Navigation Links
FDA Advisory Committee Recommends Approval of KYNAPID(TM) for Acute Atrial Fibrillation
Date:12/11/2007

ith two late-stage clinical drug programs focused on atrial arrhythmia (intravenous and oral dosing), a Phase 1 program for GED-aPC, an engineered analog of recombinant human activated Protein C, and a pre-clinical program directed at improving cardiovascular function.

Vernakalant (iv) is the intravenous formulation of an investigational drug being evaluated for the acute conversion of atrial fibrillation. Positive top-line results from two pivotal Phase 3 trials for vernakalant (iv), called ACT 1 and ACT 3, were released in December 2004 and September 2005. Cardiome's co-development partner Astellas Pharma US, Inc. submitted a New Drug Application for vernakalant (iv) in December 2006. Positive top-line results from an additional Phase 3 study evaluating patients with post-operative atrial arrhythmia, called ACT 2, were released in June 2007. An open-label safety study evaluating recent-onset AF patients, called ACT 4, has completed.

Vernakalant (oral) is being investigated as a chronic-use oral drug for the maintenance of normal heart rhythm following termination of AF. Cardiome announced positive results from a Phase 2a pilot study for vernakalant (oral) in September 2006. A Phase 2b study for vernakalant (oral) is ongoing.

In April 2007 Cardiome acquired exclusive worldwide rights for GED-aPC for all indications. Cardiome intends to initially develop GED-aPC in cardiogenic shock, a life-threatening form of acute circulatory failure due to cardiac dysfunction, which is a leading cause of death for patients hospitalized following a heart attack.

Cardiome is traded on the Toronto Stock Exchange (COM) and the NASDAQ National Market (CRME).

About Astellas

Astellas Pharma US, Inc., located in Deerfield, Illinois, is a U.S. affiliate of Tokyo-based Astellas Pharma Inc. Astellas is a pharmaceutical company dedicated to improving the health of people around the world through the provision of innovative and reliable pharmaceutical
'/>"/>

SOURCE Cardiome Pharma Corp.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine news :

1. Genaera Announces Formation of Scientific Advisory Board for Obesity Drug Candidate Trodusquemine (MSI-1436)
2. China Holdings Appoints Ronald Shon Chairman of Advisory Board to Its Wholly-Owned Subsidiary China Power, Inc.
3. CryoCor Invited to Participate in FDA Advisory Panel Meeting on Atrial Fibrillation
4. Patient Safety Authority Board of Directors Names Infection Advisory Panel
5. Broker a Suite of Research & Advisory Services to Enhance Human Resources
6. Lynn Clark Callister, National Leader in Maternal-Child Health Nursing, Joins March of Dimes Advisory Council
7. MaxLife Fund Corp. appoints Daniel E. Kahan, to its Advisory Board
8. Delta Dental Plans Association Forms National Scientific Advisory Committee
9. Alter+Care Creates the Advisory Board
10. Patient Safety Authority Releases Advisory Focusing on Common Causes of Medication Errors
11. Susan G. Komen for the Cure Appoints Dr. Amelie G. Ramirez to Scientific Advisory Board
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/4/2015)... ... 2015 , ... According to an article published August 4th by ... data showing that it is safe for pregnant women to undergo local anesthesia needed ... local anesthesia with a group that hadn’t, researchers were able to determine that “local ...
(Date:9/4/2015)... ... September 04, 2015 , ... The Schmidt National Law Group filed an ... , Schmidt National Law Group, a leading firm in mass-tort litigation, has filed ... Corp., Bayer Essure, Inc., and other Bayer affiliates for injuries alleged to have been ...
(Date:9/4/2015)... Marietta, GA (PRWEB) , ... September 04, 2015 , ... ... team is in desperate need of new apparel. In an effort to assist the ... around Marietta, has launched a charity drive to raise funds for the new uniforms. ...
(Date:9/4/2015)... Valley Forge, PA (PRWEB) , ... September 04, 2015 , ... ... mold growth in and around the home is quite common. Mold can grow anywhere ... as areas around leaking pipes. Checking for excessive moisture and water in the home ...
(Date:9/4/2015)... , ... September 04, 2015 , ... Many consumers are looking for a quick and ... their solution. , The patent-pending K Med Cups provide a quick and simple way to ... relieve a cold, flu or cough. As a result, they enhance comfort and health. The ...
Breaking Medicine News(10 mins):Health News:Recent Study on Dental Care During Pregnancy Demonstrates How Preventative Dental Care Really is for Everyone, Says Medical Center Dental Care 2Health News:Schmidt National Law Group Files First Bayer Essure® Lawsuit in California 2Health News:The Jones Agency Serves Up a Charity Drive to Fund New Uniforms for the Sprayberry High School Girls Volleyball Team 2Health News:The Jones Agency Serves Up a Charity Drive to Fund New Uniforms for the Sprayberry High School Girls Volleyball Team 3Health News:September is Mold Awareness Month 2Health News:September is Mold Awareness Month 3Health News:September is Mold Awareness Month 4Health News:Redesigned Packaging for Powdered Medicinal Mix Invented by InventHelp® Client (CBA-2637) 2
... that head and neck cancer treatments fail is the tumor ... University of Michigan Comprehensive Cancer Center have found that a ... overcome that resistance. When researchers added a curcumin-based ... they were able to cut the dose of the chemotherapy ...
... A University of Missouri researcher has found that eating ... satiety and reduces hunger throughout the day. In addition, ... that eating a protein-rich breakfast reduces the brain signals ... knows that eating breakfast is important, but many people ...
... Barcelona researchers have discovered that Viagra drastically reduces multiple ... research, published in Acta Neuropathologica , demonstrates that ... animals after eight days of treatment. Researchers are confident ... patients given that the drug is well tolerated and ...
... The American Society of Clinical Oncology (ASCO) today ... more than 4,000 abstracts publicly posted online at www.asco.org ... additional 17 plenary, late-breaking and other major studies will ... Meeting. The meeting, which is expected ...
... , THURSDAY, May 19 (HealthDay News) -- Problem gambling ... especially online, of gambling opportunities, said experts who called ... the disorder. While most people gamble as an ... too seriously involved in terms of time invested and ...
... RECOMMENDS WAYS TO ENSURE ACCESS TO AFFORDABLE INSURANCE IS ... Combined Small Business and Individual Health Insurance Exchanges Could ... New York, NY, May 19, 2011Modifications to current policies ... provided under the Affordable Care Act remain stable even ...
Cached Medicine News:Health News:Curcumin compound improves effectiveness of head and neck cancer treatment, U-M study finds 2Health News:Eat a protein-rich breakfast to reduce food cravings, prevent overeating later, researcher finds 2Health News:Viagra could reduce multiple sclerosis symptoms 2Health News:ASCO releases studies from upcoming annual meeting 2Health News:ASCO releases studies from upcoming annual meeting 3Health News:Internet Is Playing a Part in Spread of Problem Gambling 2Health News:New report on health reform implementation: How to ensure access to coverage is maintained 2Health News:New report on health reform implementation: How to ensure access to coverage is maintained 3
(Date:9/4/2015)... 2015 Oramed Pharmaceuticals Inc. (NASDAQ: ... company focused on the development of oral drug delivery ... the upcoming Rodman & Renshaw 17 th Annual ... New York City .  Dr. ... corporate overview on September 9, 2015. ...
(Date:9/4/2015)... Sep. 04, 2015 ... the addition of the "Pharmacovigilance (London, UK ... offering. Understanding PhV today - the ... working in Drug safety. This course ... with pharmacovigilance. New entrants as well as experienced ...
(Date:9/4/2015)... Sep. 04, 2015 ... has announced the addition of the ... 2010-2019" report to their offering. ... containing repeating disaccharide units of Na-glucuronate-N-acetylglucosamine. As ... cartilage matrix, sodium hyaluronate can lubricate the ...
Breaking Medicine Technology:Oramed to Present at the Rodman & Renshaw Global Investment Conference 2Oramed to Present at the Rodman & Renshaw Global Investment Conference 3Pharmacovigilance Course: The Principles and Practice of Global PhV for those Working in Drug Safety (London, UK - December 7-9, 2015) 2Investigation Report on China's Sodium Hyaluronate Market 2015 2
... 1 October is American Pharmacists Month and ... provide outstanding care to their patients every day ... specialty pharmacies across the country. (Logo: ... Pharmacists Month is a time to recognize the ...
... national initiative, the Pediatric Trials Network (PTN), was created ... the National Institutes of Health (NIH).  The PTN will ... Shriver National Institute of Child Health and Human ... medical centers, including Children,s Mercy Hospitals and Clinics.   ...
Cached Medicine Technology:CVS Caremark Recognizes Its 26,000 Pharmacists During October's American Pharmacists Month 2New National Program to Study and Establish Pediatric Dosing 2New National Program to Study and Establish Pediatric Dosing 3
The Compass Commander series is engineered to provide the discriminating neurosurgeon with the same capabilities offered within the commander plus+, all in a smaller, lower-cost package....
Used for access and catheterization procedures. Double flexible tipped design permits alternative use of both ends of wire guide depending upon procedural needs. Supplied sterile in peel-open package...
Used for access and catheterization procedures. Double flexible tipped design permits alternative use of both ends of wire guide depending upon procedural needs. Supplied sterile in peel-open package...
... Coronary Stent System is Guidant's first in ... Cobalt chromium is stronger and more radiopaque ... stent can have similar strength and visibility ... struts that are only .0032" thick. Thinner ...
Medicine Products: