoiesis-stimulating agents (ESAs), they work by stimulating red blood cell production.

"Whereas at the time of approval safety concerns were theoretical, there is now mounting evidence of documented effects on survival, tumor progression, and thrombotic events which require a re-assessment of the net benefits of this class of drugs," FDA officials stated. "Based on data provided to FDA, there is no evidence that ESAs improve quality of life or cancer outcomes."

Although Thursday's meeting is only the latest in a long string of FDA actions concerning the potential dangers of these drugs since their approval in the early 1990s, the panel will be considering the possibility of completely withdrawing approval of these medications for use in cancer patients. The panel will also look at less drastic options that include less severe restrictions for patients with certain cancers or no hope of a cure and a plan that would require cancer patients to sign consent forms before starting the anemia treatments.

This isn't the only group of patients using ESAs that concerns the FDA. In kidney patients, past research has found that if these drugs are used to raise hemoglobin levels above 12 grams per deciliter of blood, the risk of death increases.

The growing body of
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Nasdaq Hearings Panel Grants TeamStaffs Request for Continued Listing Subject to a Reverse Stock Split
2. Is Cancer Community in Alignment About Cure and Costs? NCCN Conference Panel Asks
3. CDC Panel Urges Extending Flu Vaccine Coverage for Kids
4. Key Business, Labor and Academic Experts Join Stop Obesity Alliance Panel to Present Policy Perspectives and Recommendations to Reshape The Union
5. FDA Panel OKs 3 New Flu Strains for Next Years Vaccine
6. VA Creating Advisory Panel on Rural Health
7. Penn childhood obesity researchers panelists at AAAS Town Hall Event
8. Advanced Life Sciences to Participate in Antibiotics Expert Panel at the 10th Annual BIO CEO & Investor Conference
9. Harm of Abstinence-Only Programs in U.S. and Abroad Subject of Panel Discussion at Two Maine College Campuses
10. Decongestant in OTC Cold Remedies Effective: FDA Panel
11. FDA Panel Finds OTC Cold Remedies Effective
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
FDA Panel Weighs Safety of Anemia Drugs for Cancer Patients
(Date:6/3/2015)... Foot and Ankle Specialists of ... ( Clarksville Division ) was recently presented with ... Advanced Wound Care (SAWC) and the American Podiatric Medical ... The Conference was held on April 29-May 3, ... San Antonio, TX. , Dr. Casey Friske graduated ...
(Date:6/3/2015)... Israel (PRWEB) June 03, 2015 ... emergency mass-notification, multi-channel solutions, reported of its "behind-the-scenes" ... the past few months. Since March this year, ... has been inflicting the South-American country, putting millions ... ash and gas into the atmosphere. "evigilo's technology, ...
(Date:6/2/2015)... (PRWEB) June 02, 2015 The organic ... Cotton Market Report, an annual study conducted by Textile ... sustainable textile industry. The report, released today, encompasses extensive ... on a worldwide level and also takes the opportunity ... cotton market. , The last several years ...
(Date:6/2/2015)... Salisbury, NC (PRWEB) June 02, 2015 ... by hosting its sixth annual “Thriller on the Griller” ... North Carolina and South Carolina locations. Each event will ... nonprofit dedicated to restoring a sense of self, restoring ... members and our military families. , Through these ...
(Date:6/2/2015)... On Wednesday, May 27, 2015, professional driver, Brian ... speed of 207.9 mph. In the process, Hennessey’s potent ... 200 mph mark. Jay Leno was on hand to ... Jay Leno’s Garage, which will air on CNBC later this ... high speed oval at the Continental Tire Proving Grounds located ...
Breaking Medicine News(10 mins):Health News:Foot and Ankle Specialists of the Mid-Atlantic, LLC Receives Award at the Spring 2015 Symposium of Advanced Wound Care Conference 2Health News:Thousands of Lives Saved, Millions Protected in Chile 2Health News:Organic Cotton Market Sees 10% Growth Following Three Years of Decline 2Health News:Organic Cotton Market Sees 10% Growth Following Three Years of Decline 3Health News:Organic Cotton Market Sees 10% Growth Following Three Years of Decline 4Health News:Organic Cotton Market Sees 10% Growth Following Three Years of Decline 5Health News:Food Lion to Launch “Thriller on the Griller” Events to Benefit Military Families through Hope For The Warriors® 2Health News:Food Lion to Launch “Thriller on the Griller” Events to Benefit Military Families through Hope For The Warriors® 3Health News:774 HP Hennessey Mustang Tested to 207.9 mph 2
... WEDNESDAY, Nov. 16 (HealthDay News) -- A new study offers ... heart. The research found that unsaturated fats from foods ... ability to use insulin. Reduced insulin action can lead to ... Researchers examined how three different types of balanced diets consumed ...
... new study that takes a complete snapshot of adolescent cardiovascular ... teens who are likely to die of heart disease at ... research. "We are all born with ideal ... loss of that health in youth," said Donald Lloyd-Jones, M.D., ...
... of Medicine and Kyushu University Medical School say a novel ... cell-killing drugs prompts a wide variety of cancer cell types ... death. The findings are reported online in the journal ... is to stop the growth of cancerous cells while doing ...
... John DeLuca, PhD, Vice President for Research at Kessler ... technique for cognitive rehabilitation in people with multiple sclerosis ... of the Neuropsychology & Neuroscience Laboratory at Kessler Foundation. ... made on October 21, 2011 in Amsterdam at the ...
... Like a gardener who stakes some plants and weeds ... synapses, while pruning out redundant or unneeded synapses. Researchers ... Zhang, Ph.D., have discovered a factor in synapse-building, also ... of each other. Mammals are born with functioning ...
... Albert Einstein College of Medicine of Yeshiva University ... system to obtain the energy they need to keep dividing. ... researchers used genetic manipulation to turn off this recycling system ... and metastasis (cancer spread). The findings were published in ...
Cached Medicine News:Health News:Even Without Weight Loss, Mediterranean Diet Helps Heart: Study 2Health News:Today's teens will die younger of heart disease 2Health News:Today's teens will die younger of heart disease 3Health News:New drug combo targets multiple cancers 2Health News:Jackson Laboratory researchers uncover steps in synapse building, pruning 2Health News:Cancer's sweet tooth may be its weak link 2
(Date:6/2/2015)...  Endo International plc (NASDAQ: ENDP ) (TSX: ... has commenced an underwritten public offering of $1.75 billion ... the offering are to be sold by Endo. ... underwriters of the Offering an option, exercisable for a ... final prospectus supplement, to purchase an additional $262.5 million ...
(Date:6/2/2015)... Minn., June 2, 2015  MGC Diagnostics Corporation ... company, today reported financial results for the second ... 2015 second quarter domestic equipment, supplies and accessories ... flat at $4.2 million.  During the quarter, competitive ... revenue, compared to 12 accounts, or $850,000 in ...
(Date:6/2/2015)... , June 2, 2015   PDI ... solutions, today announced a series of corporate commitments ... strategies to reduce the threat of antimicrobial-resistant microorganisms ... US Centers for Disease Control and Prevention (CDC) ... Strategy to Combat Antibiotic-Resistant Bacteria. Along ...
Breaking Medicine Technology:Endo International plc Announces Proposed Public Offering of $1.75 Billion of Ordinary Shares 2Endo International plc Announces Proposed Public Offering of $1.75 Billion of Ordinary Shares 3Endo International plc Announces Proposed Public Offering of $1.75 Billion of Ordinary Shares 4MGC Diagnostics Corporation Reports Fiscal 2015 Second Quarter Results 2MGC Diagnostics Corporation Reports Fiscal 2015 Second Quarter Results 3MGC Diagnostics Corporation Reports Fiscal 2015 Second Quarter Results 4MGC Diagnostics Corporation Reports Fiscal 2015 Second Quarter Results 5MGC Diagnostics Corporation Reports Fiscal 2015 Second Quarter Results 6MGC Diagnostics Corporation Reports Fiscal 2015 Second Quarter Results 7MGC Diagnostics Corporation Reports Fiscal 2015 Second Quarter Results 8MGC Diagnostics Corporation Reports Fiscal 2015 Second Quarter Results 9MGC Diagnostics Corporation Reports Fiscal 2015 Second Quarter Results 10MGC Diagnostics Corporation Reports Fiscal 2015 Second Quarter Results 11MGC Diagnostics Corporation Reports Fiscal 2015 Second Quarter Results 12MGC Diagnostics Corporation Reports Fiscal 2015 Second Quarter Results 13MGC Diagnostics Corporation Reports Fiscal 2015 Second Quarter Results 14PDI Partners with White House and Centers for Disease Control and Prevention (CDC) to Combat Antimicrobial Resistance 2
... N.Y., Nov. 10, 2011 Sanofi (EURONEXT: SAN ... Pharmaceuticals, Inc. (NASDAQ: REGN ) today ... study program in which patients with elevated low-density ... REGN727/SAR236553 is a novel, high-affinity, subcutaneously administered, ...
... 2011 Arena Pharmaceuticals, Inc. (NASDAQ: ARNA ... ended September 30, 2011. "We are focused ... lorcaserin complete response letter around year-end and filing the ... in the first half of next year," stated Jack ...
Cached Medicine Technology:Sanofi and Regeneron Report Positive Preliminary Phase 2 Program Results for Anti-PCSK9 Antibody in Hypercholesterolemia 2Sanofi and Regeneron Report Positive Preliminary Phase 2 Program Results for Anti-PCSK9 Antibody in Hypercholesterolemia 3Sanofi and Regeneron Report Positive Preliminary Phase 2 Program Results for Anti-PCSK9 Antibody in Hypercholesterolemia 4Sanofi and Regeneron Report Positive Preliminary Phase 2 Program Results for Anti-PCSK9 Antibody in Hypercholesterolemia 5Sanofi and Regeneron Report Positive Preliminary Phase 2 Program Results for Anti-PCSK9 Antibody in Hypercholesterolemia 6Sanofi and Regeneron Report Positive Preliminary Phase 2 Program Results for Anti-PCSK9 Antibody in Hypercholesterolemia 7Sanofi and Regeneron Report Positive Preliminary Phase 2 Program Results for Anti-PCSK9 Antibody in Hypercholesterolemia 8Sanofi and Regeneron Report Positive Preliminary Phase 2 Program Results for Anti-PCSK9 Antibody in Hypercholesterolemia 9Arena Pharmaceuticals Announces Third Quarter 2011 Financial Results 2Arena Pharmaceuticals Announces Third Quarter 2011 Financial Results 3Arena Pharmaceuticals Announces Third Quarter 2011 Financial Results 4Arena Pharmaceuticals Announces Third Quarter 2011 Financial Results 5Arena Pharmaceuticals Announces Third Quarter 2011 Financial Results 6Arena Pharmaceuticals Announces Third Quarter 2011 Financial Results 7Arena Pharmaceuticals Announces Third Quarter 2011 Financial Results 8
... Built on the market leading optical performance ... has been optimized for even better views ... system, including a new XHL Xenon Halogen ... cornea and clear, high resolution images of ...
... 2.2 Fr Sur-Catch NT stone retrieval basket raises ... Its unique paired wire design and multi-sizing ... the needs of each patient and procedure. ... for use with the DURTM-8 Elite Ureteroscope and ...
The Surgiflex WAVE XP couples the state-of-the-art Surgiflex WAVE Probe with the convenience of a truly portable battery-powered pump....
... is a minimally invasive, highly effective surgical ... incontinence. GYNECARE TVT is positioned close to ... and when needed, TVT provides tension-free support ... The procedure takes approximately 20 to 30 ...
Medicine Products: