Navigation Links
Extended HPV Vaccine Schedule Seems Effective

TUESDAY, April 12 (HealthDay News) -- Giving doses of human papillomavirus (HPV) vaccine over a longer-than-normal period of time may prove an effective way to make the vaccine available to more females in poorer nations, a new study suggests.

HPV is a transmittable virus and the primary cause of cervical cancer, which kills about 275,000 women worldwide each year. About 88 percent of those deaths occur in developing nations, according to background information in the study.

"Combined with continued strengthening of simple evidence-based screening and treatment approaches, effective HPV vaccine programs could reduce cervical cancer rates in developing countries to the low levels currently observed in many developed countries," said Dr. Kathleen M. Neuzil, of PATH, a nonprofit organization located in Seattle whose stated mission is to improve global health, in a PATH news release. "One challenge to broadly implementing HPV vaccination programs in developing countries will be delivering the currently recommended three doses of vaccine to adolescents within six months (dosing schedules at 0, 2, and 6 months or at 0, 1, and 6 months)."

Even in countries where these dosing schedules are feasible, alternative dosing schedules may offer advantages such as lower cost (the vaccine could be given along with other health services) and increased coverage due to greater convenience for girls and their families or for vaccination teams, the study authors noted.

In this study, the researchers looked at four different dosing schedules used to give HPV vaccine to 903 adolescents girls at 21 schools in Vietnam. The doses were given according to a standard schedule of 0, 2 and 6 months or one of three alternative schedules (0, 3 and 9 months; 0, 6 and 12 months; or 0, 12 and 24 months).

The girls in the alternative dosing schedule groups developed antibody concentration levels similar to the girls in the standard dosing group, and no serious adverse events were reported.

The study findings are published in the April 13 issue of the Journal of the American Medical Association, a theme issue on infectious diseases and immunology.

"The similarity of the immunogenicity and reactogenicity profiles of the HPV vaccine reported from this predominantly ethnic minority population in a low-resource area of Vietnam and other populations throughout the world is reassuring and supports more widespread introduction of the vaccine. The World Health Organization acknowledges that programmatic constraints must be considered in the decision to commence national HPV immunization programs. The option of delivering HPV vaccine on flexible schedules will allow countries to minimize costs and maximize feasibility according to local vaccination practices," Neuzil's team concluded.

More information

The U.S. National Cancer Institute has more about HPV vaccination.

-- Robert Preidt

SOURCE: Journal of the American Medical Association, news release, April 12, 2011

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Lung cancer patients receiving palliative care had improved quality of life, extended survival
2. Extended use of anti-clotting drug helps some bedridden patients
3. Extended Sizes and Accessories for Medical Walking Boots are Now Available from Orthotics And Beyond
4. Vitamins for Life Inventory Extended to Wellness Products, Higher Nature Supplements
5. Treadmill Doctor 360 Degree Guarantee Extended Service Plans
6. BETE Fog Nozzle Announces HydroWhirl™ Orbitor – Clean-In-Place Rotating Tank Cleaning Machine with High Impact Cleaning for Extended Operating Life
7. Extended hepatitis C treatment after liver transplant may benefit patients
8. Alterian Announces Extended Partnership with youDb in Brazil
9. HITSP Contract With U.S. HHS Extended Through April 2010
10. Lengthening dosing schedule of HPV vaccine may provide effective option for expanding use of vaccine
11. Brain Tumor Vaccine Shows Promise in Early Trials
Post Your Comments:
Related Image:
Extended HPV Vaccine Schedule Seems Effective
(Date:11/28/2015)... ... November 28, 2015 , ... Trying to relax on a couch can actually ... conceived of this design due to personal experience with a bad back," he said. ... and convenience, as well as increases support. It also makes it easier to eat, ...
(Date:11/28/2015)... Viejo, CA (PRWEB) , ... November 28, 2015 , ... ... new fully customizable media panels to choose from, the possibilities are endless. Users have ... and more. With the ProPanel: Pulse masking effects, users are sure to get heads ...
(Date:11/27/2015)... CA (PRWEB) , ... November 27, 2015 , ... According ... at the recent 2015 American Dental Association meeting in Washington D.C. revolved around the ... protect a patient’s overall health. The talk stressed the link between periodontal disease (more ...
(Date:11/27/2015)... ... November 27, 2015 , ... According to an article published November ... they are handling security in light of the recent terrorist attacks in Paris, other ... to stop an attack from reaching U.S. soil. Especially around special events that may ...
(Date:11/27/2015)... ... November 27, 2015 , ... A team of Swiss doctors ... treat it. Surviving Mesothelioma has just posted the findings on the website. Click ... analyzed the cases of 136 mesothelioma patients who were treated with chemotherapy followed by ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... Research and Markets ( ) has announced ... Outlook to 2019 - Rise in Cardiac Disorders and Growing ... to their offering. Boston ... scientific and others. --> The market ... Boston scientific and others. ...
(Date:11/26/2015)... , November 26, 2015 ... the addition of the  "2016 Future ... Global Cell Surface Testing Market: Supplier ... to their offering.  --> ... of the  "2016 Future Horizons and ...
(Date:11/26/2015)... , November 26, 2015 ... the addition of the  "2016 Future ... European Therapeutic Drug Monitoring (TDM) Market: ... Intelligence, Emerging Opportunities"  report to their ... has announced the addition of the  ...
Breaking Medicine Technology: