Navigation Links
FDA Gives Nod to Botox to Treat Overactive Bladder
Date:1/18/2013

FRIDAY, Jan. 18 (HealthDay News) -- The U.S. Food and Drug Administration on Friday gave its approval for the use of Botox against a form of urinary incontinence known as overactive bladder.

"Clinical studies have demonstrated Botox's ability to significantly reduce the frequency of urinary incontinence," Dr. Hylton Joffe, director of the Division of Reproductive and Urologic Products in the FDA's Center for Drug Evaluation and Research, said in an agency news release.

"Today's approval provides an important additional treatment option for patients with overactive bladder, a condition that affects an estimated 33 million men and women in the United States," he added.

Overactive bladder is a condition where the bladder contracts too frequently or without warning, causing incontinence, sudden/urgent urge to urinate and frequent urination.

However, injections of Botox (onabotulinumtoxinA) into the bladder muscle can trigger a relaxation of the bladder, boost the organ's storage capacity and make incontinence episodes less frequent, the FDA said.

Physicians inject the drug while using cytoscopy, a procedure that allows the doctor to visualize the interior of the bladder as injection occurs.

The FDA said the safety and effectiveness of Botox for this use was verified in two clinical trials involving more than 1,100 patients with overactive bladder, with patients receiving either 100 units of Botox (20 injections of 5 units each) or a placebo.

Lasting more than three months, the trials found that Botox patients experienced close to two fewer bouts of urinary incontinence a day compared to those on a placebo, had fewer urinations per day, and an average of 30 milliliters more urine expelled each day, compared to those on a placebo.

Side effects included urinary tract infections, painful urination and incomplete emptying of the bladder, the FDA said. People who already have a urinary tract infection should not take Botox for overactive bladder, and people who do take the drug should take antibiotics before, during and for a few days after the procedure, the agency added.

Botox, best known for its ability to temporarily smooth away facial lines and wrinkles, is made by Allergan Inc. of Irvine, Calif.

More information

Find out more about overactive bladder at the American Urological Association.

-- E.J. Mundell

SOURCE: Jan. 18, 2013, news release, U.S. Food and Drug Administration


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Author of the Uplifting Cancer Survival Guide, The C Card and Me, Gives Her Book Away to Millions
2. U.S. Gives States More Time to Set Up Health Insurance Exchanges
3. Wake-Up Call: Medical Malpractice Attorneys at Console & Hollawell Express Concern After Surgeon Gives Hepatitis B to Patients
4. CPS Magazine Announces a CDT Code for Resin Infiltration that Gives Dental Practices Additional Treatment and Billing Options for New Dental Material Icon by DMG America
5. Fit and Healthy with Beth gives Her Tips to Stay Stress Free this Holiday Season
6. What Causes Hot Flashes? Rat Study Gives New Clues
7. Carolina Women's Physicians Gives Key Tips for Eating Healthy During the Holiday Season
8. I Fly First Class Gives New Tips on How to Avoid Sickness and be Prepared for Your Next Trip
9. No Proof That Doping With EPO Gives Athletes an Edge: Review
10. Mitchell Vazquez Gives Away Donations to Advance Cancer Research Cause
11. Synchrotron gives insight into green energy enzymes
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
FDA Gives Nod to Botox to Treat Overactive Bladder
(Date:8/18/2017)... ... August 18, 2017 , ... Mediaplanet today announces the launch ... lifestyles and highlighting the importance of proactive eye and ear health. The campaign ... latest innovations in hearing aid technology. , In this issue, the American ...
(Date:8/18/2017)... ... 18, 2017 , ... Radabaugh & Associates, a family managed ... North-Central West Virginia, is embarking on a cooperative charity effort with the Chestnut ... The Chestnut Mountain Ranch (CMR) is a Christ-centered boarding school for young men ...
(Date:8/18/2017)... ... August 18, 2017 , ... Goss & Associates Insurance Agency, ... commercial clients in the greater Houston region, is helping locally recognized nonprofit Addi’s ... against cancer. , Founded by Tony and Amber Bender after losing their young ...
(Date:8/18/2017)... (PRWEB) , ... August 18, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The ... says will lift the veil on false teachings pertaining to the mother of the Savior ... teach, you see a far different picture of the role of this historical woman. ...
(Date:8/18/2017)... ... August 18, 2017 , ... “Our Mountains to Climb: A ... a couple that grew stronger together through the faith they shared to overcome struggles ... is the creation of published author, Barbara J. Corcoran, a retired teacher and happily ...
Breaking Medicine News(10 mins):
(Date:8/7/2017)... (NYSE: DPLO), the nation,s largest independent specialty pharmacy, announced financial ... unless otherwise noted, are to the quarter ended June 30, ... 2017 Highlights include: Revenue of $1,126 ... Total prescriptions dispensed of 220,000, compared to 241,000 ... Gross profit per prescription dispensed of $371, ...
(Date:8/4/2017)... , Aug. 3, 2017  Agragen, LLC, ... company active in the biopharmaceutical, nutraceutical, and aquacultural ... development of its lead drug candidates, AGR131.  This ... proinflammatory cytokine from the blood of patients suffering ... and inflammatory bowel disease. ...
(Date:8/2/2017)... , Aug. 2, 2017   Marshall County Hospital in Benton, Kentucky ... reduce the risk of hospital-acquired infections (HAIs). The new addition, Tru-D SmartUVC , short ... to kill deadly pathogens such as C. diff , MRSA, MERS, Ebola and more. ... Tru-D SmartUVC ... Tru-D in action in a patient room ...
Breaking Medicine Technology: