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Eye Scan Could Help Track Progress of Multiple Sclerosis
Date:12/25/2012

MONDAY, Dec. 24 (HealthDay News) -- In-office eye scans that assess the thinning of the retina may also help doctors determine how fast multiple sclerosis (MS) is progressing in patients with the nervous system disease, a new study suggests.

The study included 164 MS patients who underwent eye scans every six months for an average of 21 months. The participants also had MRI brain scans at the start of the study and yearly.

Patients with MS relapses had 42 percent faster retinal thinning than those with no relapses, the study found. Patients with inflammatory lesions called gadolinium-enhancing lesions had 54 percent faster retinal thinning, and those with new T2 lesions had 36 percent faster thinning, compared to patients who did not have evidence of such lesions on their MRI brain scans, the investigators found.

In addition, patients whose disability levels worsened during the study period had 37 percent more retinal thinning than those who had no changes in their disability levels.

And compared with patients who had the disease for more than five years, those who had MS for less than five years had 43 percent faster retinal thinning, the study authors noted.

The findings suggest that retinal thinning may occur faster in patients with earlier and more active MS.

The new report appears in the Jan. 1 online edition of the journal Neurology. It updates earlier results from this study, published in the Archives of Neurology in October.

"As more therapies are developed to slow the progression of MS, testing retinal thinning in the eyes may be helpful in evaluating how effective those therapies are," study author Dr. Peter Calabresi, of the Johns Hopkins University School of Medicine, said in a journal news release.

Other experts not connected to the study agreed.

"This study reports an important link between the inflammatory and neurodegenerative aspects of MS that should l
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