Navigation Links
FDA OKs Avastin for Advanced Breast Cancer
Date:2/22/2008

Drug has significant risks, experts say

FRIDAY, Feb. 22 (HealthDay News) -- The U.S. Food and Drug Administration went against the recommendation of its own advisory panel on Friday and approved the cancer drug Avastin for women with advanced breast cancer.

The agency cleared the drug, made by Genentech and already approved for treating lung and colon cancer, based on findings that it slowed tumor growth, the Associated Press reported.

In a prepared statement issued Friday afternoon, Genentech said the drug won accelerated approval "in combination with paclitaxel chemotherapy, for the treatment of patients who have not received chemotherapy for their metastatic HER2-negative breast cancer. The approval is based on a Phase III study, called E2100, that showed that Avastin in combination with paclitaxel chemotherapy resulted in a 52 percent reduction in the risk of disease progression or death compared to those treated with paclitaxel alone and a doubling in progression-free survival."

"There is no cure for metastatic breast cancer, so it is important to control the disease as early and for as long as possible," Dr. Kathy Miller, lead investigator on the E2100 trial, said in the Genentech statement. "Now with Avastin plus paclitaxel, we can increase the time a womans cancer is kept under control, and offer a biologic option to women who previously were limited to chemotherapies alone," added Miller, an associate professor of medical oncology at Indiana University School of Medicine.

Last December, an expert panel of advisers to the FDA voted 5-4 that the drug's ability to slow down the growth of tumors did not outweigh the increased risk of blood clots and other cardiovascular troubles among users. In rare cases, patients taking Avastin with standard chemotherapy have died.

"Everybody wants to offer metastatic breast cancer patients hope, but we shouldn't offer them false hope," panel mem
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

0

GOOD

Page: 1 2 3

Related medicine news :

1. In Combination With FOLFOX4, the Effect of Erbitux and Avastin On Survival Rates Will Drive Prescription Decisions in the Treatment of Stage III Colon Cancer
2. Despite Oncologists Willingness to Prescribe Avastin for Treatment of Breast Cancer, the FDA is Likely to Rule Against the Product on February 23
3. Many More Patients Can Now Benefit from Avastins Proven Survival Benefits
4. Taxol with avastin produces noteworthy results
5. FDA Panel Says No to Avastin for Advanced Breast Cancer
6. Perot Systems and Oakwood Healthcare Deliver Advanced Technology & Revenue Cycle Solutions to Physicians
7. American Imaging Management Launches Patient Safety Program to Increase Awareness of Radiation Dose Associated with Advanced Imaging Procedures
8. Combo Treatment Best for Melanoma, Advanced Ovarian Cancer
9. Major study links insurance status to advanced stage in multiple cancers
10. Early warning: PSA testing can predict advanced prostate cancer
11. PSA testing can predict advanced prostate cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
FDA OKs Avastin for Advanced Breast Cancer
(Date:5/22/2013)... 2013 CoCENTRIX, a leading provider ... and Human Services and community providers, announced today ... selected the CoCENTRIX Coordinated Care Platform (CoCENTRIXccp) ... Health Records and coordinate care within and amongst ... CoCENTRIX is transitioning the hospitals' official records from ...
(Date:5/22/2013)... City, NJ (PRWEB) May 22, 2013 ... compliance, and management solutions for social enterprise collaboration ... LLC, a consulting firm based in Chicago, Ill. ... integrate their products and provide best-in-class solutions for ... and improve collaboration. , AvePoint’s DocAve Software ...
(Date:5/22/2013)... New York, NY (PRWEB) May 22, 2013 ... treated with insulin pump therapy have better glycemic control ... with T1D who treat their condition with insulin injections, ... and Wellness Survey (NHWS), conducted by Kantar ... Annual International Meeting for ISPOR (International Society for Pharmacoeconomics ...
(Date:5/21/2013)... CO (PRWEB) May 22, 2013 The ... is teaming up with HEALTHY DINING to help Coloradans ... , The new program is called HEALTHY DINING ... 300 locations are already participating in Colorado. Restaurants will ... kids and adults emphasizing lean protein, vegetables, fruits, whole ...
(Date:5/21/2013)... Standard advice for mattress shoppers often consists of ... industry’s less than exceptional satisfaction ratings and the increase ... Mattress Reports sets out to revise this advice in ... , This article addresses several components of the shopping ... be readily apparent to many shoppers. From prices to ...
Breaking Medicine News(10 mins):Health News:The State of Alabama Selects the CoCENTRIX Coordinated Care Platform to Facilitate Care for Its Citizens Treated in State Psychiatric Hospitals 2Health News:The State of Alabama Selects the CoCENTRIX Coordinated Care Platform to Facilitate Care for Its Citizens Treated in State Psychiatric Hospitals 3Health News:AvePoint Teams with Tahoe Partners, LLC to Enrich Microsoft SharePoint Deployments and Improve Collaboration 2Health News:AvePoint Teams with Tahoe Partners, LLC to Enrich Microsoft SharePoint Deployments and Improve Collaboration 3Health News:Insulin Pump Therapy Provides Better Glycemic Control Among Type 1 Diabetics, According to Kantar Health Research 2Health News:Insulin Pump Therapy Provides Better Glycemic Control Among Type 1 Diabetics, According to Kantar Health Research 3Health News:Colorado Takes a Huge Step toward Transforming the Family Dining Experience 2Health News:Colorado Takes a Huge Step toward Transforming the Family Dining Experience 3Health News:Choosing the Best Mattress Simplified in Consumer Mattress Reports’ Latest Article 2
... PAULO, Brazil, Aug. 27 Avon Global Ambassador,Reese ... celebrate the,success of the company,s first-ever global fundraising ... million since launching in March., Reese will ... Secretary for Women Policies, Ana Falu, UNIFEM Regional ...
... SAN MARCOS, Texas, Aug. 27 SBTI, a ... as an operating company,called SBTI Europe GmbH to ... for global services, SBTI is strengthening its position ... SBTI Europe GmbH is a wholly owned subsidiary ...
... variables to gauge in-hospital mortality after coronary intervention ... new scoring system for assessing patients, risk of ... be effective, according to Mayo Clinic researchers who ... Risk Score (MCRS) uses seven simple clinical and ...
... roundtable discussion as part of national ... Campaign for an American Solution, SALT LAKE CITY, ... small business owners at a,roundtable discussion on health care issues at ... health insurance industry,s Campaign for,an American Solution, a new national grassroots ...
... engineering professors from The University of Texas at Austin ... 2007 National Medal of Technology and Innovation laureates, the ... rare recognition of two honorees from the same institution ... were among eight national recipients announced this week. , ...
... Up For A Cure,s 2008,Concert Series will continue its ... Dave Matthews Band at Madison Square,Garden. The charity confirmed ... Roberts and will be preceded by a private VIP ... Stand Up For A Cure created the 2008 Concert,Series ...
Cached Medicine News:Health News:Reese Witherspoon Visits Brazil to Spread Message of Female Empowerment as Avon's Global Ambassador 2Health News:Sigma Breakthrough Technologies, Inc. (SBTI) Is Expanding Its Service Offering for Global Clients by Announcing the Public Listing of SBTI Europe GmbH 2Health News:Angioplasty Scoring System Predicts Risk of Death 2Health News:Health Insurance Industry Listens to Health Care Concerns of Utah Small Business Owners 2Health News:Health Insurance Industry Listens to Health Care Concerns of Utah Small Business Owners 3Health News:Presidential medal for technological breakthroughs earned by 2 chemical engineering professors 2Health News:Julia Roberts Joins Dave Matthews Band at Madison Square Garden in 'Stand Up For A Cure' 2008 Concert Series 2
(Date:5/22/2013)... VANCOUVER, British Columbia , May 22, 2013 /PRNewswire/ ... in the development of novel therapeutics to target mechanisms of ... its investigational compounds, custirsen and OGX-427, will be presented as ... Meeting of the American Society of Clinical Oncology (ASCO) in ... June 4. Despite the availability of drugs ...
(Date:5/22/2013)... Israel , May 22, 2013 ... NASDAQ: EMITF) announced today, further to the Company,s announcement ... motion with the Tel Aviv ... unsecured creditors and shareholders for the approval of the ... to a plan of arrangement (the "Arrangement") under Section ...
(Date:5/21/2013)... May 21, 2013 Concord Medical Services Holdings ... CCM ), a leading specialty hospital management solution provider ... diagnostic imaging centers in China and the parent of ... for the first quarter ended March 31, 2013 [1] ... Total net revenue, which consists of net revenues generated ...
Breaking Medicine Technology:OncoGenex Announces Multiple 'Trials in Progress' Presentations at the 2013 ASCO Annual Meeting 2OncoGenex Announces Multiple 'Trials in Progress' Presentations at the 2013 ASCO Annual Meeting 3OncoGenex Announces Multiple 'Trials in Progress' Presentations at the 2013 ASCO Annual Meeting 4OncoGenex Announces Multiple 'Trials in Progress' Presentations at the 2013 ASCO Annual Meeting 5Elbit Imaging Announces the Court Decision with Respect to Filing of Plan of Arrangement with the Israeli Court 2Elbit Imaging Announces the Court Decision with Respect to Filing of Plan of Arrangement with the Israeli Court 3Concord Medical Reports First Quarter 2013 Financial Results 2Concord Medical Reports First Quarter 2013 Financial Results 3Concord Medical Reports First Quarter 2013 Financial Results 4Concord Medical Reports First Quarter 2013 Financial Results 5Concord Medical Reports First Quarter 2013 Financial Results 6Concord Medical Reports First Quarter 2013 Financial Results 7Concord Medical Reports First Quarter 2013 Financial Results 8Concord Medical Reports First Quarter 2013 Financial Results 9Concord Medical Reports First Quarter 2013 Financial Results 10Concord Medical Reports First Quarter 2013 Financial Results 11Concord Medical Reports First Quarter 2013 Financial Results 12Concord Medical Reports First Quarter 2013 Financial Results 13
... Practice Fusion, the fastest growing Electronic Medical ... Jason Portnoy as the company,s Chief Financial Officer.  Practice ... enabling charting, scheduling, e-prescribing and lab integrations.  Portnoy joins ... his deep expertise in scaling hyper-growth companies. ...
... Echo Therapeutics, Inc. (OTC Bulletin Board: ... System as a non-invasive, wireless, transdermal continuous glucose ... for transdermal drug delivery, today announced that it ... Sullivan Technology Innovation Award in Pharmaceuticals and Biotechnology. ...
Cached Medicine Technology:Former PayPal, Palantir Executive Jason Portnoy Joins Practice Fusion as CFO 2Former PayPal, Palantir Executive Jason Portnoy Joins Practice Fusion as CFO 3Echo Therapeutics Receives Frost & Sullivan's 2011 Technology Innovation Award 2Echo Therapeutics Receives Frost & Sullivan's 2011 Technology Innovation Award 3Echo Therapeutics Receives Frost & Sullivan's 2011 Technology Innovation Award 4
... Aura's precision optics and targeting make ... care. The 16 degree cone angle, adjustable ... you to perform capsulotomies on the most ... laser design and precision optics ensure low ...
... anterior segment of the eye by a ... supplies pictures in three dimensions. The center ... because of this rotational imaging process. The ... and minute eye movements are captured and ...
... Non -Contact Specular Microscope is a ... versatility in non-contact specular microscopy. The ... Imagenet system. Dual measurement system: Corneal ... auto alignment and auto capture system. ...
Ahmed Glaucoma Valve (small size)....
Medicine Products: