Navigation Links
FDA OKs Expanded Use of Prostate Cancer Drug
Date:12/10/2012

MONDAY, Dec. 10 (HealthDay News) -- The approved use of the drug Zytiga has been expanded to include treatment of men with late-stage, hormone therapy-resistant prostate cancer before they undergo chemotherapy, the U.S. Food and Drug Administration announced Monday.

Zytiga was initially approved in April 2011 for treatment of prostate cancer patients whose disease had progressed after treatment with the chemotherapy drug docetaxel.

The drug decreases production of the male sex hormone testosterone. In prostate cancer, testosterone stimulates prostate tumors to grow. Drugs or surgery are used to reduce testosterone production or to block the hormone's effects.

However, some men have what's called "castration-resistant" or hormone therapy-resistant prostate cancer, which means that prostate cancer cells continue to grow even with low levels of testosterone, the FDA explained in a news release.

The expanded approval is based on a study of 1,088 men with late-stage, hormone therapy-resistant prostate cancer who took either Zytiga (abiraterone acetate) or an inactive placebo in combination with another drug called prednisone.

Median overall survival was just over 35 months for patients who took Zytiga and about 30 months for those who took the placebo, the FDA noted.

The most common side effects among patients taking Zytiga included fatigue, joint discomfort, swelling caused by fluid retention, hot flush, diarrhea, vomiting, cough, high blood pressure, shortness of breath, urinary tract infection and bruising.

This expanded approval of Zytiga was made under the FDA's priority review program, which offers an accelerated six-month review for drugs that may offer major advances in treatment or provide a treatment when no adequate therapy exists.

"Today's approval demonstrates the benefit of further evaluating a drug in an earlier disease setting and provides patients and health care providers the
'/>"/>

Copyright©2012 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Prostate cancer now detectable by imaging-guided biopsy
2. Targeted prostate biopsy has potential to improve diagnosis of prostate cancer
3. The Project for Natural Health Choices Inc. Issues an Advisory for Men to Consume Flavonoids in their Diet to Protect Against Prostate Cancer
4. Targeted Prostate Cancer Biopsies Might Improve Care: Study
5. Longer life expectancy, aging population necessitate new strategies for prostate cancer care
6. Drug shows promise in prostate cancer spread to bone
7. Clinical trial at GHSU Cancer Center targets advanced prostate cancer
8. COUP-TFII sparks prostate cancer progression
9. UAlberta prostate cancer researcher and team developing homing beacon drugs to target cancer cells
10. Prostate Cancer Websites Often Hard to Understand: Study
11. Mayo Clinic gets FDA approval for new imaging agent for recurrent prostate cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/13/2014)... New York (PRWEB) July 13, 2014 ... bring attention to the cancer risks associated with power ... to tell their story to federal regulators, as they ... U.S. Food & Drug Administration (FDA) advisory panel ... reports. According to the Rochester Democrat and Chronicle, ...
(Date:7/13/2014)... Athletes with a certain genetic make-up are prone ... research presented today at the American Orthopaedic Society for ... marks the first of its kind investigating a genetic ... that occur after a head injury. , “We ... (GT)n genotype were four times more likely to have ...
(Date:7/13/2014)... Trujillo Alto, Puerto Rico (PRWEB) July 13, 2014 ... that NBA Hall of Famer, Chris Mullin, will be ... Meeting on Saturday, July 26th in Puerto Rico. ... opportunities. Chris Mullin will participate in two exhibition basketball ... Max International, the ultimate supplier of health- and ...
(Date:7/13/2014)... Dallas, Texas (PRWEB) July 13, 2014 ... of aGVHD in the 6MM, from 8,062 diagnosed incident ... 2023, at an Annual Growth Rate (AGR) of 4.35%, ... have the highest number of diagnosed incident cases of ... whereas Spain will have the lowest number of diagnosed ...
(Date:7/13/2014)... July 13, 2014 According to the Kidney ... a step by step guide on what to do to ... and quickly. Vkool writes in its review that readers can ... eat to revitalize their kidney health. Vkool also informs in ... people reverse their damaged kidney functions naturally. The book consists ...
Breaking Medicine News(10 mins):Health News:Couple Who Brought Attention to Morcellator Cancer Risks Testify on Second Day of FDA Advisory Panel Meeting, Bernstein Liebhard LLP Reports 2Health News:Couple Who Brought Attention to Morcellator Cancer Risks Testify on Second Day of FDA Advisory Panel Meeting, Bernstein Liebhard LLP Reports 3Health News:Couple Who Brought Attention to Morcellator Cancer Risks Testify on Second Day of FDA Advisory Panel Meeting, Bernstein Liebhard LLP Reports 4Health News:Genetic Factors May Be Responsible for Slowing Concussion Recovery in Athletes 2Health News:Max International Announces NBA Dream Team Member Chris Mullin as Featured Guest of Charity Event 2Health News:Max International Announces NBA Dream Team Member Chris Mullin as Featured Guest of Charity Event 3Health News:Max International Announces NBA Dream Team Member Chris Mullin as Featured Guest of Charity Event 4Health News:Graft-Versus-Host Disease Market (GVHD) Growing at 4.35% AGR to 2023 Says a New Report Available at ReportsnReports.com 2Health News:Graft-Versus-Host Disease Market (GVHD) Growing at 4.35% AGR to 2023 Says a New Report Available at ReportsnReports.com 3Health News:Graft-Versus-Host Disease Market (GVHD) Growing at 4.35% AGR to 2023 Says a New Report Available at ReportsnReports.com 4Health News:Kidney Disease Solution Book Review Exposes Duncan Capicchiano's Newly Updated Kidney Disease Treatment Plan – Vkool.com 2Health News:Kidney Disease Solution Book Review Exposes Duncan Capicchiano's Newly Updated Kidney Disease Treatment Plan – Vkool.com 3
... float the first 'global health bonds' to raise $ 4 ... poor, and strengthen global immunization efforts.// ,The move will ... world to become part of the efforts to make healthcare ... investment. ,Giving information about the bonds that are ...
... of Washington University writes in his latest book Doctor’s ... has been a great scientist, inventor, publisher and statesman.// ... education has contributed a lot to preventive and modern ... America during the 18th Century in a period where ...
... Improvement has funded a grant of $30,000 to Medical ... Care to understand the usefulness of online information systemhas ... online information system woulc be helpulf for managing multiple ... to apply and the 20 selected for support from ...
... by Brian Carpenter, Ph.D., of the Washington University in St. ... two adult siblings with regard to their parents’ wants. // ... across. There is nothing which clearly indicates as to which ... wants. ,The children who feel that they ...
... the brain spring into action when one if faced with ... Hsu of the California Institute of Technology in Pasadena and ... betting games. As they played, the scientists watched changes in ... one game, researchers gave them the chance to guess the ...
... basic vaccines and introduce three new ones.,"We will give India ... will provide $40 million and then more than double it ... ,Addressing a press conference after the conclusion of the ... made a lot of progress in the vaccination and immunization ...
Cached Medicine News:Health News:Health bonds to immunize the poor 2Health News:Online information system for patients 2Health News:Adult Children Fail to Understand Parents Wishes 2
(Date:7/13/2014)... Auf seiner am ... veranstalteten F&E-Tagung meldete Astellas Fortschritte im ... Forschungsrahmenprogramms. Die Tagung bot Astellas die Gelegenheit, ... Programme und die Konzernstrategie des Unternehmens zu ... aktuelle Meldungen zu den Astellas-Initiativen in den ...
(Date:7/13/2014)... 13, 2014  Eli Lilly and Company (NYSE: ... its non-clinical study in genetically engineered mice examining ... beta-amyloid antibody N3pG and beta-secretase inhibitor BACE (LY2811376). ... effective in removing clumps of amyloid-beta protein in ... to lead to Alzheimer,s disease (AD) – than ...
(Date:7/11/2014)... LOS ANGELES , July 11, 2014 /PRNewswire-iReach/ ... of e-liquid, a vegetable-glycol solution for use in ... one of the active ingredients in cannabis, cannabidiol ... in personal vaporizer devices, and other vaporizer technology. ... Cannabis naturally contains 483 different compounds ...
Breaking Medicine Technology:Astellas erörtert Pipeline-Fortschritte auf F&E-Tagung 2Astellas erörtert Pipeline-Fortschritte auf F&E-Tagung 3Astellas erörtert Pipeline-Fortschritte auf F&E-Tagung 4New Data Shows Combination Therapy is More Effective than Monotherapy in Removing Beta-Amyloid Plaques from the Brains of Mice 2New Data Shows Combination Therapy is More Effective than Monotherapy in Removing Beta-Amyloid Plaques from the Brains of Mice 3VAPETEK Releases CBD-Infused eLiquid For The Consumer Market 2
Anti Gliadin IgG Enzyme Immunosay for quantitative determination of Gliadin-IgG antibodies in serum....
... the semi-quantitative determination of specific IgA autoantibodies ... of the anti-Gliadin IgA assay can be ... of diseases associated with elevated levels of ... these autoantibodies are one indicator in a ...
... kit is used for the quantitative measurement ... plasma. This Free Estriol kit is a ... and controls are incubated with Estriol enzyme ... antibody. Free Estriol in the patients serum ...
... The Urisys 1800 System is the ... daily urinalysis workload in a convenient and ... is designed for optimized work and data ... sediment terminal.Fast processing of test strips accelerates ...
Medicine Products: