Navigation Links
Eye Blinks May ID Fetal Alcohol Exposure

Study links a brain area to later learning deficits

MONDAY, Feb. 4 (HealthDay News) -- Eye blinking may help doctors identify children exposed to alcohol during pregnancy but who don't have the distinctive facial features usually associated with the exposure, a new study suggests.

"Eyeblink conditioning (EBC) is a Pavlovian paradigm that involves temporal pairing of a conditioned stimulus, such as a tone, with an unconditioned stimulus, such as an air puff," study first author Sandra W. Jacobson, a professor in the department of psychiatry and behavioral neurosciences at Wayne State University School of Medicine, said in a prepared statement.

"Animal studies have shown that binge consumption of alcohol during pregnancy impairs EBC. We wanted to see if we could use the EBC paradigm to identify underlying or subcortical deficits that are specifically affected by prenatal alcohol exposure in children," Jacobson said.

She and her colleagues administered EBC (which paired a tone with an air puff) to 98 South African 5-year-olds and found a link between EBC deficit and fetal alcohol exposure.

"Our results show that there was a dose-response relation between alcohol exposure and FASD [fetal alcohol spectrum disorder] diagnosis and that a fundamental element of learning is affected by prenatal alcohol exposure," Jacobson said. "We next need to extend the study of the EBC paradigm with fetal alcohol-exposed children to see how their exposure impacts on children at different ages."

The findings were published in the February issue of the journal Alcoholism: Clinical & Experimental Research.

"This study clearly links one brain area to the learning deficits experienced by FAS children, whether or not they have physical manifestations of the condition, and thus can provide a basis for the development of remediation programs," Lynn T. Singer, deputy provost and vice president for academic programs at Case Western Reserve University in Cleveland, said in a prepared statement.

"Second, since normal human infants reach functional capacity on the EBC response by five months of age, and since the EBC deficit appears to be so sensitive, infants at risk can be identified early in life, and intervention programs can begin when the plasticity of the brain is greatest and have the strongest effect," Singer said.

More information

The Nemours Foundation has more about fetal alcohol syndrome.

-- Robert Preidt

SOURCE: Alcoholism: Clinical & Experimental Research, news release, Feb. 3, 2008

Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Fetal surgeon shows for first time that laser procedure may treat vasa previa
2. Fetal Alcohol Exposure May Prime Offspring for Alcoholism
3. Procedure to detect fetal heart defects is first automated use of 3-D ultrasound
4. Fetal Exposure to Arsenic Affects Genes
5. Fetal Heart Rate Points to Later Child Development
6. Fetal heart rate yields clues to childrens later development
7. Fetal Surgery Saves Baby After Early Water Break
8. Fetal cell transplant could be a hidden link between childbirth and reduced risk of breast cancer
9. Residual fetal cells in women may provide protection against breast cancer
10. Mothers Blood Could Offer Insights Into Fetal Health
11. Parental Drinking Boosts Teen Alcohol Risks
Post Your Comments:
(Date:11/30/2015)... ... November 30, 2015 , ... Olympic Gold ... are collaborating with brands across various categories through traditional and social media marketing ... an elite group of Gold Medal Moms who can connect with today’s most ...
(Date:11/30/2015)... ... , ... The National Association of Professional Women (NAPW) honors ... Circle. She is recognized with this prestigious distinction for leadership in estate sales and ... than 850,000 members and over 200 operating Local Chapters. , “I’m pleased to welcome ...
(Date:11/30/2015)... ... November 30, 2015 , ... Being a caregiver for someone ... Maryland Health Care System, the Caregiver Support Program promotes the health and wellbeing ... job. Seventy-four percent report that their role as a caregiver has created marital ...
(Date:11/30/2015)... ... November 30, 2015 , ... According to research by the ... dental technicians to be certified or obtain continuing education. To increase awareness of ... Your Mouth?” campaign to inform dentists that the technicians they trust could lack ...
(Date:11/30/2015)... ... November 30, 2015 , ... The Museum ... summer, ushering in a new era of publicly accessible automated technology. Now, by ... continue to offer guests an up-close look at the shuttle at MOSI’s main ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... Express Scripts (NASDAQ: ESRX ) today announced it will ... access to a low-cost alternative to Daraprim (pyrimethamine) , ... recently priced out of reach for people with HIV, pregnant ... --> --> Imprimis is offering a compounded ... acid) for $1 per capsule for people whose pharmacy benefit is ...
(Date:11/30/2015)... SINGAPORE , Nov. 30, 2015  QT Vascular ... Vascular", and together with its subsidiaries, TriReme Medical LLC ... global company engaged in the design, assembly and distribution ... of vascular disease, is pleased to announce that a ... Court of Appeals for the Federal Circuit ("Federal ...
(Date:11/30/2015)... , Nov. 30, 2015   Royal ... announced the launch of Radiology Solutions, a fully ... Radiology Solutions comprises customized, data-driven practice management approaches ... to help radiology practices improve care delivery and ... 2015 Radiological Society of North America Annual Meeting ...
Breaking Medicine Technology: