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FDA Approval of new Prostate Treatment Shows Promise of Cancer Immunotherapy
Date:4/29/2010

ient outcomes by advancing the science, development and application of biological therapy.”

The iSBTc focuses on exchanging, encouraging and promoting information about developments in biological therapies for treating cancer patients among bench scientists, researchers, clinicians and students.

“The society was founded on the belief that new biologic systemic treatments would complement traditional surgery, radiation, chemotherapy and targeted therapies and join the mainstream in the fight against cancer,” Dr. Fox says. “These recent advances in immunology and biology have opened new horizons in cancer therapy, with an upsurge in the integration of new biologic agents into clinical practice.”

Clinical trials of Provenge have demonstrated a statistically significant improvement in overall survival of men with metastatic castrate-resistant prostate cancer (CRPC). The results from a Phase 3 IMPACT study of 512 men reported that, compared with a placebo, Provenge increased three-year survival by 38 percent, and extended median survival by 4.1 months, with a 22.5 percent reduction in the risk of death. (IMPACT is an acronym for Immunotherapy for Prostate AdenoCarcinoma Treatment.)

“The approval of this treatment supports our members’ ongoing research and investigation of immunotherapy as an innovative cancer treatment vehicle,” Dr. Fox says. “This new treatment option is good news for thousands of prostate cancer patients whose cancer has been resistant to other therapies.”

According to the American Cancer Society, prostate cancer is the most common non-skin cancer among men in the United States and the third most common cancer worldwide. More than 1 million men in the United States have prostate cancer. An estimated 192,280 new cases were expected to be diagnosed in 2009, and approximately 27,360 men were expected to die that year from the disease.

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