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FDA Approves NOVO NORDISK's NovoSeven(R) RT (Coagulation Factor VIIa [Recombinant] Room Temperature Stable) for Hemophilia Patients With Inhibitors
Date:5/13/2008

ey're taking NovoSeven(R) may be at increased risk for thrombosis. Serious adverse events which may or may not have been related to the use of NovoSeven(R) occurred in 14 of the 298 patients in the initial clinical program. There have been no reports of NovoSeven(R) causing bad reactions to "analgesics" (such as pain killers), "antibiotics" (the drugs used to treat infection), or "sedatives" (sleeping pills or tranquilizers). Development of antibodies against Factor VII has been reported in Factor VII-deficient patients after treatment with NovoSeven(R). These patients had previously been treated with human plasma and/or plasma-derived Factor VII.

About Novo Nordisk

Novo Nordisk is a health care company and a world leader in diabetes care. The company has the broadest diabetes product portfolio in the industry, including the most advanced products within the area of insulin delivery systems. In addition, Novo Nordisk has a leading position within areas such as hemostasis management, growth hormone therapy, and hormone replacement therapy.

Novo Nordisk manufactures and markets pharmaceutical products and services that make a significant difference to patients, the medical profession, and society. With headquarters in Denmark, Novo Nordisk employs more than 23,600 employees in 79 countries and markets its products in 179 countries. Novo Nordisk's B shares are listed on the stock exchanges in Copenhagen and London. Its ADRs are listed on the New York Stock Exchange under the symbol 'NVO'. For more information, visit novonordisk.com.

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Sean Clements

Novo Nordisk

PH: (609) 514-8316


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