Navigation Links
FDA OKs Expanded Use of Prostate Cancer Drug
Date:12/10/2012

MONDAY, Dec. 10 (HealthDay News) -- The approved use of the drug Zytiga has been expanded to include treatment of men with late-stage, hormone therapy-resistant prostate cancer before they undergo chemotherapy, the U.S. Food and Drug Administration announced Monday.

Zytiga was initially approved in April 2011 for treatment of prostate cancer patients whose disease had progressed after treatment with the chemotherapy drug docetaxel.

The drug decreases production of the male sex hormone testosterone. In prostate cancer, testosterone stimulates prostate tumors to grow. Drugs or surgery are used to reduce testosterone production or to block the hormone's effects.

However, some men have what's called "castration-resistant" or hormone therapy-resistant prostate cancer, which means that prostate cancer cells continue to grow even with low levels of testosterone, the FDA explained in a news release.

The expanded approval is based on a study of 1,088 men with late-stage, hormone therapy-resistant prostate cancer who took either Zytiga (abiraterone acetate) or an inactive placebo in combination with another drug called prednisone.

Median overall survival was just over 35 months for patients who took Zytiga and about 30 months for those who took the placebo, the FDA noted.

The most common side effects among patients taking Zytiga included fatigue, joint discomfort, swelling caused by fluid retention, hot flush, diarrhea, vomiting, cough, high blood pressure, shortness of breath, urinary tract infection and bruising.

This expanded approval of Zytiga was made under the FDA's priority review program, which offers an accelerated six-month review for drugs that may offer major advances in treatment or provide a treatment when no adequate therapy exists.

"Today's approval demonstrates the benefit of further evaluating a drug in an earlier disease setting and provides patients and health care providers the
'/>"/>

Copyright©2012 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Prostate cancer now detectable by imaging-guided biopsy
2. Targeted prostate biopsy has potential to improve diagnosis of prostate cancer
3. The Project for Natural Health Choices Inc. Issues an Advisory for Men to Consume Flavonoids in their Diet to Protect Against Prostate Cancer
4. Targeted Prostate Cancer Biopsies Might Improve Care: Study
5. Longer life expectancy, aging population necessitate new strategies for prostate cancer care
6. Drug shows promise in prostate cancer spread to bone
7. Clinical trial at GHSU Cancer Center targets advanced prostate cancer
8. COUP-TFII sparks prostate cancer progression
9. UAlberta prostate cancer researcher and team developing homing beacon drugs to target cancer cells
10. Prostate Cancer Websites Often Hard to Understand: Study
11. Mayo Clinic gets FDA approval for new imaging agent for recurrent prostate cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/7/2015)... (PRWEB) , ... July 07, ... ... Refining convenience stores throughout the Southwest, including Giant, Mustang, Sun Dial and ... mobile program, surpassing their original 2015 fundraising goal by nearly $100,000, to ...
(Date:7/7/2015)... ... July 07, 2015 , ... A ... facial rejuvenation that have emerged about Hillary Clinton. Two plastic surgeons consulted by ... more youthful than she has in some time and speculate that she might ...
(Date:7/7/2015)... ... ... Quadrino Law Group is pleased to announce the relocation of the firm's headquarters to ... is a state of the art building, located with easy access to New York ... said, "We are pleased to service our clients from such a premier location and ...
(Date:7/7/2015)... , ... July 07, 2015 , ... Safe Catch is ... single fish for mercury. Albertsons, Gelson’s Markets, New Leaf Community Markets, Sprouts Farmers Market ... , “We developed the technology to test every fish for mercury,” said Safe Catch ...
(Date:7/7/2015)... ... July 07, 2015 , ... Parents and guardians of teenagers or young ... an open-ended holistic treatment center for drug and alcohol abuse located in Southwest Michigan. ... Research has shown a significant increase in the “club drug” use among high school ...
Breaking Medicine News(10 mins):Health News:Western Refining Raises $524,286 to Help Send Kids with Neuromuscular Disease to MDA Summer Camp 2Health News:Western Refining Raises $524,286 to Help Send Kids with Neuromuscular Disease to MDA Summer Camp 3Health News:Recent Article on Hillary Clinton Plastic Surgery Speculation Illuminates the Reasons Many Professionals Explore Facial Rejuvenation, says Dr. J 2Health News:Recent Article on Hillary Clinton Plastic Surgery Speculation Illuminates the Reasons Many Professionals Explore Facial Rejuvenation, says Dr. J 3Health News:Safe Catch Launches Tuna with Lowest Mercury Limit of Any Brand 2Health News:A Forever Recovery Releases New Information on “Club Drugs” and Tips for Parents of Teens and Young Adults 2
... Britons are packed with dust mites, fungus and skin scales.// ... to contain up to 20,000 live house dust mites in addition ... unwashed duvet revealed over an ounce and a half of debris ... addition it was found that more than four in ten people ...
... in Melbourne Australia have performed the first incompatible blood ... Royal Melbourne hospital have performed a kidney transplant despite ... was explained that Davorin Gelemanovic, 24, who is of ... from his father, who has type A blood. Mr ...
... Tata group, the Essar group and the Jindal group ... that would ensure medicare for people leaving Below Poverty ... first public-private partnership, the Sarva Swasthya Mission trust is ... major corporate groups, an official release said here today ...
... well as a good balanced diet can avert strokes in ... 1993 with over 37,600 women as participants//. ,All ... rated on a "health index score." The scores ranged from ... the woman. ,The women were followed for a ...
... of India have accorded sanction to the Karnataka government to ... from this academic year, the state assembly was informed today. ... in Belgaum and Mandya, Medical Education Minister V S Acharya ... MCI has approved an intake of 100 students in each ...
... The death toll in Dooars and Terai region of North ... and a half months till yesterday. // ,Chief ... malaria deaths were reported in Dooars region of Jalpaiguri district, ... days in the area., ,In the Terai region at ...
Cached Medicine News:Health News:Dust mites use Duvets as their Haven 2
(Date:7/7/2015)... , July 7, 2015  Dedicated to promoting ... Leonard,s® Healthcare Corp. took the purple pledge in ... is Alzheimer,s & Brain-Awareness Month, a time to shine ... the world and all the people in our community ... those struggling with the disease, and helps mobilize friends, ...
(Date:7/7/2015)... BANGALORE , July 7, 2015 /PRNewswire/ ... provider of innovative clinical trial data management solutions, has ... Reports) recent publication named " EDC and eCOA / ... ISR Reports is one of the leading providers of ... report evaluated 22 EDC and eCOA / ePRO tools ...
(Date:7/7/2015)... July 7, 2015   Bionik Laboratories Corp. ... company with a core focus in robotic exoskeleton ... the "Company"), announced today that it has completed ... units consisting of its common stock and warrants ... in a private placement transaction.  This equity financing ...
Breaking Medicine Technology:Purple for a Purpose: Supporting Alzheimer's & Brain-Awareness Month 2Acceliant Ranked Highest in 'Overall Satisfaction' Amongst EDC Providers in ISR Reports' Recent Research 2Acceliant Ranked Highest in 'Overall Satisfaction' Amongst EDC Providers in ISR Reports' Recent Research 3Bionik Laboratories Completes US$13.1 Million Private Placement 2Bionik Laboratories Completes US$13.1 Million Private Placement 3
... , , , ROCKVILLE, Md., ... of getting breast cancer, but each drug carries distinct potential harms ... for Healthcare Research and Quality. , , Drugs ... women with a family history of breast cancer or other risk ...
... , HONG KONG, Sept. 15 ... pro-healing stent, OrbusNeich,s Genous Bio-engineered R stent, and preclinical data ... week at the Transcatheter Cardiovascular Therapeutics symposium, TCT 2009, in ... M.D., Ph.D., of the Academic Medical Center in Amsterdam will ...
Cached Medicine Technology:Medications Effective in Reducing Risk of Breast Cancer But Increase Risk of Adverse Effects, New Report Says 2Medications Effective in Reducing Risk of Breast Cancer But Increase Risk of Adverse Effects, New Report Says 3Data From Multiple Clinical Trials of OrbusNeich's Genous(TM) Bio-engineered R stent(TM) to be Presented at TCT 2009 2Data From Multiple Clinical Trials of OrbusNeich's Genous(TM) Bio-engineered R stent(TM) to be Presented at TCT 2009 3
... Re-insulation capabilities that extend the life of ... bring them back to life, expertise you ... trademark. Our maintenance capabilities always help you ... Economical and fast, not only do we ...
... know their instruments will consistently perform correctly. ... Instrument for instrument repair than any other ... carbide inserts and all repairs are micro-inspected ... enjoy 24-hour turnaround from our repair center ...
... fiber and video scopes including bronchoscopes, cystoscopes, ... OR and endoscopy. Quality is of utmost ... the standards of the OEM. We back ... defects in materials and workmanship. Quotes are ...
Inquire...
Medicine Products: