Navigation Links
FDA Clears Cellectar's IND Application for Lead Drug Candidate
Date:3/3/2009

(131)I-CLR1404 to Enter Clinical Trials

MADISON, Wis., March 3 /PRNewswire/ -- Cellectar, Inc., a privately held radiopharmaceuticals company that designs and develops products to detect, treat and monitor human cancers, today announced that the U.S. Food and Drug Administration (FDA) has cleared the Company's Investigational New Drug (IND) application for its (131)I-CLR1404 drug candidate for testing in patients with advanced solid malignancies. The company expects to begin phase I clinical studies in the second quarter of 2009.

The first phase I study will enroll up to 9 patients and will include drug dosimetry calculations and biodistribution assessments. The second phase I study will be a dose escalation study evaluating the Maximum Tolerated Dose (MTD) of (131)I-CLR1404 in patients with advanced solid malignancies; both studies will be performed at four leading U.S. medical centers.

Cellectar's President and CEO, Bill Clarke, M.D., commented, "We are extremely pleased to have received FDA clearance allowing us to advance our lead product candidate into human clinical studies. Further, we are hopeful that this novel anti-cancer compound, selectively retained by cancer cells, may provide benefit to solid tumor patients with few therapeutic options."

About (131)I-CLR1404

Cellectar's (131)I-CLR1404 is a small-molecule, phospholipid ether analog that combines lipid-like properties with a cancer therapeutic beta-emitting radioisotope. Cellectar believes that this compound will benefit individuals with cancer due to its selective retention and accumulation in malignant cells versus nonmalignant cells. Preclinical animal studies demonstrated that (131)I-CLR1404 significantly slowed the growth of malignant solid tumors and resulted in improved survival. Non-radiolabeled CLR1404 proved safe at doses greater than 1000x the anticipated human dose.

About
'/>"/>

SOURCE Cellectar, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2

Related medicine news :

1. Global Gene Map Clears New Milestone
2. FDA Clears MDN-CGS(R) Intravenous Insulin Dosing Software
3. American Medical Association Clears Path for Adenoviral Conjunctivitis - Pink Eye - Detector
4. Congress Clears the Way for National CPR and AED Awareness Week
5. FDA Clears Cellsearch(TM) Circulating Tumor Cell Test for Monitoring Metastatic Prostate Cancer Patients
6. ClearScript Offers Innovative Medication Therapy Management Program to Employee Health Plans
7. Alzheimers vaccine clears plaque but has little effect on learning and memory impairment
8. Genetic Information Nondiscrimination Act clears Senate
9. Dutch Authorize Manufacture of Vaccinogens New Cancer Vaccine; License Clears Path to European Production, Final FDA Trial
10. FDA Clears NeuroStar(R) TMS Therapy for the Treatment of Depression
11. FDA Clears the DPL (Deep Penetrating Light) Therapy System for Over-the-Counter - Home Use
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2014)... Drug and alcohol addiction is ... abuse has claimed thousands of lives throughout the region. ... hope for teenagers who are seeking to overcome their ... to provide adolescents and their parents with guidance, support ... youth rehab facility to meet their specific needs. ...
(Date:8/22/2014)... According to the market research report "Blind ... (ACC) System Market for Passenger Cars; by Geography ... by MarketsandMarkets, classifies and defines the automotive BSD ... and value. The report highlights potential growth opportunities ... review of the market drivers, restrains, growth indicators, ...
(Date:8/21/2014)... New York (PRWEB) August 22, 2014 ... for the Long Island region, proudly announces the launch ... site, focused on the West Babylon-based yoga studio’s new ... who wish to become teachers realize their dreams. , ... community and those living in the surrounding area a ...
(Date:8/21/2014)... Florida Hospital Zephyrhills is the ... the only in the Tampa Bay area to ... Olympus Endoalpha Universal Platform for surgical endoscopy. The ... specialties, and provides the hospital a standardized solution ... and patient care. Surgical endoscopy systems, through the ...
(Date:8/21/2014)... 21, 2014 August 11: – Robin ... own life by hanging, likely due to long-term depression. ... the foremost BioAcoustic Vocal Profiling investigator, appeared on the ... concerning Williams’ death; hoping to help people understand why ... to Williams’ suicide were proposed in terms of BioAcoustic ...
Breaking Medicine News(10 mins):Health News:Substance Abuse Helpline Provides Hope for Teens & Parents in Brunswick, OH 2Health News:Automotive Blind Spot Detection System Market Worth $2.8 Billion and Automotive Adaptive Cruise Control System Market Worth $6.1 Billion by 2019 – New Report 2Health News:Automotive Blind Spot Detection System Market Worth $2.8 Billion and Automotive Adaptive Cruise Control System Market Worth $6.1 Billion by 2019 – New Report 3Health News:Automotive Blind Spot Detection System Market Worth $2.8 Billion and Automotive Adaptive Cruise Control System Market Worth $6.1 Billion by 2019 – New Report 4Health News:Yoga Darshana Center Announces Launch of New Website LongIslandYogaTeacherTraining.com 2Health News:Florida Hospital Zephyrhills is Elevating Healthcare by Offering the First Olympus Fully-Integrated HD Operating Room in Pasco County 2Health News:Florida Hospital Zephyrhills is Elevating Healthcare by Offering the First Olympus Fully-Integrated HD Operating Room in Pasco County 3Health News:Robin Williams: What he could not bear to face 2Health News:Robin Williams: What he could not bear to face 3
... Dental Network of America,Inc. (DNoA), announces double digit growth ... DNoA Preferred Network -- now totaling over 120,000,dentist access points ... network growth places DNoA as the largest dental network,in terms ... as of,September 2008, powered by The Ignition Group,( http://www.theignitiongroup.net ). ...
... Premier Net-Centric Alert and Notification Technology Company today announces the ... Medical Center. , ... Washington, D.C. ... a Premier Net-Centric Alert and Notification Technology Company, today announces ...
... the Dec. 15 issue of the Journal of Clinical ... clinical picture of comorbid conditions associated with obstructive sleep apnea ... interrelationships. , Results show that the number of cases ... low during adolescence, and then rises from 25-29 years to ...
... new therapeutic target for pancreatic cancer, the most lethal ... proteins whose DNA recipe comes from gene, "Seven-In-Absentia," according ... (ASCB) 48th Annual Meeting, Dec. 13-17, 2008 in San ... fly, Drosophila melanogaster, at the Mayo Clinic College of ...
... of year, experts say , , SUNDAY, Dec. 14 (HealthDay News) ... many, it can cause depression for seniors who,ve lost loved ... some seniors, this despondency can lead to suicide, according to ... rate for Americans over the age of 65 was 14 ...
... a Sales Kaizen event to Improve Your Sales Process in a Way ... GA. A teleconference introducing the book will be held on Dec 18, ... ... 2008 -- Companies everywhere are struggling to find ways of generating more ...
Cached Medicine News:Health News:Dental Network of America Becomes Largest National Dental Network in the U.S. 2Health News:Berkshire Medical Center Selects Desktop Alert for Mass Notification Solutions 2Health News:Berkshire Medical Center Selects Desktop Alert for Mass Notification Solutions 3Health News:Berkshire Medical Center Selects Desktop Alert for Mass Notification Solutions 4Health News:Data mining of inpatient records reveals the disease pattern of obstructive sleep apnea 2Health News:Blocking molecular pathway with whimsical name possible therapeutic target for pancreatic cancer 2Health News:Helping Seniors Beat the Holiday Blues 2Health News:New Guidebook Published for Improving B2B Sales Results in 90 Days or Less Through Kaizen Events 2Health News:New Guidebook Published for Improving B2B Sales Results in 90 Days or Less Through Kaizen Events 3
(Date:8/21/2014)... 2014  ACI Clinical ( www.aciclinical.com ) announces ... Committees. Using this solution, trial sponsors ... standard costs and receive the same expertise that ... services. Leveraging a decade of DMC ... development, statistical programming and meeting facilitation), ACI analyzed ...
(Date:8/21/2014)... 2014  Armada Health Care (Armada), the nation,s ... pleased to announce an agreement with Aurora Health ... innovative specialty pharmacy patient program offerings. The new ... services to specialty patients via Armada,s proprietary ReachRx ... will use the OTM platform as its case ...
(Date:8/21/2014)... 2014  The board of directors of VirtualScopics, Inc. ... clinical trial imaging solutions, today announced that James ... effective immediately.  Mr. Groff has held the role of ... VirtualScopics in January 2006 as an accounting manager and ... "When the board of VirtualScopics asked Jim to assume ...
Breaking Medicine Technology:ACI Clinical: Innovation and Savings in Data Safety Monitoring Committees 2Aurora Health Care Partners with Armada Health Care to Deliver Added Pharmacy Capabilities to Specialty Patients 2Aurora Health Care Partners with Armada Health Care to Deliver Added Pharmacy Capabilities to Specialty Patients 3VirtualScopics, Inc. Names James Groff Chief Financial Officer 2VirtualScopics, Inc. Names James Groff Chief Financial Officer 3VirtualScopics, Inc. Names James Groff Chief Financial Officer 4
Contoured waterfall-front ergonomic seats and generous backrests with lumbar support are standard on these ergonomic chairs. • With Tubular Base....
Contoured waterfall-front ergonomic seats and generous backrests with lumbar support are standard on these ergonomic chairs. • With Tubular Base....
Contoured waterfall-front ergonomic seats and generous backrests with lumbar support are standard on these ergonomic chairs. • With Tubular Base....
Inquire...
Medicine Products: