Navigation Links
FDA OKs Avastin for Advanced Breast Cancer
Date:2/22/2008

Drug has significant risks, experts say

FRIDAY, Feb. 22 (HealthDay News) -- The U.S. Food and Drug Administration went against the recommendation of its own advisory panel on Friday and approved the cancer drug Avastin for women with advanced breast cancer.

The agency cleared the drug, made by Genentech and already approved for treating lung and colon cancer, based on findings that it slowed tumor growth, the Associated Press reported.

In a prepared statement issued Friday afternoon, Genentech said the drug won accelerated approval "in combination with paclitaxel chemotherapy, for the treatment of patients who have not received chemotherapy for their metastatic HER2-negative breast cancer. The approval is based on a Phase III study, called E2100, that showed that Avastin in combination with paclitaxel chemotherapy resulted in a 52 percent reduction in the risk of disease progression or death compared to those treated with paclitaxel alone and a doubling in progression-free survival."

"There is no cure for metastatic breast cancer, so it is important to control the disease as early and for as long as possible," Dr. Kathy Miller, lead investigator on the E2100 trial, said in the Genentech statement. "Now with Avastin plus paclitaxel, we can increase the time a womans cancer is kept under control, and offer a biologic option to women who previously were limited to chemotherapies alone," added Miller, an associate professor of medical oncology at Indiana University School of Medicine.

Last December, an expert panel of advisers to the FDA voted 5-4 that the drug's ability to slow down the growth of tumors did not outweigh the increased risk of blood clots and other cardiovascular troubles among users. In rare cases, patients taking Avastin with standard chemotherapy have died.

"Everybody wants to offer metastatic breast cancer patients hope, but we shouldn't offer them false hope," panel mem
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. In Combination With FOLFOX4, the Effect of Erbitux and Avastin On Survival Rates Will Drive Prescription Decisions in the Treatment of Stage III Colon Cancer
2. Despite Oncologists Willingness to Prescribe Avastin for Treatment of Breast Cancer, the FDA is Likely to Rule Against the Product on February 23
3. Many More Patients Can Now Benefit from Avastins Proven Survival Benefits
4. Taxol with avastin produces noteworthy results
5. FDA Panel Says No to Avastin for Advanced Breast Cancer
6. Perot Systems and Oakwood Healthcare Deliver Advanced Technology & Revenue Cycle Solutions to Physicians
7. American Imaging Management Launches Patient Safety Program to Increase Awareness of Radiation Dose Associated with Advanced Imaging Procedures
8. Combo Treatment Best for Melanoma, Advanced Ovarian Cancer
9. Major study links insurance status to advanced stage in multiple cancers
10. Early warning: PSA testing can predict advanced prostate cancer
11. PSA testing can predict advanced prostate cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
FDA OKs Avastin for Advanced Breast Cancer
(Date:8/30/2014)... Aliso Viejo, California (PRWEB) August 30, 2014 ... have announced the release of the TransGhost plugin from ... frightening tool that gives users the ability to tell ... Austin, CEO of Pixel Film Studios. “Users will make ... to use transition plugin.” , With TransGhost users can ...
(Date:8/30/2014)... (PRWEB) August 30, 2014 The SI ... nine mobilizations and six muscle energy techniques. Michael P. ... and demonstrates twenty-seven examination techniques for the SI Joint. ... supports Dr. Reiman's live course presentation with North American ... Applying a differential diagnosis approach to ...
(Date:8/30/2014)... (PRWEB) August 30, 2014 The KSF ... Challenge and K.Warrior Search on November 8th, 2014 at ... years, these events have introduced many notorious and notable ... Strike-Force, IWF and the UFC. , Among these ... fighters leave its doors armed with the virtues of ...
(Date:8/30/2014)... Saturday 30 August 2014: The first multidisciplinary ... with acute coronary syndromes (ACS) are published today ... paper was written jointly by the European Heart ... (ACCA) and the European Association of Percutaneous Cardiovascular ... Professor Bulent Gorenek (Turkey), chairperson of the task ...
(Date:8/30/2014)... Saturday 30 August 2014: The first recommendations ... in pulmonary embolism are published today in new ... Congress by Professor Stavros V. Konstantinides (Germany/Greece) and ... Guidelines on the diagnosis and management of acute ... Heart Journal (1) and on the ESC Website. ...
Breaking Medicine News(10 mins):Health News:Pixel Film Studios Released TransGhost Plugin for Final Cut Pro X Today 2Health News:Pixel Film Studios Released TransGhost Plugin for Final Cut Pro X Today 3Health News:North American Seminars Online PT Continuing Education Course, Examination and Treatment of the SI Joint, Receives Continuing Education Approval in NJ, CA, IL, PA, & TX 2Health News:KSF Presents US Open Challenge-K. Warrior Search, Seeking Inspirational Warrior Fighters Like Cung Le 2Health News:KSF Presents US Open Challenge-K. Warrior Search, Seeking Inspirational Warrior Fighters Like Cung Le 3Health News:KSF Presents US Open Challenge-K. Warrior Search, Seeking Inspirational Warrior Fighters Like Cung Le 4Health News:First multidisciplinary recommendations on management of arrhythmias in ACS patients 2Health News:First recommendations on all new oral anticoagulants in pulmonary embolism published 2
... April 23 (HealthDay News) -- It goes without saying that ... they can also be very expensive, an expert warns. ... a person bitten by a venomous snake, said Jill Heatley, ... in College Station. The total cost includes hospitalization, which ...
... The International and American Associations for Dental ... in children. These articles, titled "Hypoplasia-Associated Severe Early ... Page Caufield, New York University College of Dentistry) ... (lead author M.E.C. Elfrink, Academic Centre for Dentistry, ...
... destruction of the insulin-producing beta cells. Over 250,000 patients suffer ... daily insulin injections to maintain glucose metabolism. Replacement of the ... organ or isolated human beta cells is the only effective ... of organ donors this method can be offered to only ...
... St. Jude Children,s Research Hospital scientists have rewritten the ... it guards early brain cells from DNA damage. Such ... showed that cells in the developing brain require TopBP1 ... is copied prior to cell division. Investigators also reported ...
... That "brain freeze" headache you experience when eating ice cream ... change in brain blood flow, researchers report. What,s more, ... more troubling forms of headache such as migraine, the U.S. ... blood flow in 13 healthy adults as they sipped ice ...
... April 22 (HealthDay News) -- Tick season has started earlier ... gardeners and others who love the outdoors should take precautions ... People also should keep alert for symptoms of tick-borne ... tick-borne diseases such as Lyme disease, anaplasmosis and babesiosis -- ...
Cached Medicine News:Health News:Cost of Snakebite Therapy May Squeeze Victims' Wallets 2Health News:IADR/AADR publish studies on severe early childhood caries - proposes new classification 2Health News:IADR/AADR publish studies on severe early childhood caries - proposes new classification 3Health News:Xenotransplantation as a therapy for type 1 diabetes 2Health News:Protein prevents DNA damage in the developing brain and might serve as a tumor suppressor 2Health News:Protein prevents DNA damage in the developing brain and might serve as a tumor suppressor 3Health News:'Ice Cream Headaches' Might Offer Clues to Migraines 2Health News:Tick Season Starting Early This Year 2
(Date:8/29/2014)... 29, 2014  BC Technical, the nation,s leading non-OEM ... Imaging, a leader in sales, service and installation of ... BC Technical to continue to expand their resources and ... CT modalities. "We are committed to ... Alvarez , president and CEO of BC Technical. "We ...
(Date:8/29/2014)... 2014 According to a ... Extraction type (SFE, Cold Pressed, Organic Solvent, & Others), ... Food Supplements, Fragrance, & Others) - Global Trends & ... segments the Amaranth Seed Oil Market with an ... terms of value. The Amaranth Seed Oil Market ...
(Date:8/29/2014)...   Vittamed Corporation , a neurodiagnostics medical device company ... T. (Teo) Forcht Dagi , MD, DmedSc, MPH, MBA, ... " Teo Forcht Dagi is an ... and venture capital," said Remis Bistras , President and ... clinical, strategic, and entrepreneurial expertise to our Board." ...
Breaking Medicine Technology:BC Technical Acquires Polaris Medical Imaging 2Amaranth Seed Oil Market worth $700.6 Million by 2019 2Amaranth Seed Oil Market worth $700.6 Million by 2019 3Amaranth Seed Oil Market worth $700.6 Million by 2019 4Vittamed Adds Prominent Neurosurgeon and Venture Capitalist T. Forcht Dagi to Board of Directors 2
... Va., Jan. 19, 2012 Medicare officials should swiftly authorize ... a new Medicare Part D prescription drug plan if the ... for a "preferred network" plan with inadequate pharmacy access, the ... Since the start of the 2012 plan year on ...
... /PRNewswire-Asia-FirstCall/ -- Mindray Medical International Limited (NYSE: ... medical devices worldwide, today announced that it will participate ... January 23 and 26 in Dubai, United Arab Emirates. ... annual medical exhibition in the Middle East.  Last year, ...
Cached Medicine Technology:Pharmacists Ask Medicare to Help Seniors Complaining About Inadequate Pharmacy Access in Medicare Prescription Drug Plans 2Pharmacists Ask Medicare to Help Seniors Complaining About Inadequate Pharmacy Access in Medicare Prescription Drug Plans 3Mindray Medical to Exhibit at Arab Health 2012 in Dubai from January 23-26 2
... The Professional Gold Package is ... laboratory. The package includes the ... automated system, starter package accessory ... adapter, specimen mounts 1/2" head, ...
... Semi-Automatic Tissue Sectioning System has maintained the ... system. Researchers from around the globe have ... their fresh and fresh fixed tissue sectioning ... With the Vibratome Automatic Tissue Sectioning Systems, ...
... Plus Sectioning System provides a versatile means ... plant tissues. The 1000 employs a ... freezing or embedding. The creation of ... of enzyme activities, and other deleterious effects ...
... with a square vice mounting device. ... for mounting specimens and placing in ... blocks are annodized black for easy ... They are shipped three to ...
Medicine Products: