Navigation Links
FDA Announces Safety Risk Associated with HIV Drug
Date:2/1/2010

Rare, but serious, liver disorder reported in some patients

SILVER SPRING, Md., Feb. 1 /PRNewswire-USNewswire/ -- The U.S. Food and Drug Administration today announced that non-cirrhotic portal hypertension, a rare, but serious, liver disorder, has been reported in some HIV patients taking Videx/Videx EC (didanosine).

(Logo:  http://www.newscom.com/cgi-bin/prnh/20090824/FDALOGO )

Videx is an antiretroviral medicine first approved by the FDA in 1991. Videx EC is a delayed-release version of Videx approved in 2000. Videx/Videx EC is used in combination with other antiretroviral medicines to treat HIV infection in children and adults.

During an 18-year period, 42 cases of non-cirrhotic portal hypertension were reported to the FDA's Adverse Event Reporting System for patients taking Videx/Videx EC. Four patients died from bleeding or liver failure after developing the condition.

Non-cirrhotic portal hypertension occurs when blood flow in the portal vein -- a major vein in the liver -- slows down and leads to severely enlarged veins in the esophagus. These enlarged veins, called esophageal varices, are thin and can break open, resulting in serious, and potentially fatal, bleeding.

The Videx and Videx EC product labels have been revised to help ensure that health care professionals and patients are aware of the risk and the signs and symptoms of non-cirrhotic portal hypertension.

The FDA evaluation concluded that the clinical benefits of Videx/Videx EC in certain patients with HIV continue to outweigh potential safety risks. Videx/Videx EC does not cure HIV infection, may not prevent development of HIV-related illnesses, and may not prevent the spread of HIV to other people.  

Videx/
'/>"/>

SOURCE U.S. Food and Drug Administration
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2

Related medicine news :

1. Recondo Technology Announces Omni278 UnitedHealthcare Admission Notification Service
2. Trek Bicycle Announces Title Sponsorship of 2010 Dirt Series
3. Sinovac Announces Exercise of Over-Allotment Option
4. Rapport International Announces Partnership with SDL
5. DBLG Announces Release 1.0 of the HITECH Act Survival Guide: an Open Source Law Initiative
6. Southwest Airlines Announces Recipients of its 2010 Medical Transportation Grant Program
7. Dr. David Williams Announces Launch of New Online Digestion Clinic
8. Code Hennessy & Simmons LLC Announces Sale of Suture Express, Inc.
9. Care Investment Trust Inc. Announces Stockholder Approval of Plan of Liquidation
10. PDL BioPharma Announces Two $0.50 Dividends in 2010
11. AMD Alliance International Announces $10,000 Video Contest
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/1/2014)... October 01, 2014 QueenBeeTickets.com is giving music ... the singer’s upcoming North American tour, which has him traveling ... come. , Click here to view the selection ... performer’s newest album, is due to come out on October ... shortly thereafter. Bob Seger concert tickets are available for shows ...
(Date:9/30/2014)... medical and nursing students in developing countries may have ... graduation, while less than one fifth of them intend ... most, according to a new study. , Health workforce ... outbreak of Ebola in western Africa. The disease initially ... world,s poorest countries (Guinea, Sierra Leone and Liberia), where ...
(Date:9/30/2014)... HealthDay Reporter TUESDAY, Sept. ... tend to put the brakes on motherhood. And for many ... permanent choice, new research suggests. Women in their early ... child during tough economic times. But, according to the new ... into their 40s and beyond. The findings suggest that ...
(Date:9/30/2014)... 2014 (HealthDay News) -- Sleep apnea is a potential health ... to a possible culprit behind the disorder: a "fat" tongue. ... deposits are increased in the tongue of obese patients with ... of the Sleep Center at the University of Pennsylvania Medical ... which will publish the findings Oct. 1. Sleep apnea ...
(Date:9/30/2014)... slow the spiraling costs of drugs paid for by ... no meaningful impact on cancer chemotherapy drug costs, say ... Clinical Oncology published online today. , "We looked ... lung cancers, and did not find a substantial change ... of the recent Medicare law in 2005," says the ...
Breaking Medicine News(10 mins):Health News:Bob Seger Presale Tickets: QueenBeeTickets.com Delights Fans with Discounted Tickets for All 20 Stops on Seger’s “Ride Out” Tour with The Silver Bullet Band 2Health News:Developing countries should enroll medical and nursing students from rural areas 2Health News:Developing countries should enroll medical and nursing students from rural areas 3Health News:Recessions May Thwart a Woman's Motherhood Plans Forever: Study 2Health News:Recessions May Thwart a Woman's Motherhood Plans Forever: Study 3Health News:Could a 'Fat Tongue' Be a Factor in Sleep Apnea? 2Health News:Landmark Medicare law had little impact on reducing chemotherapy cost 2
... Singh Saini might not enter the Guinness Book of World ... exam at the age// of 11 definitely makes her a ... of Dhanpat Singh Saini, a medical practitioner, passed her Class ... of Mangalam Vidhyapeeth School in the Basbadanpura area of this ...
... Commissioner of Prevention, Department of Health, Union government, held ... Thursday// to prepare for mass vaccination of children to ... is proposed from May 15 to May 30 and ... be covered during the drive. ,Biswal while ...
... the US National Cancer Institute in Bethesda, Maryland, and Jaakko ... that it is waste of time and money to search ... in the British Medical Journal. They say that there is ... lump of money is being invested. Researchers believe that if ...
... an ultra-modern medical college and hospital in his home district of ... Mata Janki Kunwar Hospital in Bettiah to a full-fledged medical college ... the development path. ,"I would love to help and ensure ... a visit here Friday. ,Jha's announcement has come at ...
... is awarded the Australian Mother of the Year. She is the ... philanthropist working for the welfare// of many who are in need. ... , This was in lieu of the Mother's Day celebration held ... has devoted 15 years of her entire life for serving disabled ...
... conducted in Madhya Pradesh has stated that more than 70 ... a part of curriculum in schools//. ,The Madhya Pradesh ... age group 10 to 19 years in 12 districts of ... education, saying the awareness would help them remain healthy and ...
Cached Medicine News:Health News:Jaipur Girl’s Rare Feat: The Youngest To Pass Class 12 At The Age Of 1 2Health News:The Department of Health Gears Up To The Arrival Of JE Vaccines 2Health News:Girls In MP Want Sex Education In Schools: Health Survey 2
(Date:9/30/2014)... , Sept. 30, 2014  Wrightington, Wigan ... Allscripts (NASDAQ: MDRX ) are delighted to ... as WWL,s new health information system. The system will ... completely transform the way WWL delivers healthcare in the ... a demonstrated record of on-time and on-budget system implementations ...
(Date:9/30/2014)... 30, 2014 This study provides an ... informatics solutions including nuclear imaging informatics, PET imaging ... study assesses the size of the market based ... and projects future growth based on the current ... taking place in the broader markets for imaging ...
(Date:9/30/2014)... , Sept. 30, 2014  Decision Resources Group ... in Brazil , Russia ... China (BRIC) will see robust expansion ... increasingly favored over surgical procedures. Although revenues will be ... reimbursement challenges, prolonged device approval times and demand for ...
Breaking Medicine Technology:Wrightington, Wigan and Leigh NHS Foundation Trust selects Allscripts Sunrise 2Wrightington, Wigan and Leigh NHS Foundation Trust selects Allscripts Sunrise 3Wrightington, Wigan and Leigh NHS Foundation Trust selects Allscripts Sunrise 4Analysis of the US Molecular Imaging Informatics Market 2Analysis of the US Molecular Imaging Informatics Market 3Brazilian, Russian, Indian and Chinese Markets for Peripheral Vascular Devices Will See Strong Expansion Through 2023 2Brazilian, Russian, Indian and Chinese Markets for Peripheral Vascular Devices Will See Strong Expansion Through 2023 3
... Feb. 23, 2011 Roche (SIX: RO, ROG; OTCQX: RHHBY) ... Department of Defense (DOD) to provide remote service and support ... the DOD,s secure B2B gateway. Roche is the first in-vitro ... for this remote access. The B2B gateway is ...
... Feb. 23, 2011 Xenogenics Corporation ("Xenogenics"), a majority ... MCET), is pleased to announce it has retained the ... of its capital formation strategy to help finance expanded ... In animal testing and initial human use, the ...
Cached Medicine Technology:Roche Teams with Womack Army Medical Center to Become First IVD Manufacturer approved for Remote Network Connectivity with DOD 2Xenogenics Corporation Retains the Emmes Group to Advise on Fund Raising Efforts 2Xenogenics Corporation Retains the Emmes Group to Advise on Fund Raising Efforts 3Xenogenics Corporation Retains the Emmes Group to Advise on Fund Raising Efforts 4
... MD Coder is simply more ... is a handheld solution for ... for both individual physicians and ... v6.0 now comes in three ...
The focus of HandEchart Professional is to offer a practical and basic electronic patient record keeping system that anyone can learn in minutes....
... 3000 is a computerized medical ... 3000 encompasses a wide array ... criteria sets and decision tree ... clinicians, medical educators, nurses and ...
... an advanced medical calculator and ... Dosing and Critical Care for ... logical complement to other PDA ... Daviss Drug Guide, PDR or ...
Medicine Products: