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FDA Advisory Committee Recommendation on SEROQUEL XR Supplemental New Drug Applications
Date:4/8/2009

ent.com/prnews?Page=Quote&Ticker=AZN'> AZN) is engaged in the research, development, manufacturing and marketing of meaningful prescription medicines and in the supply of healthcare services. AstraZeneca is one of the world's leading pharmaceutical companies with global healthcare sales of $ 31.6 billion and is a leader in gastrointestinal, cardiovascular, neuroscience, respiratory, oncology and infectious disease medicines. In the United States, AstraZeneca is a $13.5 billion dollar healthcare business. For more information about AstraZeneca in the US or our AZ&Me? Prescription Savings programs, please visit: www.astrazeneca-us.com.

The statements contain herein include forward-looking statements. Although we believe our expectations are based on reasonable assumptions, any forward-looking statements, by their very nature, involve risks and uncertainties and may be influenced by factors that could cause actual outcomes and results to be materially different from those predicted. The forward-looking statements reflect knowledge and information available at the date of the preparation of this press release and the Company undertakes no obligation to update these forward-looking statements. Important factors that could cause actual results to differ materially from those contained in forward-looking statements, certain of which are beyond our control, include, among other things, those risk factors identified in the Company's Annual Report/Form 20-F for 2007. Nothing contained herein should be construed as a profit forecast.

NOTES TO EDITORS:

    Questions to the Advisory Committee              Yes   No   Abstain
    1. Has SEROQUEL XR been shown to be effective
     as a treatment of:
    -- MDD as an adjunct therapy?                      9    1        0
    -- MDD as a monotherapy?                           8    1        1
    -
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SOURCE AstraZeneca
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