Navigation Links
FDA Advisers Back Anemia Drugs for Kidney Patients
Date:10/19/2010

ents.

"The label should be adjusted, but I just don't think we have enough information to recommend a fixed dose," Dr. Judith Hochman, head of cardiology at NYU School of Medicine, told the AP.

The study published last spring, a meta-analysis of 27 trials that included more than 10,000 people who were given the erythropoiesis-stimulating agents (ESAs), found that those who took the drugs to achieve the highest blood hemoglobin targets had a 51 percent increased risk for stroke and a 33 percent increased risk for thrombosis, or blockage of an artery. The study, by an international group of experts, was published online May 3 in Annals of Internal Medicine.

The increased risk for death (9 percent) and serious cardiovascular events such as heart attacks (15 percent) did not reach statistical significance, the analysis found.

The FDA has acted to control the use of ESAs in the past, and the agency has added a "black box" warning of dangers to the drugs' labeling.

Last spring's study added emphasis to such moves, Dr. Ajay K. Singh, an associate professor of medicine at Harvard Medical School and a nephrologist at Brigham and Women's Hospital in Boston, told HealthDay at the time.

"This meta-analysis shows increased risk with no benefit," Singh said. "The supposed benefit is that ESAs improve quality of life and make people feel better. This study suggests that these drugs, used at considerable cost, don't show any benefit in terms of those endpoints."

ESAs cost Medicare $2 billion a year, Singh said, making them the most expensive drugs in terms of cost that the government has paid for.

Yet ESAs do have a role in treating some people with chronic kidney disease, despite their dangers, Singh said.

New FDA rules, put into effect earlier this year, require that Amgen, the company that markets the drugs, disseminate a guide informing all patients of the drugs' risks and that doctors discuss those
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3 4

Related medicine news :

1. FDA Advisers Consider Approval of Genetically Modified Salmon
2. FDA Advisers Weigh Approval of Genetically Modified Salmon
3. FDA Advisers Divided on Whether to Ban Diet Drug Meridia
4. FDA Advisers Say Avastin Shouldnt Be Used for Breast Cancer
5. FDA to Broaden Disclosure on Advisers Conflicts of Interest
6. FDA Advisers Urge Stricter Regulation of Tanning Beds
7. Anemia Drugs Could Pose Threat to Some Kidney Patients
8. Stroke prevention study in children with sickle cell anemia, iron overload stopped early
9. OHSU joins forces with UO, Harvard to accelerate Fanconi anemia research
10. Anemia Drugs Hold Dangers for Kidney Patients
11. Anemia Harder to Treat in Black Children With Kidney Disease
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
FDA Advisers Back Anemia Drugs for Kidney Patients
(Date:8/1/2014)... Summer is here, and with it comes the ... and they can be a pain for dogs. Animal Emergency ... their customers get rid of ticks and prevent them completely. ... the summer, which is why they are so active during ... woodland areas and carry a number of diseases, including lyme ...
(Date:8/1/2014)... a cancer diagnosis may improve health outcomes for Asian-American ... a researcher at the University of Houston (UH). ... is the writing instruction. Otherwise, writing is just like ... can be therapeutic, but oftentimes we don,t get the ... said Qian Lu, assistant professor and director of the ...
(Date:8/1/2014)... Hawley, PA (PRWEB) August 01, 2014 Hot ... in the destination spa category of the World’s Best ... kicks off a month-long celebration of National Relaxation Day (technically ... together a series of MAJOR experts to help guests celebrate ... how important it is for health and wellness to carve ...
(Date:8/1/2014)... HealthDay Reporter FRIDAY, Aug. ... as a time-honored destination for a good cut and conversation. ... also be the spot to tackle an often overlooked health ... novel partnership, the U.S. Centers for Disease Control and Prevention, ... the help of barbershop staff to both discuss and diagnose ...
(Date:8/1/2014)... Abington, PA (PRWEB) August 01, 2014 ... beneficial than bottle-feeding. A recent study conducted ... may not lag too far behind in terms of ... simply want to know what’s best for their baby. ... , According to Dr. Steven Shapiro , chair ...
Breaking Medicine News(10 mins):Health News:Tis the Season for Tick Prevention 2Health News:Expressive writing may help breast cancer survivors 2Health News:Expressive writing may help breast cancer survivors 3Health News:The Lodge at Woodloch Kicks Off National Relaxation Day with a Month Long Celebration 2Health News:The Lodge at Woodloch Kicks Off National Relaxation Day with a Month Long Celebration 3Health News:The Lodge at Woodloch Kicks Off National Relaxation Day with a Month Long Celebration 4Health News:Barbershops Join Fight Against High Blood Pressure in Black Men 2Health News:Barbershops Join Fight Against High Blood Pressure in Black Men 3Health News:Despite Recent Study, Abington Health Expert Encourages Breastfeeding 2Health News:Despite Recent Study, Abington Health Expert Encourages Breastfeeding 3
... change your genes, say researchers after success in a ... McGill University in Montreal have found that nutrients // ... certain genes in rodents, reports science portal EurekAlert., ... a two-year-old study, which showed that the activity of ...
... for losing teeth as is generally known, but there ... said study author Dr. Khalaf F. Al-Shammari, of Kuwait ... educating the public about these factors that appear to ... increased attention to avoiding such factors.' Al-Shammari and colleagues ...
... first Phase III study involving the use of Actemra ... it is superior to conventional treatment modality that uses ... destruction. It has also been found to provide symptomatic ... arthritis is a debilitating autoimmune disease in which the ...
... Recent research conducted at the Ohio State University shows ... of cancer deaths involves the loss of an essential ... muscular // dystrophy. , ,The study findings, which ... Cell, show that muscle cells lose significant amounts of ...
... Thousands of patients in the United Kingdom may be at ... A poll ,conducted by a team of researchers randomly on ... of their // patients were overdosing on vitamins and remained ... , ,A large number of patients were ignorant about ...
... loss of virginity affects men and women across the spectrum is ... First Sexual Experiences. This is the first book of its kind ... the most important events in life. We all read and hear ... sex, but it doesn't tell us what losing their virginity means ...
Cached Medicine News:Health News:Food Habits Could Change Your Genes 2Health News:Novel Actemra monotherapy in treating patients with early aggressive rheumatoid arthritis 2Health News:Loss Of Dystrophin: Common Thread In Cancer And MS Muscle Wasting 2Health News:Vitamin Abuse Syndrome In the UK 2
(Date:8/1/2014)... Medical, Inc. (Nasdaq: NXTM ), a leading manufacturer ... Burbank , Chief Executive Officer, and Mathew Towse , ... Annual Canaccord Genuity Growth Conference being held at the InterContinental ... 13 th at 4:30 p.m. ET.  A webcast of ... About NxStage Medical NxStage Medical, ...
(Date:8/1/2014)... , Aug. 1, 2014  Neuland Laboratories Ltd., ... active pharmaceutical ingredients (APIs), complex intermediates and ... in 85 countries, today announced financial results for ... ended June 30, 2014. "Neuland,s results ... flow re-prioritization to accommodate certain customer needs, and ...
(Date:8/1/2014)... Aug. 1, 2014 Dyadic International, Inc. ("Dyadic") ... proprietary technologies are used to develop, manufacture and sell ... biopharmaceutical and industrial enzyme industries, announced today that it ... ended June 30, 2014 after market close on Thursday, ... that day at 5:00 p.m. Eastern Time to discuss ...
Breaking Medicine Technology:NxStage to Present at the 34th Annual Canaccord Genuity Growth Conference 2Neuland Labs Reports First Quarter Fiscal Year 2015 Financial Results 2Neuland Labs Reports First Quarter Fiscal Year 2015 Financial Results 3Dyadic International To Announce Second Quarter 2014 Financial Results And Host Conference Call On Thursday, August 14, 2014 2Dyadic International To Announce Second Quarter 2014 Financial Results And Host Conference Call On Thursday, August 14, 2014 3
... Second Generation Oxazolidinone Demonstrates Safety and Efficacy with Once-Daily, ... of Treatment , , SAN DIEGO, June ... its Phase 2 clinical trial evaluating the safety and ... the treatment of severe complicated skin and skin structure ...
... sets to be released-- , , PARIS, ... in patients with blepharospasm and cervical dystonia -- one placebo-controlled ... presented at the Movement Disorder Society (MDS) 13th annual International ... Pharmaceuticals, which plans to file a Biologic License Application (BLA) ...
Cached Medicine Technology:Trius Announces Positive Results From Phase 2 Clinical Trial of Torezolid in Patients With Complicated Skin and Skin Structure Infections 2Trius Announces Positive Results From Phase 2 Clinical Trial of Torezolid in Patients With Complicated Skin and Skin Structure Infections 3Trius Announces Positive Results From Phase 2 Clinical Trial of Torezolid in Patients With Complicated Skin and Skin Structure Infections 4Merz Pharmaceuticals Announces Results of Clinical Trials with NT-201(Botulinum neurotoxin type A free from complexing proteins) at Annual Movement Disorders Society Meeting 2Merz Pharmaceuticals Announces Results of Clinical Trials with NT-201(Botulinum neurotoxin type A free from complexing proteins) at Annual Movement Disorders Society Meeting 3Merz Pharmaceuticals Announces Results of Clinical Trials with NT-201(Botulinum neurotoxin type A free from complexing proteins) at Annual Movement Disorders Society Meeting 4
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: