otentially reduce the high risk of dangerous complications associated with diabetes such as life-threatening hypoglycemia, blindness, kidney failure, cardiac failure, and amputation. There are more than two million North Americans who have T1DM and more than twice as many with insulin dependent T2DM. In T2DM, insulin-secreting beta cell mass is already reduced by 50% at the time of diagnosis and continues to decline throughout the course of the disease. Patients with a significant loss of beta cell mass are totally dependent on injected insulin. Insulin therapy poses substantial challenges including danger of life threatening low blood sugar levels.
"We believe these trial results and further studies will confirm the potential for Exsulin as a breakthrough in diabetes treatment," said Lisa Jansa, founder and CEO, Exsulin Corporation. "Exsulin will soon begin new Phase II clinical trials at leading diabetes research centers."
About the Publication Authors
John Buse, MD, is past-president of American Diabetes Association (ADA) and is currently Professor of Medicine, Director, Diabetes Care Center and Chief, Division of Endocrinology and Executive Associate Dean for Clinical Research at the University of North Carolina School of Medicine, Chapel Hill, North Carolina. Robert Ratner, MD, is Associate Professor of Medicine, George Washington University School of Medicine, MedStar Research Institute. Kathleen Dungan, MD, is an endocrinologist, Division of Endocrinology, Diabetes, and Metabolism, The Ohio State University School of Medicine.
About Exsulin Corporation
Based in Minneapolis, Exsulin Corporation has global rights to a platform that enables research and development of islet cell regeneration approaches for reversing a fundamental cause of type 1 and type 2 diabetes. Exsulin aims to change the future of diabetes care and win significant cost savings for the healthcare s
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