Navigation Links
Eye Color May Help Predict Vitiligo Risk

TUESDAY, May 8 (HealthDay News) -- Eye color may help predict risk for vitiligo, an autoimmune disease in which the skin loses its pigment, a new study finds.

The study of nearly 3,000 non-Hispanic Americans of European descent found people with blue eyes are less likely to have vitiligo. Researchers also identified 13 new genes that may predispose people to the condition, which often results in uneven patches of white skin and hair.

About 27 percent of people with vitiligo had blue/gray eyes, compared with 52 percent of Americans of non-Hispanic European descent without the skin condition. Meanwhile, 43 percent of people with vitiligo had tan or brown eyes, compared with 27 percent Americans of non-Hispanic European descent. About 30 percent of the patients with vitiligo had green or hazel eyes.

Although the study focused on vitiligo, the researchers noted their findings could shed light on how eye color may help predict people's risk for melanoma. People with brown eyes are at lower risk of melanoma.

"Genetically, in some ways vitiligo and melanoma are polar opposites. Some of the same genetic variations that make one more likely to have vitiligo make one less likely to have melanoma, and vice versa," Dr. Richard Spritz, director of the Human Medical Genetics and Genomics Program at University of Colorado School of Medicine, said in a university news release. "Vitiligo is an autoimmune disease, in which a person's immune system attacks their normal pigment cells. We think that vitiligo represents overactivity of a normal process by which one's immune system searches out and destroys early cancerous melanoma cells."

Since people with vitiligo are at greater risk for other autoimmune diseases, such as thyroid disease and type 1 diabetes, the study's authors concluded their findings could help scientists learn more about the genetic basis for these diseases as well.

The study appeared online May 6 in Nature Genetics.

More information

The American Vitiligo Research Foundation provides more information on vitiligo and melanoma.

-- Mary Elizabeth Dallas

SOURCE: University of Colorado School of Medicine, news release, May 7, 2012

Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Eye color may indicate risk for serious skin conditions
2. Geisel researchers sift through junk to find colorectal cancer clues
3. Blacks and Hispanics at higher risk for precancerous colorectal polyps
4. Study says screening accounts for much of black/white disparity in colorectal cancer
5. Researchers uncover a viable way for colorectal cancer patients to overcome drug resistance
6. Study shows colorectal cancer screening rates high in patients with multiple health problems
7. American College of Physicians releases new colorectal cancer screening guidance statement
8. Legislation introduced to guarantee free colorectal cancer screening for all medicare beneficiaries
9. Obesity may modify the association between alcohol consumption and the risk of colorectal cancer
10. Inflammatory mediator promotes colorectal cancer by stifling protective genes
11. New test offers greater accuracy in early detection of colorectal cancer
Post Your Comments:
(Date:6/24/2016)... ... ... Marcy was in a crisis. Her son James, eight, was out of control. Prone to ... , “When something upset him, he couldn’t control his emotions,” remembers Marcy. “If there ... my other children and say he was going to kill them. If we were ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas ... , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct ...
(Date:6/24/2016)... ... 2016 , ... People across the U.S. are sharpening their pencils and honing ... contest in which patients and their families pay tribute to a genetic counselor by ... Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. , In ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... The Grove Investment Group (TGIG), has initiated cultivation and processing operations at its ... Vegas and Pahrump, Nevada. , Puradigm is the manufacturer of a complete system ...
(Date:6/24/2016)... ... June 24, 2016 , ... Venture Construction Group (VCG) ... held on June 20th at the Woodmont Country Club at 1201 Rockville Pike, ... organization dedicated to helping service members that have been wounded in battle and their ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... --  Pulmatrix, Inc ., (NASDAQ: PULM ), ... today that it was added to the Russell Microcap ... set of U.S. and global equity indexes on June ... for Pulmatrix," said Chief Executive Officer Robert Clarke ... in developing drugs for crucial unmet medical needs, and ...
(Date:6/23/2016)... Calif. , June 23, 2016 Any dentist ... many challenges of the current process. Many of them do ... of the technical difficulties and high laboratory costs involved. And ... to offer it at such a high cost that the ... it. Dr. Parsa Zadeh , founder of ...
(Date:6/23/2016)... June 23, 2016 Capricor ... ), a biotechnology company focused on the discovery, ... that patient enrollment in its ongoing randomized HOPE-Duchenne ... exceeded 50% of its 24-patient target. Capricor expects ... third quarter of 2016, and to report top ...
Breaking Medicine Technology: