Navigation Links
Eye Blinks May ID Fetal Alcohol Exposure
Date:2/4/2008

Study links a brain area to later learning deficits

MONDAY, Feb. 4 (HealthDay News) -- Eye blinking may help doctors identify children exposed to alcohol during pregnancy but who don't have the distinctive facial features usually associated with the exposure, a new study suggests.

"Eyeblink conditioning (EBC) is a Pavlovian paradigm that involves temporal pairing of a conditioned stimulus, such as a tone, with an unconditioned stimulus, such as an air puff," study first author Sandra W. Jacobson, a professor in the department of psychiatry and behavioral neurosciences at Wayne State University School of Medicine, said in a prepared statement.

"Animal studies have shown that binge consumption of alcohol during pregnancy impairs EBC. We wanted to see if we could use the EBC paradigm to identify underlying or subcortical deficits that are specifically affected by prenatal alcohol exposure in children," Jacobson said.

She and her colleagues administered EBC (which paired a tone with an air puff) to 98 South African 5-year-olds and found a link between EBC deficit and fetal alcohol exposure.

"Our results show that there was a dose-response relation between alcohol exposure and FASD [fetal alcohol spectrum disorder] diagnosis and that a fundamental element of learning is affected by prenatal alcohol exposure," Jacobson said. "We next need to extend the study of the EBC paradigm with fetal alcohol-exposed children to see how their exposure impacts on children at different ages."

The findings were published in the February issue of the journal Alcoholism: Clinical & Experimental Research.

"This study clearly links one brain area to the learning deficits experienced by FAS children, whether or not they have physical manifestations of the condition, and thus can provide a basis for the development of remediation programs," Lynn T. Singer, deputy provost and vice president for academic programs at Case Western Reserve University in Cleveland, said in a prepared statement.

"Second, since normal human infants reach functional capacity on the EBC response by five months of age, and since the EBC deficit appears to be so sensitive, infants at risk can be identified early in life, and intervention programs can begin when the plasticity of the brain is greatest and have the strongest effect," Singer said.

More information

The Nemours Foundation has more about fetal alcohol syndrome.



-- Robert Preidt



SOURCE: Alcoholism: Clinical & Experimental Research, news release, Feb. 3, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Fetal surgeon shows for first time that laser procedure may treat vasa previa
2. Fetal Alcohol Exposure May Prime Offspring for Alcoholism
3. Procedure to detect fetal heart defects is first automated use of 3-D ultrasound
4. Fetal Exposure to Arsenic Affects Genes
5. Fetal Heart Rate Points to Later Child Development
6. Fetal heart rate yields clues to childrens later development
7. Fetal Surgery Saves Baby After Early Water Break
8. Fetal cell transplant could be a hidden link between childbirth and reduced risk of breast cancer
9. Residual fetal cells in women may provide protection against breast cancer
10. Mothers Blood Could Offer Insights Into Fetal Health
11. Parental Drinking Boosts Teen Alcohol Risks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/8/2016)... ... December 08, 2016 , ... ... has been recognized for adherence to the highest standards of trauma, maternity, cancer ... announced the center's president and CEO, Dr. Daniel Messina. , Among the recognitions, ...
(Date:12/8/2016)... Ga (PRWEB) , ... December 08, 2016 , ... ... as soon after surgery as possible. With this in mind, SIGVARIS has created ... (DVT or blood clot) during bed rest and provide the benefits of graduated ...
(Date:12/8/2016)... ... December 08, 2016 , ... Dickinson Insurance and Financial Services, ... Little Rock, has initiated a charity drive to provide support and funding to ... Senior Hunger, Arkansas ranks first in senior hunger statewide, third in child hunger, ...
(Date:12/8/2016)... ... December 08, 2016 , ... Peter Zipp Insurance, an ... around the greater Phoenix metropolitan region, is announcing a charity event to provide ... the Homeless Youth Connection is to promote community awareness of the ongoing needs ...
(Date:12/8/2016)... ... December 08, 2016 , ... Coffey Agencies, a locally ... commercial clients in the northern Alabama and Georgia regions, is embarking on a ... Nobis Works has built a network of support and education facilities to develop ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... , Dec. 8, 2016  EIP Pharma, LLC ... obtained proof-of-mechanism for neflamapimod (previously code named VX-745), ... 2a clinical trials that demonstrated significant Alzheimer,s disease ... (12-week treatment) and Study 303 (6-week treatment) are ... in Alzheimer,s Disease (CTAD) scientific conference in ...
(Date:12/8/2016)... 2016 Dignitana, a world leader in medical ... Technology, creator of the award-winning, patented Boa® system, to ... the DigniCap® scalp cooling system. DigniCap® was cleared by ... and is the first medical scalp cooling device to ... system features a patented tight-fitting silicone cooling cap that ...
(Date:12/8/2016)... SAN DIEGO , Dec. 8, 2016 /PRNewswire/ ... dedicated to improving cancer patient care from diagnosis ... the company,s recently completed Phase 1b study in ... at the San Antonio Breast Cancer Symposium. ... Cancer Center at UC San Diego Health, delivered ...
Breaking Medicine Technology: