Navigation Links
Extending treatment after liver transplant may benefit patients with hepatitis C recurrence
Date:10/31/2009

DETROIT Extending hepatitis C treatment for liver transplant patients beyond current practice results in high rates of clearance of the hepatitis C virus from the blood, as well as a low rate of relapse, according to a Henry Ford Hospital study.

"We found that patients who achieved a sustained virological response were more likely to have had extended treatment," says Kimberly Brown, M.D., Division head of Gastroenterology at Henry Ford Hospital and senior author of the study.

"In addition, prolonging treatment for 52 weeks after patients were virus negative, resulted in a relapse rate of only 8 percent." This is in contrast to typical relapse rates of 30-35 percent in non transplant patients treated with standard therapy.

Study results will be presented during an oral presentation Oct. 31 at the American Association for the Study of Liver Diseases' Annual Meeting in Boston.

The study looked at 241 consecutive liver transplant patients from 1999-2006. Patients were offered treatment if they tested positive hepatitis C, had recurrent hepatitis C with at least Stage I fibrosis on biopsy, and stable immunosuppression for a minimum of three months. Patients received either non-pegylated interferon tiw or pegylated interferon weekly in combination with ribavirin.

Of the study patients with hepatitis C, 66 were eligible for treatment, and 22 achieved sustained virological response. Only two patients (8 percent) relapsed.

After week 24 of treatment, 35 percent of patients who achieved a sustained virologic response became virus negative.

"These results call into question previous studies which suggested 'stop rules' at weeks 12 and 24 when there is no response to inferferon and ribravirin," says Dr. Brown. "Our results suggest that even if patients are positive at week 24, there is still a 35 percent chance that they can achieve sustained viral clearance. We think this may be beneficial to extend treatment beyond the standard 48 weeks total."

According to the U.S. Department of Health & Human Services, more than 16,000 liver transplants were performed last year and there are currently almost 18,000 Americans on the liver transplant list.


'/>"/>

Contact: Maria Seyrig
mseyrig1@hfhs.org
313-874-4039
Henry Ford Health System
Source:Eurekalert  

Related medicine news :

1. Study puts brakes on extending indications for cardiac resynchronization therapy
2. Haas TCM Acquires MC Technologies Extending Its Healthcare Environmental Information Management Systems and Chemical Management Services Offering
3. CDC Panel Urges Extending Flu Vaccine Coverage for Kids
4. The HealthCentral Network Acquires MedTrackAlert, Extending its Ability to Reach Highly Engaged Online Health Consumers
5. Fast Radios Introduces RoIP: Extending Two-Way Radio Range Thousands of Miles
6. Poll Shows Liberals Opposed to Extending Taxpayer Funded Healthcare to Illegal Immigrants
7. Sunrise Enters into 13th Amendment to Credit Agreement Extending Maturity Date to December 2, 2010
8. New treatment effective in counteracting cocaine-induced symptoms
9. New treatment boosts muscle function in myasthenia gravis
10. Broad-based group of physicians calls for improvement in stroke treatment
11. Cranberry Could Juice Up Ovarian Cancer Treatment
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Extending treatment after liver transplant may benefit patients with hepatitis C recurrence
(Date:6/28/2017)... (PRWEB) , ... June 28, 2017 , ... ... consulting firm servicing communities throughout the greater Cincinnati metropolitan area, is teaming up ... temporary lodgings for families with children receiving treatment in nearby hospitals. , Ronald ...
(Date:6/27/2017)... ... June 27, 2017 , ... DrugDev understands that for many ... trust the sponsor to pay them correctly and on time. As the search for ... strategies that encourage sites to work on their studies. , At a complimentary live ...
(Date:6/27/2017)... ... June 27, 2017 , ... The Congressional Budget Office (CBO) ... and replace the 2010 Patient Protection and Affordable Care Act (ACA), would result in ... be expected under current law. , More than 20 million Americans have gained health ...
(Date:6/27/2017)... (PRWEB) , ... June 27, 2017 , ... A January ... been projected to reach a staggering $6.81 billion by the year 2024 according to ... at a faster rate than those made from titanium. Los Angeles area clinic Beverly ...
(Date:6/27/2017)... , ... June 27, 2017 , ... ... to contribute to an upcoming case studies guidebook. This guidebook offers an excellent ... This book will include articles, case studies and how-to’s that fall into the ...
Breaking Medicine News(10 mins):
(Date:6/2/2017)... , June 2, 2017  NxStage Medical, Inc. (Nasdaq: ... care, today announced new findings demonstrating positive biochemical outcomes ... System One™. The data will be presented at ... Madrid, Spain . ... Improve Home Dialysis Network in Europe ...
(Date:5/30/2017)... 30, 2017 Hill-Rom Holdings, Inc. (NYSE: HRC), will ... Healthcare Conference on Tuesday, June 13, 2017, in ... Hill-Rom,s president and chief executive officer, is scheduled to present ... webcast can be accessed at http://ir.hill-rom.com/events.cfm . A recorded ... live event through September 13, 2017. ...
(Date:5/26/2017)... , May 26, 2017  Endo International plc (NASDAQ: ... , President and CEO, will represent the Company in a ... Healthcare Conference on Tuesday, June 13, 2017 at 10:40 a.m. ... at Terranea Resort in Rancho Palos Verdes, CA. ... for the event will be available on the Company,s website ...
Breaking Medicine Technology: