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Extracts of catfish caught in polluted waters cause breast cancer cells to multiply
Date:11/7/2007

onsive and estrogen non-responsive human breast cancer cells. They found that catfish extracts caused the estrogen-responsive breast cancer cells to multiply by binding to and activating estrogen receptors the proteins within cells that render the cells sensitive to estrogen but had no effect on the estrogen negative cell line. Extracts of fish caught in areas heavily polluted by industrial and municipal wastes resulted in the greatest amount of cell growth. This growth occurred regardless of the sex of the fish.

According to Dr. Volz, the next step in this research is to identify the specific estrogenic chemicals and their sources in the local water and fish. These findings have significant public health implications, since we drink water from the rivers where the fish were caught. Additionally, the consumption of river-caught fish, especially by semi-subsistence anglers, may increase their risks for endocrine-related health issues and developmental problems, said Dr. Volz.


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Contact: Clare Collins
CollCX@upmc.edu
412-647-3555
University of Pittsburgh Schools of the Health Sciences
Source:Eurekalert

Page: 1 2

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